{"aaData": [["1", "SMALL INTESTINE", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", ""], ["10", "STOMACH", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", ""], ["11", "COLON & RECTUM", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", ""], ["12", "ANAL CANAL", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", ""], ["13", "LIVER", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", "", ""], ["14", "GALLBLADDER", "", "", "", "", "", "", "", "", "", "", "", "
\nPrimary Tumor (T)\nT1b Melanoma < or = 1.0 mm in thickness and level IV or\n V or with ulceration\nT2 Melanoma 1.01 - 2 mm in thickness with or without ulceration\nT2a Melanoma 1.01 - 2 mm in thickness, no ulceration\nT2b Melanoma 1.01 - 2 mm in thickness, with ulceration\nT3 Melanoma 2.01 - 4 mm in thickness with or without ulceration\nT3a Melanoma 2.01 - 4 mm in thickness, no ulceration\nT3b Melanoma 2.01 - 4 mm in thickness, with ulceration\nT4 Melanoma greater than 4.0 mm in thickness with\n or without ulceration\n\nT4a Melanoma greater than 4.0 mm in thickness, no ulceration\nT4b Melanoma greater than 4.0 mm in thickness, with ulceration\nTX Primary tumor cannot be assessed (e.g. shave\n biopsy or regressed melanoma)\nT0 No evidence of primary tumor\nTis Melanoma 'in situ'\nT1 Melanoma < or = 1.0 mm in thickness with or without ulceration\nT1a Melanoma < or = 1.0 mm in thickness and level II or\n III, no ulceration\n\n
\nRegional Lymph Nodes (N)\nN2a Clinically occult (microscopic) metastasis\nN2b Clinically apparent (macroscopic) metastasis\nN2c Satellite or in-transit metastasis without nodal\n metastasis\nN3 Metastasis in four or more regional modes, or matted\n metastatic nodes, or in-transit metastasis or\n satellite(s) with metastasis in regional node(s)\n\nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Metastasis in one lymph node\nN1a Clinically occult (microscopic) metastasis\nN1b Clinically apparent (macroscopic) metastasis\nN2 Metastasis in 2 or 3 regional nodes or intralymphatic\n regional metastasis without nodal metastases\n\n
\nDistant Metastasis (M)\n metastasis at any site associated with an elevated\n serum lactic dehydrogenase (LDH) \n\nMX Distant metastasis cannot be assessed\nM0 No distant metastasis\nM1 Distant metastasis\nM1a Metastasis to skin, subcutaneous tissues\n or distant lymph nodes\nM1b Metastasis to lung\nM1c Metastasis to all other visceral sites or distant\n\n
\nPrimary Tumor (T)\n invades to papillary-reticular dermal interface (Clark's Level III)\nT3 Tumor more than 1.5 mm but not more than 4 mm in thickness and/or\n invades the reticular dermis (Clark's Level IV)\nT3a Tumor more than 1.5 mm but not more than 3 mm in thickness\nT3b Tumor more than 3 mm but not more than 4 mm in thickness\nT4 Tumor more than 4 mm in thickness and/or invades the subcutaneous tissue\n (Clark's Level V) and/or satellite(s) within 2 cm of the primary tumor\nT4a Tumor more than 4 mm in thickness and/or invades the subcutaneous tissue\nT4b Satellite(s) within 2 cm of the primary tumor\n\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nTis Melanoma 'in situ' (atypical melanocytic hyperplasia, severe melanocytic\n dysplasia), not an invasive malignant lesion (Clark's Level I)\nT1 Tumor 0.75 mm or less in thickness and invades the papillary dermis\n (Clark's Level II)\nT2 Tumor more than 0.75 mm but not more than 1.5 mm in thickness and/or\n\n
\nRegional Lymph Nodes (N)\nN2a Metastasis more than 3 cm in greatest dimension\n in any regional lymph node(s)\nN2b In-transit metastasis\nN2c Both (N2a and N2b)\n\nNote: In-transit metastasis involves skin or \nsubcutaneous tissue more than 2 cm from the\nprimary tumor but not beyond the regional lymph\nnodes.\n\nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Metastasis 3 cm or less in greastest dimension\n in any regional lymph node(s)\nN2 Metastasis more than 3 cm in greatest dimension\n in any regional lymph node(s) and/or in-transit\n metastasis\n\n
\nDistant Metastasis (M)\n\nMX Distant metastasis cannot be assessed\nM0 No distant metastasis\nM1 Distant metastasis\nM1a Metastasis in skin or subcutaneous\n tissue or lymph node(s) beyond the\n regional lymph nodes\nM1b Visceral metastasis\n\n
\nRegional Lymph Nodes (N) Pathologic\nN0(mol-) No regional lymph node metastasis histologically, negative\n molecular findings (RT-PCR)\nN0(mol+) No regional lymph node metastasis histologically, positive\n molecular findings (RT-PCR)\nN1 Metastasis in 1 to 3 axillary lymph nodes, and/or in internal\n mammary nodes with microscopic disease detected by sentinel\n lymph node dissection but not clinically apparent \nN1mi Micrometastasis (greater than 0.2 mm, none greater than 2.0 mm) \nN1a Metastasis in 1 to 3 axillary lymph nodes\nN1b Metastasis in internal mammary nodes with microscopic disease\n\n detected by sentinel lymph node dissection but not clinically\n apparent\nN1c Metastasis in 1 to 3 axillary lymph nodes and in internal mammary\n lymph nodes with microscopic disease detected by sentinel lymph\n node dissection but not clinically apparent\nN2 Metastasis in 4 to 9 axillary lymph nodes, or in clinically\n apparent internal mammary lymph nodes in the absence of axillary\n lymph node metastasis\nN2a Metastasis in 4 to 9 axillary lymph nodes (at least one tumor\n deposit greater than 2.0 mm)\nNX Regional lymph nodes cannot be assessed (eg, previously removed,\nN2b Metastasis in clinically apparent internal mammary lymph nodes in\n the absence of axillary lymph node metastasis\nN3 Metastasis in 10 or more axillary lymph nodes, or in infraclavicular\n lymph nodes, or in clinically apparent ipsilateral internal mammary\n lymph nodes in the presence of 1 or more positive axillary lymph\n nodes; or in more than 3 axillary lymph nodes with clinically\n negative microscopic metastasis in internal mammary lymph nodes; or\n in ipsilateral supraclavicular lymph nodes\nN3a Metastasis in 10 or more axillary lymph nodes (at least one tumor\n deposit greater than 2.0 mm), or metastasis to the infraclavicular\n or not removed for pathologic study)\n lymph nodes\nN3b Metastasis in clinically apparent ipsilateral internal mammary lymph\n nodes in the presence of 1 or more positive axillary lymph nodes;\n or in more than 3 axillary lymph nodes and in internal mammary\n lymph nodes with microscopic disease detected by sentiel lymph\n node dissection but not clinically apparent\nN3c Metastasis in ipsilateral supraclavicular lymph nodes\nN0 No regional lymph node metastasis histologically, no additional\n examination for isolated tumor cells (ITC)\nN0(i-) No regional lymph node metastasis histologically, negative IHC\nN0(i+) No regional lymph node metastasis histologically, positive IHC,\n no IHC cluster greater than 0.2 mm\n\n
\nRegional Lymph Nodes (N)\n and all less than 2 cm in greatest dimension\n N1bii Metastasis to 4 or more lymph nodes, any more than 0.2 cm\n and all less than 2 cm in greatest dimension\n N1biii Extension of tumor beyond the capsule of a lymph node\n metastasis less than 2 cm in greatest dimension\n N1biv Metastasis to a lymph node 2 cm or more in greatest dimension\nN2 Metastasis to ipsilateral axillary lymph nodes that are fixed to one\n another or to other structures\nN3 Metastasis to ipsilateral internal mammary lymph node(s)\n\nNX Regional lymph nodes cannot be assessed (e.g., previously\n removed, or not removed for pathologic study)\nN0 No regional lymph node metastasis\nN1 Metastasis to movable ipsilateral axillary lymph node(s)\n N1a Only micrometastasis (none larger than 0.2 cm)\n N1b Metastasis to lymph node(s), any larger than 0.2 cm\n N1bi Metastasis is 1 to 3 lymph nodes, any more than 0.2 cm\n\n
\nPrimary Tumor (T)\nT2b Tumor involves other pelvic tissues\nT3 Tumor infiltrates abdominal tissues\nT3a One site\nT3b More than one site\nT4 Tumor invades bladder or rectum\n \nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor limited to the uterus\nT1a Tumor 5 cm or less in greatest dimension\nT1b Tumor more than 5 cm\nT2 Tumor extends beyond the uterus, within the pelvis\nT2a Tumor involves adnexa\n\n
\nPrimary Tumor (T)\nT1c IC Tumor invades to more than one-half of the myometrium\nT2 II Tumor invades cervix but does not extend beyond uterus\nT2a IIA Endocervical glandular involvement only\nT2b IIB Cervical stromal invasion\nT3 III Local and/or regional spread as specified in T3a, b, and/or N1 and\n FIGO IIIA, B, and C below\nT3a IIIA Tumor involves serosa and/or adnexa (direct extension or meta-\n stasis) and/or cancer cells in ascites or peritoneal washings\nT3b IIIB Vaginal involvement (direct extension or metastasis)\nT4 IVA Tumor invades bladder mucosa and/or bowel mucosa\n\nTNM FIGO\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nTis Carcinoma 'in situ'\nT1 I Tumor confined to corpus uteri\nT1a IA Tumor limited to endometrium\nT1b IB Tumor invades up to or less than one-half of the myometrium\n\n
\nRegional Lymph Nodes (N)\n\nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Regional lymph node metastasis\n\n
\nDistant Metastasis (M)\n\nMX......Distant metastasis cannot be assessed\nM0......No distant metastasis\nM1......Distant metastasis\n\n
\nPrimary Tumor, Pathologic (T)\nT3 Extraprostatic extension\nT3a Extraprostatic extension or microscopic\n invasion of bladder neck\nT3b Seminal vesicle extension\nT4 Invasion of rectum, levator muscles, and/or\n pelvic wall\n \nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT2 Organ confined\nT2a Unilateral, one-half of one side or less\nT2b Unilateral, involving more than one-half of\n side but not both sides\nT2c Bilateral disease\n\n
\nRegional Lymph Nodes, Pathologic (N)\n\nNX Regional nodes not sampled \nN0 No positive regional nodes \nN1 Metastases in regional node(s) \n\n
\nDistant Metastasis (M)\n\nMX Distant metastasis cannot be assessed\n (not evaluated by any modality)\nM0 No distant metastasis\nM1 Distant metastasis\nM1a Non-regional lymph node(s)\nM1b Bone(s)\nM1c Other site(s) with or without bone disease\n\n
\nPrimary Tumor, Pathologic (T)\nT4 Invasion of bladder, rectum\n\nNote: There is no pathologic T1 classification.\n\nTX Primary tumor cannot be assessed\nT2 Organ confined\nT2a Unilateral\nT2b Bilateral\nT3 Extraprostatic extension\nT3a Extraprostatic extension\nT3b Seminal vesicle extension\n\n
\nRegional Lymph Nodes, Pathologic (N)\n\nNX Regional nodes cannot be not assessed \nN0 No regional lymph node metastasis \nN1 Metastases in regional lymph node or nodes \n\n
\nDistant Metastasis (M)\n\nMX Distant metastasis cannot be assessed\nM0 No distant metastasis\nM1 Distant metastasis\nM1a Nonregional lymph node(s)\nM1b Bone(s)\nM1c Other site(s)\n\n
\nRegional Lymph Nodes (N)\n cm but not more than 5 cm in greatest dimension;\n or more than 5 nodes positive, none more than 5 cm;\n or evidence of extranodal extension of tumor\nN3 Metastasis with a lymph node mass more than 5\n cm in greatest dimension\n\nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Metastasis with a lymph node mass, 2 cm or less\n in greatest dimension and less than or equal\n to 5 nodes positive, none more than 2 cm in\n greatest dimension\nN2 Metastasis with a lymph node mass, more than 2\n\n
\nRegional Lymph Nodes\n \nNX Regional lymph nodes cannot be assessed\nN0 No palpable or visibly enlarged inguinal lymph nodes\nN1 Palpable mobile unilateral inguinal lymph node\nN2 Palpable mobile multiple or bilateral inguinal lymph nodes\nN3 Palpable fixed inguinal nodal mass or pelvic lymphadenopathy\n unilateral or bilateral\n\n
\nUrothelial (Transitional Cell) Carcinoma of the Prostate\n prostatic stroma, corpus spongiosum,\n periurethral muscle\nT3 Tumor invades any of the following:\n corpus cavernosum, beyond prostatic capsule, \n bladder neck (extraprostatic extension)\nT4 Tumor invades other adjacent organs\n (invasion of the bladder)\n \nTis pu Carcinoma 'in situ', involvement of\n the prostatic urethra\nTis pd Carcinoma 'in situ', involvement of\n the prostatic ducts\nT1 Tumor invades subepithelial connective\n tissue\nT2 Tumor invades any of the following:\n\n
\nPrimary Tumor (T)\nT4 Tumor invades the eyelid, globe, orbit, sinuses,\n or central nervous system\n\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor of the bulbar conjunctiva\nT2 Tumor of bulbar conjunctiva with corneal\n extension\nT3 Tumor extending into the conjunctival fornix,\n palpebral conjuntiva, or caruncle\n\n
\nPrimary Tumor (T)\nT1c More than 2 but less than or equal to 3 quadrants\nT1d Greater than 3 quadrants\n \nMalignant conjunctival melanoma of the non-bulbar (palpebral, forniceal\ncaruncular)\nT2a Non-caruncular, less than or equal to 1 quadrant\nT2b Non-caruncular, greater than 1 quadrant\nT2c Any caruncular, less than or equal to 1 quadrant\nT2d Any caruncular, greater than 1 quadrant\n \n \nAny malignant conjunctival melanoma with local invasion\nT3a Globe\nT3b Eyelid\nT3c Orbit\nT3d Sinus\nT4 Tumor invades the central nervous system\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nTis Melanoma confined to the conjunctival epithelium\n \nMalignant conjunctival melanoma of the bulbar conjunctiva\nT1a Less than or equal to 1 quadrant\nT1b More than 1 but less than or equal to 2 quadrants\n\n
\nRegional Lymph Nodes (N)\n \nNX Regional lymph nodes cannot be assessed\nN0a No regional lymph node metastasis, biopsy performed\nN0B No regional lymph node metastasis, biopsy not performed\nN1 Regional lymph node metastasis\n\n
\nPrimary Tumor (T)\n palpebral conjuntiva and/or caruncle\nT4 Tumor invades eyelid, cornea, and/or\n orbit\n\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor(s) of bulbar conjunctiva occupying\n one quadrant or less\nT2 Tumor(s) of bulbar conjunctiva occupying\n more than one quadrant\nT3 Tumor(s) of conjunctival fornix and/or\n\n
\nRegional Lymph Nodes (N)\n\nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Regional lymph node metastasis\n\n
\nPrimary Tumor Pathologic (T)\nT2b Tumor invades choroid focally\nT2c Tumor invades optic nerve up to, but not through,\n the level of the lamina cribrosa and invades the choroid focally\nT3 Significant invasion of the optic nerve and/or optic coats\nT3a Tumor invades optic nerve through the level of the lamina cribrosa\n but not to the line of resection\nT3b Tumor massively invades the choroid\nT3c Tumor invades the optic nerve through the level of the lamina cribrosa\n but not to the line of resection and massively invades the choroid\nT4 Extraocular tumor extension\n\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor confined to the retina,vitreous, or subretinal space.\n No optic nerve or choroidal invasion.\nT2 Minimal invasion of the optic nerve and/or optic coats\nT2a Tumor invades optic nerve up to, but not through, the level\n of the lamina cribrosa\n\n
\nDistant Metastasis Pathologic (M)\n\nMX Distant metastasis cannot be assessed \nM0 No distant metastasis \nM1 Distant metastasis \nM1a Bone marrow \nM1b Other sites \n\n
\nPrimary Tumor (T)\n lamina cribrosa and exhibits focal choroidal invasion\nT3 Tumor with significant optic nerve and/or choroidal invasion\nT3a Tumor invades optic nerve past lamina cribrosa but not to surgical \n resection line or tumor exhibits massive choroidal invasion\nT3b Tumor invades optic nerve past lamina cribrosa but not to surgical \n resection line and exhibits massive choroidal invasion\nT4 Tumor invades optic nerve to resection line or exhibits extraocular \n extension elsewhere\nT4a Tumor invades optic nerve to resection line but no extraocular\n extension identified\n \nT4b Tumor invades optic nerve to resection line and extraocular extension\n identified\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor confined to eye with no optic nerve or choroidal invasion\nT2 Tumor with minimal optic nerve and/or choroidal invasion\nT2a Tumor superficially invades optic nerve head but does not extend past\n lamina cribrosa or tumor exhibits focal choroidal invasion\nT2b Tumor superficially invades optic nerve head but does not extend past\n\n
\nRegional Lymph Nodes (N)\n \nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node involvement\nN1 Regional lymph node involvement (preauricular, cervical)\nN2 Distant lymph node involvement\n\n
\nDistant Metastasis (M)\n \nM1 Metastasis to sites other than CNS\nM1a Single lesion\nM1b Multiple lesions\nM1c CNS metastasis\nM1d Discrete mass(es) without leptomeningeal and/or CSF involvement\nM1e Leptomeningeal and/or CSF involvement\n\n
\nPrimary Tumor Pathologic (T)\nT3a Tumor(s) involve(s) more than 50% of the retina\n and/or tumor cells in the vitreous\nT3b Tumor(s) involve(s) optic nerve\n as far as the lamina cribosa\nT3c Tumor(s) in anterior chamber and/or invasion with\n thickening of the uvea and/or intrascleral invasion\nT4 Tumor with extra-ocular invasion\nT4a Intraneural tumor beyond the lamina cribosa\n but not at the line of resection\nT4b Tumor at the line of resection or\n\n other extra-ocular extension\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor(s) limited to 25% or less of the retina\nT2 Tumor(s) involve(s) more than 25% but not more\n than 50% of the retina\nT3 Tumor(s) involve(s) more than 50% of the retina and/or\n invade(s) beyond the retina but remain(s) intra-ocular\n\n
\nRegional Lymph Nodes Pathologic (N)\n\nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Regional lymph node metastasis\n\n
\nPrimary Tumor, Pathologic (T)\nT3 Tumor of the bulbar conjunctiva more than 0.8 mm\n in thickness with invasion of the substantia\n propria or tumors involving the palpebral or\n caruncular conjunctiva\nT4 Tumor invades the eyelid, globe, orbit, sinuses,\n or central nervous system\n\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor of the bulbar conjunctiva confined to the\n epethelium\nT2 Tumor of the bulbar conjunctiva not more than\n 0.8 mm in thickness with invasion of the substantia\n propria\n\n
\nRegional Lymph Nodes (N)\n\nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Regional lymph node metastasis\n\n
\nPrimary Tumor (T)\nT1c Melanoma of the bulbar conjunctiva greater than 1.5 mm in thickness\n with invasion of the substantia propria\nT2a Melanoma of the palpebral, forniceal or caruncular conjunctiva not\n more than 0.5 mm in thickness with invasion of the substantia\n propria\nT2b Melanoma more than 0.5 but not greater than 1.5 mm in thickness with \n invasion of the substantia propria\nT2c Melanoma of the palpebral, forniceal or caruncular conjunctiva\n greater than 1.5 mm in thickness with invasion of the substantia\n propria\n \nT3 Melanoma invades the eye, eyelid, nasolacrimal system, sinuses or\n orbit\nT4 Melanoma invades the central nervous system\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nTis Melanoma confined to the conjunctival epithelium\nT1a Melanoma of the bulbar conjunctiva not more than 0.5 mm in thickness\n with invasion of the substantia propria\nT1b Melanoma of the bulbar conjunctiva more than 0.5 mm but not more than\n 1.5 mm in thickness with invasion of the substantia propria\n\n
\nPrimary Tumor, Pathologic (T)\n palpebral conjunctiva and/or caruncle or tumor(s)\n of the bulbar conjucntiva, more than 2 mm in thickness\nT4 Tumor invades eyelid, cornea, and/or orbit\n\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor(s) of the bulbar conjunctiva occupying\n one quadrant or less and 2 mm or less in thickness\nT2 Tumor(s) of the bulbar conjunctiva occupying\n more than one quadrant and 2 mm or less in thickness\nT3 Tumor(s) of the conjunctival fornix and/or\n\n
\nPrimary Tumor (T)\nT1b Tumor 10 mm or less in greatest diameter and 2.5 mm or less in greatest\n height (thickness) with microscopic extraocular extension\nT1c Tumor 10 mm or less in greatest diameter and 2.5 mm or less in greatest\n height (thickness) with macroscopic extraocular extension\nT2 Tumor greater than 10 mm but not more than 16 mm in greatest basal\n diameter and between 2.5 and 10 mm in maximum height (thickness)\nT2a Tumor 10 mm to 16 mm in greatest basal diameter and between 2.5 and 10 mm\n in maximum height (thickness) without microscopic extraocular extension\nT2b Tumor 10 mm to 16 mm in greatest basal diameter and between 2.5 and 10 mm\n in maximum height (thickness) with microscopic extraocular extension\nCiliary Body\nT2c Tumor 10 mm to 16 mm in greatest basal diameter and between 2.5 and 10 mm\n in maximum height (thickness) with macroscopic extraocular extension\nT3 Tumor more than 16 mm in greatest diameter and/or greater than 10 mm in\n maximum height (thickness) without extraocular extension\nT4 Tumor more than 16 mm in greatest diameter and/or greater than 10 mm in\n maximum height (thickness) with extraocular extension\n\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor 10 mm or less in greatest diameter and 2.5 mm or less in greatest\n height (thickness)\nT1a Tumor 10 mm or less in greatest diameter and 2.5 mm or less in greatest\n height (thickness) without microscopic extraocular extension\n\n
\nRegional Lymph Nodes (N)\n\nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Regional Lymph node metastasis\n\n
\nPrimary Tumor (T)\n extraocular extension less than or equal to 5 mm in diameter\nT1d Tumor size category 1 with ciliary body involvement and extraocular\n extension less than or equal to 5 mm in diameter\nT2 Tumor size category 2\nT2a Tumor size category 2 without ciliary body involvement and\n extraocular extension\nT2b Tumor size category 2 with ciliary body involvement\nT2c Tumor size category 2 without ciliary body involvement but with \n extraocular extension less than or equal to 5 mm in diameter\nT2d Tumor size category 2 with ciliary body involvement and extraocular\n \n extension less than or equal to 5 mm in diameter\nT3 Tumor size category 3\nT3a Tumor size category 3 without ciliary body involvement and\n extraocular extension\nT3b Tumor size category 3 with ciliary body involvement\nT3c Tumor size category 3 without ciliary body involvement but with \n extraocular extension less than or equal to 5 mm in diameter\nT3d Tumor size category 3 with ciliary body involvement and extraocular\n extension less than or equal to 5 mm in diameter\nT4 Tumor size category 4\nTX Primary tumor cannot be assessed\nT4a Tumor size category 4 without ciliary body involvement and\n extraocular extension\nT4b Tumor size category 4 with ciliary body involvement\nT4c Tumor size category 4 without ciliary body involvement but with \n extraocular extension less than or equal to 5 mm in diameter\nT4d Tumor size category 4 with ciliary body involvement and extraocular\n extension less than or equal to 5 mm in diameter\nT4e Any tumor size category with extraocular extension more than 5 mm in\n diameter\nT0 No evidence of primary tumor\nT1 Tumor size category 1\nT1a Tumor size category 1 without ciliary body involvement and\n extraocular extension\nT1b Tumor size category 1 with ciliary body involvement\nT1c Tumor size category 1 without ciliary body involvement but with \n\n
\nDistant Metastasis (M)\n \nM0 No distant metastasis\nM1 Distant metastasis\nM1a Largest diameter of the largest metastasis <=3 cm\nM1b Largest diameter of the largest metastasis 3.1-8.0 cm\nM1c Largest diameter of the largest metastasis 8.1 cm or more\n\n
\nPrimary Tumor (T)\n\nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor limited to ciliary body\nT2 Tumor invades into anterior chamber and/or iris\nT3 Tumor invades choroid\nT4 Tumor extraocular extension\n\n
\nPrimary Tumor (T)\n\nTX Primary tumor cannot be assessed\nT1 Limited patch/plaque \nT2 Generalized patch/plaque \nT3 Cutaneous tumors \nT4 Generalized erythroderma \n\n
\nRegional Lymph Nodes (N)\n\nNX Regional lymph nodes cannot be assessed\nN0 Lymph nodes clinically uninvolved \nN1 Lymph nodes clinically enlarged, histologically uninvolved \nN2 Lymph nodes clinically unenlarged, histologically involved \nN3 Lymph nodes enlarged and histologically involved \n\n
\nDistant Metastasis (M)\n\nMX Distant metastasis cannot be assessed\nM0 No visceral disease \nM1 Visceral disease present \n\n
\nPrimary Tumor (T) Skin\nT4 Confluence of erythema covering 80% body surface area\n \nT1 Limited patches, papules, and/or plaques covering <10% of the skin surface\n **per ISCL/EORTC: 'May further stratify into T1a (patch only) vs T1b\n (plaque +/- patch)'. The T1a & T1b values are not part of the AJCC algorithm.\nT2 Patches, papules or plaques covering 10% of the skin surface.\n **per ISCL/EORTC: 'May further stratify into T1a (patch only) vs T1b\n (plaque +/- patch)'. The T2a & T2b values are not part of the AJCC algorithm.\nT3 One or more tumors (1-cm diameter)\n\n
\nRegional Lymph Nodes (N)\nN2 Clinically abnormal peripheral lymph nodes; histopathology Dutch\n grade 2 or NCI LN3\nN2a Clone negative\nN2b Clone positive\nN3 Clinically abnormal peripheral lymph nodes; histopathology Dutch\n grades 3-4 or NCI LN4; clone positive or negative\n \nNX Clinically abnormal peripheral lymph nodes; no histologic\n confirmation\nN0 No clinically abnormal peripheral lymph nodes; biopsy not required\nN1 Clinically abnormal peripheral lymph nodes; histopathology Dutch\n grade 1 or NCI LN0-2\nN1a Clone negative\nN1b Clone positive\n\n
\nDistant Metastasis (M) Visceral\n \nM0 No visceral organ involvement\nM1 Visceral involvement (must have pathology confirmation and organ \n involved should be specified)\n\n
\nPrimary Tumor (T)\n \nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor 2 cm or less\nT2 Tumor more than 2 cm but not more than 5 cm\nT3 Tumor more than 5 cm but not more than 10 cm\nT4 Tumor more than 10 cm in greatest dimension\n\n
\nRegional Lymph Nodes (N)\n \nN0 No regional lymph node metastasis\nN1 Regional lymph node metastasis\n \nIf regional node status is unknown, use N0, not NX.\n\n
\nDistant Metastasis (M)\n \nM0 No distant metastasis\nM1 Distant metastasis\n\n
\nPrimary Tumor (T)\n adjacent structures\n \nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nTis Carcinoma in situ/dysplasia (tumor size <0.5mm), confined to mucosa\nT1 Tumor invades lamina propria or submucosa and 1cm in size\nT2 Tumor invades muscularis propria or >1cm in size\nT3 Tumor penetrates subserosa\nT4 Tumor invades visceral peritoneum (serosa) or other organs or\n\n
\nRegional Lymph Nodes (N)\n \nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Regional lymph node metastasis\n\n
\nDistant Metastasis (M)\n \nM0 No distant metastasis\nM1 Distant metastasis\n\n
\nPrimary Tumor (T)\n without penetration of overlying serosa (jejunal or ileal tumors) or\n invades pancreas or retroperitoneum (ampullary or duodenal tumors )\n or into nonperitonealized tissues.\nT4 Tumor invades visceral peritoneum (serosa) or invades other organs\n \nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor invades lamina propria or submucosa and size < or = 1 cm (small\n intestinal tumors); tumor < or = 1 cm (ampullary tumors)\nT2 Tumor invades muscularis propria or size >1 cm (small intestinal\n tumors); tumor >1 cm (ampullary tumors)\nT3 Tumor invades through the muscularis propria into subserosal tissue \n\n
\nRegional Lymph Nodes (N)\n \nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Regional lymph node metastasis\n\n
\nDistant Metastasis (M)\n \nM0 No distant metastasis\nM1 Distant metastasis\n\n
\nPrimary Tumor (T)\nT3 Tumor invades through the muscularis propria into the subserosa, or\n into non-peritonealized pericolic or perirectal tissues\nT4 Tumor invades peritoneum or other organs\n \nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor invades lamina propria or submucosa and size < or = 2 cm\nT1a Tumor size <1 cm in greatest dimension\nT1b Tumor size 1 to 2 cm in greatest dimension\nT2 Tumor invades muscularis propria or size >2 cm with invasion of\n lamina propria or submucosa\n\n
\nRegional Lymph Nodes (N)\n \nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Regional lymph node metastasis\n\n
\nDistant Metastasis (M)\n \nM0 No distant metastasis\nM1 Distant metastasis\n\n
\nPrimary Tumor (T)\n \nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nTis In situ primary tumor\nT1 Less than or equal to 2 cm maximum tumor dimension\nT2 Greater than 2 cm but not more than 5 cm maximum tumor dimension\nT3 Over 5 cm maximum tumor dimension\nT4 Primary tumor invades bone, muscle, fascia, or cartilage\n\n
\nRegional Lymph Nodes (N)\n \nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Metastasis in regional lymph node(s)\nN1a Micrometastasis\nN1b Macrometastasis\nN2 In transit metastasis\n\n
\nDistant Metastasis (M)\n \nM0 No distant metastasis\nM1 Metastasis beyond regional lymph nodes\nM1a Metastasis to skin, subcutaneous tissues or distant lymph nodes\nM1b Metastasis to lung\nM1c Metastasis to all other visceral sites\n\n
\nPrimary Tumor (T)\n \nT3 Mucosal disease\nT4a Moderately advanced disease\n Tumor involving deep soft tissue, cartilage, bone, or overlying skin.\nT4b Very advanced disease\n Tumor involving brain, dura, skull base, lower cranial nerves (IX, X,\n XI, XII), masticator space, carotid artery, prevertebral space, or\n mediastinal structures\n\n
\nRegional Lymph Nodes (N)\n \nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Regional lymph node metastasis present\n\n
\nDistant Metastasis\n \nM0 No distant metastasis\nM1 Distant metastasis\n\n
\nPrimary Tumor (T)\nT2 Tumor more than 2 cm but not more than 4 cm or with extension to the\n cecum\nT3 Tumor more than 4 cm or with extension to the ileum\nT4 Tumor directly invades other adjacent organs or structures, e.g., \n abdominal wall and skeletal muscle\n \nCarcinoid\n \nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor 2 cm or less in greatest dimension\nT1a Tumor 1 cm or less in greatest dimension\nT1b Tumor more than 1 cm but not more than 2 cm\n\n
\nRegional Lymph Nodes (N)\n \nCarcinoid\n \nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Regional lymph node metastasis\n\n
\nDistant Metastasis (M)\n \nCarcinoid\n \nM0 No distant metastasis\nM1 Distant metastasis\n\n
\nPrimary Tumor (T)\n mesenteric artery\nT4 Tumor involves the celiac axis, or the superior mesenteric artery\n \nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nTis Carcinoma in situ\nT1 Tumor confined to the bile duct histologically\nT2 Tumor invades beyond the wall of the bile duct\nT3 Tumor invades the gallbladder, pancreas, duodenum or other adjacent\n organs without involvement of the celiac axis, or the superior\n\n
\nRegional Lymph Nodes (N)\n \nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Regional lymph node metastasis\n\n
\nDistant Metastasis (M)\n \nM0 No distant metastasis\nM1 Distant metastasis\n\n
\nPrimary Tumor (T)\nT2a Tumor involves adnexa\nT2b Tumor involves other pelvic tissues\nT3 Tumor involves abdominal tissues\nT3a One site\nT3b More than one site\nT4 Tumor invades bladder or rectum\n \nTX Primary tumor cannot be assessed\nT0 No evidence of primary tumor\nT1 Tumor limited to the uterus\nT1a Tumor limited to the endometrium/endocervix\nT1b Tumor invades to less than half of the myometrium\nT1c Tumor invades more than half of the myometrium\nT2 Tumor extends beyond the uterus, within the pelvis\n\n
\nRegional Lymph Nodes (N)\n \nNX Regional lymph nodes cannot be assessed\nN0 No regional lymph node metastasis\nN1 Regional lymph node metastasis\n\n
\nPrimary Tumor (T)\nT2a Anterior orbital involvement (+/- conjunctival involvement)\nT2b Anterior orbital involvement (+/- conjunctival involvement + lacrimal\n involvement)\nT2c Posterior orbital involvement (+/- conjunctival involvement +/-\n anterior involvement and +/- any extraocular muscle involvement)\nT2d Nasolacrimal drainage system involvement (+/- conjunctival\n involvement but not including nasopharynx)\nT3 Lymphoma with pre-septal eyelid involvement (defined above) +/-\n orbital involvement +/- any conjunctival involvement\nT4 Orbital adnexal lymphoma extending beyond orbit to adjacent\n \n structures such as bone and brain\nT4a Involvement of nasopharynx\nT4b Osseous involvement (including periosteum)\nT4c Involvement of maxillofacial, ethmoidal and/or frontal sinuses\nT4d Intracranial spread\nTX Lymphoma extent not specified\nT0 No evidence of lymphoma\nT1 Lymphoma involving the conjunctiva alone without orbital involvement\nT1a Bulbar conjunctiva only\nT1b Palpebral conjunctiva +/- fornix +/- caruncle\nT1c Extensive conjunctival involvement\nT2 Lymphoma with orbital involvement +/- any conjunctival involvement\n\n
\nRegional Lymph Nodes (N)\n \nNX Regional lymph nodes cannot be assessed\nN0 No evidence of lymph node involvement\nN1 Involvement of ipsilateral regional lymph nodes\nN2 Involvement of contra lateral or bilateral regional lymph nodes\nN3 Involvement of peripheral lymph nodes not draining ocular adnexal\n region\nN4 Involvement of central lymph nodes\n\n
\nDistant Metastasis (M)\n \nM0 No evidence of involvement of other extranodal sites\nM1a Noncontiguous involvement of tissues or organs external to the ocular\n adnexa (e.g., parotid glands, submandibular gland, lung, liver,\n spleen, kidney, breast, etc.)\nM1b Lymphomatous involvement of the bone marrow\nM1c Both M1a and M1b involvement\n\n