\nNo evidence of primary tumor\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\nMediastinal (excluding superior mediastinal node(s), Level VII, see EOD\n Regional Nodes)\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nInvasive tumor confined to one of the following subsites\n Inferior wall (superior surface of soft palate)\n Lateral wall\n Posterior superior wall (vault)\nInvolvement of two or more subsites\n Lateral wall extending into eustachian tube/middle ear\n Posterior, inferior, or lateral wall(s)\nConfined to nasopharynx, NOS\nLocalized, NOS\n\n
\nNasal cavity WITHOUT pharyngeal extension\n Oropharynx\n Soft palate, inferior surface including uvula WITHOUT pharyngeal\n extension\n Soft tissue, NOS (excluding soft tissue of neck)\n\n
\nAny site listed in codes 100 or 200\n WITH fixation or tumor described only as FIXED with parapharyngeal\n extension\nAdjacent soft tissue involvement\n Lateral pterygoid\n Medial pterygoid\n Parapharyngeal space\n Prevertebral muscles\n Pterygopalatine fossa WITHOUT bone invasion\n\n
\nBone, NOS\n Bony structures of skull base\n Cartilage, NOS\n Cervical vertebra\n Floor of orbit\n Hard palate\n Paranasal sinuses\n Pterygoid structures\n Skull base\n\n
\nBrain\n Cranial nerve involvement\n Hypopharynx\n Infratemporal fossa/masticator space\n Intracranial extension, NOS\n Orbit except bone of floor of orbit\n Parotid gland\n Soft tissues of neck\n\n
\nNo evidence of primary tumor\n No tumor identified, but EBV-positive cervical node(s) involvement\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nCervical lymph node(s), unilateral, 6 cm or smaller\nRetropharyngeal lymph node(s), unilateral or bilateral, 6 cm or smaller\n above the caudal border of cricoid cartilage\n\n
\nCervical lymph node(s), bilateral, 6 cm or smaller\n above the caudal border of cricoid cartilage\n\n
\nCervical lymph node(s), unilateral or bilateral, greater than 6 cm\n AND/OR extension below the caudal border of cricoid cartilage\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Axilla\n Groin\n Infraclavicular\n Mediastinal (excluding superior mediastinal nodes)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nLymphoma involving the conjunctiva alone\n WITHOUT eyelid or orbital involvement\n\n
\nLymphoma involving the conjunctiva alone\n UNKNOWN if eyelid or orbital involvement\n\n
\nLymphoma with orbital involvement\n WITH or WITHOUT conjunctival involvement\n\n
\nLymphoma with preseptal eyelid involvement\n WITH or WITHOUT orbital or conjunctival involvement\n\n
\nOrbital adnexal lymphoma AND extraorbital lymphoma\n extending beyond the orbit to adjacent structures\n Bone\n Brain\n Maxillofacial sinuses\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nSINGLE lymph node region superior to the mediastinum\n\n
\nMULTIPLE lymph node regions superior to the mediastinum\n\n
\nUnknown number of lymph node region(s)\n OR regions draining the ocular adnexal structures\n and superior to the mediastinum\n\n
\nMediastinal\n\n
\nDiffuse OR disseminated involvement of peripheral and central\n lymph node regions\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo involvement of extranodal sites\n\n
\nNon-contiguous involvement of tissues or organs external to the\n Spleen\n Submandibular gland\n ocular adnexa (excluding bone marrow), including but not limited to\n Breast\n Gastrointestinal tract\n Kidney\n Liver\n Lung\n Parotid gland\n Salivary gland\n\n
\nBone marrow\n\n
\nAny site listed in code 10 plus involvement of bone marrow (code 30)\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n\n
\nConfined to tissue or organ of origin\nIntraocular extension\nLocalized, NOS\n\n
\nAdjacent extraocular extension\n Eyelid\n Orbit\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nCervical NOS\n Mandibular\n Submandibular (submaxillary)\nParotid, NOS\n Infra-auricular\n Preauricular\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nBenign or borderline brain tumor\n\n
\nInfratentorial tumor confined to\nThalamus\nInfratentorial tumor\nBoth cerebellum and brain stem involved with tumor on one side\nSupratentorial tumor confined to\nCerebral hemisphere (cerebrum) or meninges of cerebral hemisphere\n (one side) frontal lobe\nOccipital lobe\nParietal lobe\nTemporal lobe\nConfined to ventricles\n \n Tumor invades or encroaches upon ventricular system\nConfined to brain, NOS\n Confined to meninges, NOS\nBrain stem or meninges of brain stem (one side) Medulla oblongata\nMidbrain (mesencephalon)\nPons\nCerebellum or meninges of cerebellum (one side or midline) Lateral lobes\nMedian lobe of cerebellum\nVermis\nHypothalamus\n\n
\nTumor crosses the midline\n \nSupratentorial tumor extends infratentorially to involve\nBrain stem\nCerebellum\nHypothalamus\nPallium\nPosterior cranial fossa\nThalamus\n \nInfratentorial tumor extends supratentorially to involve\n \nCerebrum (cerebral hemisphere) (excluding hypothalamus, pallium, thalamus)\nAnterior cranial fossa\nCorpus callosum\nMiddle cranial fossa\nSuprasellar brain\nTapetum\nBone (skull)\n Contralateral hemisphere\n Corpus callosum (including splenium)\n Major blood vessel(s)\n Meninges (e.g., dura)\n Nerves (cranial, NOS)\n Spinal cord/canal\n\n
\nCirculating cells in cerebral spinal fluid (CSF)\n \nNasal cavity\n Nasopharynx\n Other direct extension outside CNS\n Posterior pharynx\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNot applicable: Information not collected for this schema\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n\n
\nMetastasis within CNS and CSF pathways\n "Drop" metastasis\nMetastasis outside the CNS\n Extra-neural metastasis\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nBenign or borderline brain\n\n
\nConfined to tissue or site of origin\n Localized, NOS\n\n
\nAdjacent connective/soft tissue\n Adjacent muscle\n Brain for cranial nerve tumor(s)\n Major blood vessel(s)\n Meningeal tumor infiltrates nerve\n Nerve tumor infiltrates meninges (dura)\n Sphenoid and frontal sinuses (skull)\n\n
\nBone other than skull\n Brain except for cranial nerve tumor(s)\n Eye\n \nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNot applicable: Information not collected for this schema\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nBenign or borderline tumor\n\n
\nInvasive tumor confined to gland of origin\nLocalized, NOS\n\n
\nAdjacent connective/soft tissue\nAdjacent organ(s)/structure(s) for pituitary and craniopharyngeal duct\n Cavernous sinus\n Infundibulum\n Pons\n Sphenoid body and sinuses\n Adjacent organ(s)/structure(s) for pineal\n Infratentorial and central brain\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNot applicable: Information not collected for this schema\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nSingle invasive tumor confined/limited to thyroid\nMultiple foci confined/limited to thyroid\nInto thyroid capsule, but not beyond\nConfined/limited to thyroid, NOS\nLocalized, NOS\n\n
\nMicroscopic extrathyroidal extension\nExtrathyroidal extension, NOS\n\n
\nGross extrathyroidal extension invading\n Pericapsular soft tissue/connective tissue\n Strap muscle(s) \n Omohyoid\n Sternohyoid\n Sternothyroid\n Thyrohyoid\n\n
\nGross extrathyroidal extension invading\n Vagus nerve\n Cricoid cartilage\n Esophagus\n Larynx\n Parathyroid\n Recurrent laryngeal nerve\n Sternocleidomastoid muscle\n Subcutaneous soft tissues\n Trachea\n\n
\nGross extrathyroidal extension invading\n Blood vessel(s) (major) \n Carotid artery (encased)\n Jugular vein\n Thyroid artery or vein\n Thyroid cartilage\n Tumor described as "FIXED to adjacent tissues"\n\n
\nGross extrathyroidal extension invading\n Bone\n Mediastinal tissues\n Prevertebral fascia\n Skeletal muscle, other than strap or sternocleidomastoid muscle\nFurther contiguous extension\n\n
\nGross extrathyroidal extension, NOS\n\n
\nNo evidence of primary tumor\n\n
\nNo regional lymph node involvement\n CYTOLOGICALLY or HISTOLOGICALLY confirmed to be benign node(s)\n\n
\nNo regional lymph node involvement\n RADIOLOGICALLY or CLINICALLY confirmed\n\n
\nNo regional lymph node involvement\n UNKNOWN how confirmed\n\n
\nLevel VI nodes - Anterior compartment group (central compartment)\nLevel VII nodes-Superior mediastinal group (for other mediastinal node(s)\nsee EOD Mets)\n Esophageal grove\n Paratracheal - below suprasternal notch\n Pretracheal - below suprasternal notch\n Laterotracheal\n Paralaryngeal\n Paratracheal - above suprasternal notch\n Perithyroidal\n Precricoid (Delphian)\n Prelaryngeal\n Pretracheal - above suprasternal notch\n Recurrent laryngeal\n\n
\nUnilateral, bilateral, or contralateral lymph nodes\n Infraauricular\n Intraparotid\n Periparotid\n Preauricular\nLevel II - Upper jugular\n Jugulodigastric (subdigastric)\n Upper deep cervical\nLevel II A - Anterior\nLevel II B - Posterior\nLevel III - Middle jugular\nLevel I\n Middle deep cervical\nLevel IV - Lower jugular\n Jugulo-omohyoid (supraomohyoid)\n Lower deep cervical\n Level VB - Transverse cervical, supraclavicular\nLevel V - Posterior triangle group\n Posterior cervical\n Level VA - Spinal accessory\nOther Groups\n Parapharyngeal\nLevel IA - Submental\n Retroauricular (mastoid)\n Retropharyngeal\n Suboccipital\nCervical, NOS\nDeep cervical, NOS\nInternal jugular, NOS\nLevel IB - Submandibular (submaxillary), sublingual\nFacial\n Buccinator\n Mandibular\n Nasolabial\nParotid\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nModerately advanced disease WITH gross extrathyroidal extension invading\n Vagus nerve\n Cricoid cartilage\n Esophagus\n Larynx\n Parathyroid\n Recurrent laryngeal nerve\n Sternocleidomastoid muscle\n Subcutaneous soft tissues\n Trachea\n\n
\nSingle invasive tumor confined/limited to thyroid\nMultiple foci confined/limited to thyroid\nInto thyroid capsule, but not beyond\nConfined/limited to thyroid, NOS\nLocalized, NOS\n\n
\nMicroscopic extrathyroidal extension\nExtrathyroidal extension, NOS\n\n
\nGross extrathyroidal extension invading\n Pericapsular soft tissue/connective tissue\n Strap muscle(s) \n Omohyoid\n Sternohyoid\n Sternothyroid\n Thyrohyoid\n\n
\nVery advanced disease invading\n Blood vessel(s) (major) \n Carotid artery (encased)\n Jugular vein\n Thyroid artery or vein\n Thyroid cartilage\n Tumor described as "FIXED to adjacent tissues"\n\n
\nVery advanced disease invading\n Bone\n Mediastinal tissues\n Prevertebral fascia\n Skeletal muscle, other than strap or sternocleidomastoid muscle\nFurther contiguous extension\n\n
\nAdvanced disease, NOS\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\nCYTOLOGICALLY or HISTOLOGICALLY confirmed to be benign node(s)\n\n
\nNo regional lymph node involvement\n RADIOLOGICALLY or CLINICALLY confirmed\n\n
\nNo regional lymph node involvement\n UNKNOWN how confirmed\n\n
\nUnilateral or bilateral lymph nodes\n Recurrent laryngeal\nLevel VII nodes-Superior mediastinal group (for other mediastinal\n node(s) see EOD Mets)\n Esophageal groove\n Paratracheal - below suprasternal notch\n Pretracheal - below suprasternal notch\nLevel VI nodes - Anterior compartment group\n Laterotracheal\n Paralaryngeal\n Paratracheal - above suprasternal notch\n Perithyroidal\n Precricoid (Delphian)\n Prelaryngeal\n Pretracheal - above suprasternal notch\n\n
\nUnilateral, bilateral, or contralateral lymph nodes\n Infraauricular\n Intraparotid\n Periparotid\n Preauricular\nLevel II - Upper jugular\n Jugulodigastric (subdigastric)\n Upper deep cervical\n Level II A - Anterior\n Level II B - Posterior\nLevel III - Middle jugular\nLevel I\n Middle deep cervical\nLevel IV - Lower jugular\n Jugulo-omohyoid (supraomohyoid)\n Lower deep cervical\n Level VB - Transverse cervical, supraclavicular\nLevel V - Posterior triangle group\n Posterior cervical\n Level VA - Spinal accessory\nOther Groups\n Parapharyngeal\n Level IA - Submental\n Retroauricular (mastoid)\n Retropharyngeal\n Suboccipital\nCervical, NOS\nDeep cervical, NOS\nInternal jugular, NOS\n Level IB - Submandibular (submaxillary), sublingual\nFacial\n Buccinator\n Mandibular\n Nasolabial\nParotid\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nAtypical parathyroid neoplasm\n (neoplasm of uncertain malignant potential)\n\n
\nConfined to parathyroid\n Extension to soft tissue\nLocalized, NOS\n\n
\nInvasion into thyroid gland\n\n
\nAdjacent lymph node(s)\n Esophagus\n Recurrent laryngeal nerve\n Thymus\n Trachea\n Skeletal muscle\n\n
\nMajor blood vessels\n Spine\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nLevel VI - Anterior compartment group\nLevel VII - Superior mediastinal group (for other mediastinal node(s), see\n EOD Mets)\n Esophageal groove\n Paratracheal - below suprasternal notch\n Pretracheal - below suprasternal notch\n Laterotracheal\n Paralaryngeal\n Paratracheal - above suprasternal notch\n Perithyroidal\n Precricoid (Delphian)\n Prelaryngeal\n Pretracheal - above suprasternal notch\n Recurrent laryngeal\n\n
\nUnilateral, bilateral or contralateral nodes\nLevel III - Middle jugular\n Middle deep cervical\nLevel IV - Lower jugular\n Jugulo-omohyoid (supraomohyoid)\n Lower deep cervical\n Virchow node\nLevel V - Posterior triangle group\n Posterior cervical\n Level VA - Spinal accessory\n Level VB - Transverse cervical, supraclavicular\nLevel I\nOther groups\n Cervical, NOS\n Deep cervical, NOS\n Facial \n Buccinator (buccal)\n Mandibular\n Nasolabial\n Internal jugular, NOS\n Parapharyngeal\n Parotid \n Level IA - Submental\n Infraauricular\n Intraparotid\n Periparotid\n Preauricular\n Retroauricular (mastoid)\n Retropharyngeal\n Suboccipital\n Level IB - Submandibular (submaxillary), sublingual\nLevel II - Upper jugular\n Jugulodigastric (subdigastric)\n Level IIA - Anterior\n Level IIB - Posterior\n Upper deep cervical\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n\n
\nAny size tumor, no extra-adrenal invasion\n Confined to adrenal gland\nLocalized, NOS\n\n
\nAny size tumor with local invasion\nAdjacent connective tissue\nGerota's fascia\n\n
\nInvasion of adjacent organs\nBlood vessels (large) Renal vein\nVena cava\nKidney\nRetroperitoneal structures including Great vessels Aorta\nInferior vena cava\n\n
\nDiaphragm\n Liver\n Pancreas\n Spleen\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nAortic, NOS\n Para-aortic\n Periaortic\nPericaval, NOS\n Paracaval\n Precaval\n Retrocaval\nRetroperitoneal, NOS\n\n
\nRegional lymph node(s), NOS\nLymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n\n
\nAny size pheochromocytoma (PH) tumor, no extra-adrenal invasion\nConfined to adrenal gland\nLocalized, NOS\n\n
\nAny size paraganglioma (PG) tumor, no extra-adrenal invasion\n\n
\nAdjacent connective tissue\n Aorta\n Inferior vena cava\nGerota's fascia\nInvasion of adjacent organs\n Blood vessels (large) \n Renal vein\n Vena cava\n Kidney\n Retroperitoneal structures including \n Great vessels \n\n
\nDiaphragm\nLiver\nPancreas\nSpleen\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nAortic, NOS\n Para-aortic\n Periaortic\nPericaval, NOS\n Paracaval\n Precaval\n Retrocaval\nRetroperitoneal, NOS\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nBone\n\n
\nDistant lymph node(s), NOS\n\n
\nLiver\nLung\n\n
\nAny combination of codes 10, 20, 30\nOther distant metastasis\nCarcinomatosis\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nAny size tumor with extension to\n Adenoid\n Nasopharynx (inferior wall, superior surface of soft palate)\n Pharyngeal tonsil (nasopharyngeal tonsil)\n Posterior superior wall (vault)\nSoft Palate (C051, C052)\n Invasion of \n Lamina propria, submucosa, musculature\n Tumor crosses midline\nTongue Base (C019, C024)\n Invasion of \nAll sites\n Lamina propria, submucosa, musculature (intrinsic)\n Tumor crosses midline\n Confined to site of origin\n Localized, NOS\nOropharynx (C090-C091, C098-C099, C100, C102-C104, C108-C109)\n Tonsil (palatine, NOS)\n Tonsillar pillar/fossa\n Wall (anterior [including vallecula], lateral, posterior)\nPharyngeal Tonsil (C111)\n\n
\nAny size tumor with extension to\nPharyngeal Tonsil (C111)\n Nasal cavity\n Oropharynx\n Pterygopalatine fossa\n Soft palate, inferior surface including uvula\nSoft Palate (C051, C052)\n Buccal mucosa (inner cheek)\n Gum (gingiva), upper\n Lateral pharyngeal wall\n Tonsils, including tonsillar pillars and fossae\nOropharynx (C090-C091, C098-C099, C100, C102-C104, C108-C109)\nTongue Base (C019, C024)\n Anterior two-thirds of tongue for base of tongue\n Base of tongue for lingual tonsil\n Floor of mouth\n Glossoepiglottic fold\n Glossopharyngeal fold\n Lateral pharyngeal wall\n Lingual tonsil for base of tongue\n Lower gingiva\n Pharyngoepiglottic fold\n Base of tongue (including lingual tonsil)\n Soft palate, inferior surface or NOS including uvula\n Sublingual gland\n Tonsil, tonsillar pillars and fossae\n Buccal mucosa\n Floor of mouth\n Gum (gingiva)\n Lateral walls (both) through soft palate or base of tongue\n Soft palate (inferior surface including uvula, superior [nasopharyngeal]\n surface, NOS)\n\n
\nEpiglottis, lingual surface\n\n
\nEpiglottis, lingual surface plus both lateral walls through soft\n palate or base of tongue\nEpiglottis WITH fixation\n\n
\nOropharynx (C090-C091, C098-C099, C100, C102-C104, C108-C109)\n Mandible\n Paranasal sinuses\nSoft Palate (C051, C052)\n Hard palate\n Mandible\n Hypopharynx, NOS\n Larynx, NOS\n Posterior surface of epiglottis\n Prevertebral fascia/muscle\n Pyriform sinus\n Soft tissue of neck\nPharyngeal Tonsil (C111)\n Hard palate\n\n
\nAll sites\n Masticator space \n Cranial nerve V-third division\n Muscles of mastication\n Pterygoid muscle (lateral, medial, NOS)\n Ramus of mandible\n Temporalis muscles\n Parapharyngeal extension (pharyngeal space invasion)\n Pterygoid plates\n Skull (base, bone, NOS)\nFurther contiguous extension\n Carotid artery (encasing)\nOropharynx (C090-C091, C098-C099, C100, C102-C104, C108-C109)\n Anterior 2/3 of tongue\n Hard palate\n Mandible\n Parotid gland\nPharyngeal Tonsil (C111)\n Brain\n Cranial nerve involvement\n Hypopharynx\n Infratemporal fossa/masticator space\n Deep/extrinsic muscles of tongue \n Orbit (floor, NOS)\n Paranasal sinus\n Soft tissues of neck\nSoft Palate (C051, C052)\n Hypopharynx\n Maxilla\n Maxillary sinus (antrum)\n Nasal cavity\n Nasopharynx (lateral, NOS)\n Palatine bone (bone of hard palate)\n Genioglossus\n Tongue\nTongue Base (C019, C024)\n Hard palate\n Hypopharynx\n Larynx\n Mandible\n Skin\n Hyoglossus\n Palatoglossus\n Styloglossus\n Lateral nasopharynx\n Masseter muscle\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nClinical evaluation only\n Ipsilateral regional lymph node(s)\n\n
\nClinical evaluation only\n Bilateral or contralateral regional lymph node(s)\n\n
\nPathological evaluation only\n Regional lymph node(s) involved\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII,\n see EOD Regional Nodes)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n\n
\nInvasive tumor confined to gland of origin\nLocalized, NOS\n\n
\nAdjacent connective tissue\nAdjacent organ(s)/structure(s)\n Aortic Body\n Organ(s)/structure(s) in mediastinum\n Carotid body\n Upper neck\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nCervical for carotid body\n Mediastinal for aortic body\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certicate Only\n\n
\nNodal lymphomas\n Single lymph node region involved\n Involvement of multiple nodal chains in the SAME lymph node region\n\n
\nDiffuse or disseminated\n Peripheral blood involvement WITH other involvement\nDistant metastasis, NOS\n Bone\n Central nervous system (CNS)\n Any involvement of\n Bone marrow\n Cerebrospinal fluid (CSF)\n Liver\n Lung, multiple lesions (other than by direct extension\n in code 400)\n\n
\nUnknown; extension not stated\nPrimary tumor cannot be assessed\nNot documented in medical record\nDeath Certificate Only\n\n
\nExtranodal lymphomas\n Single extralymphatic site\n WITHOUT nodal involvement\n Multifocal involvement (except multifocal lung involvement, see\n code 800) of one extralymphatic organ/site\n WITHOUT nodal involvement (see code 400 for WITH nodal involvement)\n\n
\nNodal lymphomas\n Two or more lymph node regions involved\n SAME side of diaphragm\n\n
\nNodal lymphomas\n Localized involvement of a single extralymphatic organ/site\n WITH involvement of its regional lymph node(s) OR\n WITH involvement of other lymph node(s) on the SAME side\nExtranodal lymphomas\n of the diaphragm\n Contiguous extralymphatic extension from nodal/lymphatic site\n WITH or WITHOUT involvement of other nodal regions\n on SAME side of diaphragm\n\n
\nCodes 300 or 400 with bulky disease\n\n
\nNodal and Extranodal lymphomas\n Involvement of lymph node regions on BOTH sides of the diaphragm\n WITHOUT or UNKNOWN spleen involvement\n\n
\nNodal and Extranodal lymphomas\n Involvement of lymph node regions on BOTH sides of the diaphragm WITH\n spleen involvement\n Includes involvement of lymph nodes ABOVE the diaphragm WITH spleen\n involvement\n\n
\nDiffuse or disseminated involvement (except multifocal lung\n 800) of one extralymphatic organ/site\nWITH nodal involvement\nNoncontiguous extralymphatic organ involvement in conjunction\nwith nodal disease (two or more\n sites involved)\n involvement or any liver involvement,\n see code 800) of ONE OR MORE extralymphatic organ(s)/site(s)\n WITH or WITHOUT nodal involvement\nInvolvement of isolated extralymphatic organ in absence of\n involvement of adjacent lymph nodes,\n but in conjunction with disease in distant sites\nMultifocal involvement (except multifocal lung involvement or\n any liver involvement, see code\n\n
\nPeripheral blood involvement ONLY\n\n
\nNot applicable: Information not collected for this schema\n\n
\nNot applicable: Information not collected for this schema\n\n
\nSingle lymph node region involved\nInvolvement of multiple nodal chains in the SAME lymph node region\n\n
\nDiffuse or disseminated (multifocal involvement) of\n Peripheral blood involvement WITH other involvement\nDistant metastasis, NOS\n Bone\n Central nervous system (CNS)\nAny involvement of\n Bone marrow\n Cerebrospinal fluid (CSF)\n Liver\n Lung, multiple lesions (other than by direct\n extension in code 400)\n\n
\nUnknown; extension not stated\nPrimary tumor cannot be assessed\nNot documented in medical record\nDeath Certificate Only\n\n
\nSingle extralymphatic site\n WITHOUT nodal involvement\nMultifocal involvement (except multifocal lung involvement, see\n codes 700 or 800) of one extralymphatic organ/site\n WITHOUT nodal involvement\n\n
\nTwo or more lymph node regions involved\n SAME side of diaphragm\n\n
\nLocalized involvement of a single extralymphatic organ/site\n WITH involvement of its regional lymph node(s) OR\n WITH involvement of other lymph node(s) on the SAME side\n of the diaphragm\nContiguous extralymphatic extension from nodal/lymphatic site\n WITH or WITHOUT involvement of other nodal regions\n on SAME side of diaphragm\n\n
\nCodes 300 or 400 with bulky disease\n\n
\nNodal and Extranodal lymphomas\n Involvement of lymph node regions on BOTH\n sides of the diaphragm\n WITHOUT or UNKNOWN spleen involvement\n\n
\nNodal and Extranodal lymphomas\n Involvement of lymph node regions on BOTH sides\n of the diaphragm WITH spleen involvement\n Includes involvement of lymph nodes ABOVE the\n diaphragm WITH spleen involvement\n\n
\nDiffuse or disseminated involvement (except multifocal\n extralymphatic organ/site\nWITH nodal involvement\nNoncontiguous extralymphatic organ involvement in conjunction\n with nodal disease (two or more sites involved)\n lung involvement or any liver involvement, see code 800)\n of ONE OR MORE extralymphatic organ(s)/site(s)\n WITH or WITHOUT nodal involvement\nInvolvement of isolated extralymphatic organ in absence of\n involvement of adjacent lymph nodes, but in conjunction\n with disease in distant sites\nMultifocal involvement (except multifocal lung involvement\n or any liver involvement, see code 800) of one\n\n
\nPeripheral blood involvement ONLY\n\n
\nNot applicable: Information not collected for this schema\n\n
\nNot applicable: Information not collected for this schema\n\n
\nLess than 10% of skin surface, no tumors\n Patches only\n\n
\nGeneralized erythroderma (confluence of erythemia)\n(Greater than or equal to 80% body surface involved with\n diffuse redness)\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nLess than 10% of skin surface, no tumors\n Papules or plaques WITH or WITHOUT patches\n\n
\nSkin involvement less than 10% OR unknown % of skin involvement\n AND not stated whether patches, papules or plaques\n AND no tumors\nLimited skin involvement\nLocalized, NOS\nMFCG Stage I\n\n
\nGreater than or equal to 10% of skin surface, no tumors\n Patches only\n\n
\nGreater than or equal to 10% of skin surface, no tumors\n Plaques or papules WITH or WITHOUT patches\n\n
\nSkin involvement greater than or equal to 10%\nGeneralized plaques/patches OR\nNot stated whether patches, papules or plaques\nNo tumors\nMFCG Stage II\n\n
\nGeneralized erythroderma (confluence of erythemia)\n(Greater than 50% and less than 80% body surface involved with\n diffuse redness)\n\n
\nSkin lesion described as tumor less than 1 cm\n\n
\nOne or more tumors equal to 1 cm or greater\n Cutaneous tumor, size not stated\nMFCG Stage III\n\n
\nNo regional lymph node involvement\n No clinically abnormal peripheral lymph nodes, no biopsy required\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\nDistant lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nClinically enlarged palpable peripheral lymph node(s) (adenopathy)\n WITH pathologically negative nodes OR\n WITHOUT histologic confirmation\n\n
\nClinically abnormal peripheral lymph nodes\n Pathologically Dutch grade 1 or NCI LN 0-2\n Clone negative\n\n
\nClinically abnormal peripheral lymph nodes\n Pathologically Dutch grade 1 or NCI LN 0-2\n Clone positive\n\n
\nClinically abnormal peripheral lymph nodes\n Pathologically Dutch grade 1 or NCI LN 0-2\n Clone unknown OR\nDutch grade and NCI LN grade unknown\n Clone positive, negative, or unknown\n\n
\nClinically abnormal peripheral lymph nodes\n Pathologically Dutch grade 2 or NCI LN 3\n Clone negative\n\n
\nClinically abnormal peripheral lymph nodes\n Pathologically Dutch grade 2 or NCI LN 3\n Clone positive\n\n
\nClinically abnormal peripheral lymph nodes\n Pathologically Dutch grade 2 or NCI LN 3\n Clone unknown\n\n
\nClinically abnormal peripheral lymph nodes\n Pathologically Dutch grades 3-4 or NCI LN 4\n Clone positive or negative or unknown\nCentral nodes\n Pathologically Dutch grades 3-4 or NCI LN 4\n Clone positive, negative, or unknown\n\n
\nNo visceral organ involvement\nNo distant metastases\nUnknown if distant metastases\nClinical confirmation only of visceral (non-cutaneous, extranodal)\n involvement\n Except for liver and spleen imaging, see code 10\n\n
\nCarcinomatosis, CLINICAL or UNKNOWN confirmation\n\n
\nDistant site(s) involved\nFurther contiguous spread\nImaging confirmation of metastasis\n Bone marrow\n Liver\n Non-visceral organs/sites\n Spleen\nVisceral (non-cutaneous, extranodal) involvement, pathologically confirmed\nInvolvement by at least one visceral organ outside the skin, nodes,\n or bone marrow\n\n
\nDeath Certificate Only\n\n
\nSolitary lesion\n Solitary skin involvement\n\n
\nRegional skin involvement\n Multiple lesions confined to one or two contiguous body regions\n\n
\nMultiple lesions involving 2 noncontiguous body regions\n\n
\nMultiple lesions involving >=3 body regions\n\n
\nGeneralized skin involvement\n Multiple lesions confined to three or more contiguous body regions\n Multiple lesions confined to discontiguous body regions\n\n
\nMultiple lesions, NOS\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nPeripheral node region that drains an area of current or\n skin involvement\n\n
\nTwo or more peripheral node regions\n OR involvement of any lymph node region that does not drain\n an area of current or prior skin involvement\n\n
\nCenrowal nodes\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastases\n Unknown if distant metastases\n\n
\nDistant lymph node(s), NOS\n\n
\nDistant site(s) involved\nExtracutaneous non-lymph node disease present\nVisceral (non-cutaneous) metastasis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nCarcinomatosis\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nMultiple myeloma (9732)\n Myeloma, NOS (9732)\n Plasma cell myeloma (9732)\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNot applicable: Information not collected for this schema\n\n
\nNot applicable: Information not collected for this schema\n\n
\nSingle plasmacytoma occurring in bone (osseous or medullary) (9731)\n Single plasmacytoma, NOS (9731)\nWITH or WITHOUT soft tissue extension\n\n
\nSingle plasmacytoma (9734)\n Single plasmacytoma occurring outside of bone (extraosseous or\n extramedullahry) (9734)\n\n
\nMultiple plasmacytomas (9731, 9734)\n Multiple osseous or medullary plasmacytomas (9731)\n Multiple extraosseous or extramedullary plasmacytomas (9734)\n\n
\nLymphoplasmacytic lymphoma (9671)\n Waldenstrom Macroglobulinemia (9761)\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nExtraosseous plasmacytomas only (9734)\n Regional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nNot applicable\n Lymphoplasmacytic lymphoma (9671)\n Plasmacytoma, NOS (9731)\n Single plasmacytoma occurring in bone (osseous or medullary) (9731)\n Waldenstrom Macroglobulinemia (9761)\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNot applicable: Information not collected for this schema\n\n
\nLocalized disease\n (Single/solitary/unifocal/isolated)\n\n
\nSystemic disease\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNot applicable: Information not collected for this schema\n\n
\nNot applicable: Information not collected for this schema\n\n
\nNot applicable: Information not collected for this schema\n\n
\nNot applicable: Information not collected for this schema\n\n
\nNot applicable: Information not collected for this schema\n\n
\nIn situ, intraepithelial, noninvasive, preinvasive\nCancer in situ WITH endocervical gland involvement\n \nCervical intraepithelial neoplasia (CIN) Grade III\n\n
\nInvasion beyond uterus, NOS\n \nFIGO Stage II [NOS]\n\n
\nBladder wall\nFIGO Stage IIIA\nBladder, NOS excluding mucosa\nBullous edema of bladder mucosa\nRectal wall\nRectum, NOS excluding mucosa\nUreter, intra- and extramural\nVagina, lower third (not extending to pelvic wall)\nVulva\n \n\n
\nDescribed clinically as frozen pelvis\nHydronephrosis or nonfunctioning kidney\nPelvic wall(s)\n \nFIGO Stage IIIB\n\n
\nFallopian tube(s)\nOvary(ies)\nUrethra\n \nFIGO Stage III [NOS]\n\n
\nBladder mucosa (for bullous edema of bladder mucosa, see code 550)\nRectal mucosa\nSigmoid colon\nSmall intestine\n \nFIGO Stage IVA\n \nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\nPrimary tumor cannot be assessed\nNot documented in patient record\n \nDeath Certificate Only\n\n
\nNot clinically visible (diagnosed only by microscopy)\nMeasured stromal invasion less than or equal to 3.0 mm\n \nFIGO Stage IA1\n\n
\nNot clinically visible (diagnosed only by microscopy)\n \nMeasured stromal invasion 3.1 mm to 5.0 mm\n \nFIGO Stage IA2\n\n
\nNot clinically visible (diagnosed only by microscopy)\nMeasured stromal invasion less than or equal to 5.0 mm\n \nFIGO Stage IA [NOS]\n\n
\nConfined to cervix AND\nMeasured stromal invasion greater than 5.0 mm\n \nFIGO Stage IB1, IB2, IB3\n\n
\nLocalized, NOS\nConfined to cervix uteri or uterus, NOS, except corpus uteri, NOS\n \nFIGO Stage IB [NOS]\n\n
\nCorpus uteri, NOS\nConfined to corpus uteri, size, depth and horizontal spread unknown\n \nFIGO Stage I [NOS]\n\n
\nAny size tumor WITHOUT parametrial (paracervical soft tissue) invasion\n Cul de sac (rectouterine pouch)\n Upper two-thirds of vagina including fornices\n Vagina, NOS\n Vaginal wall, NOS\nFIGO Stage IIA (IIA1, IIA2, IIA NOS)\n\n
\nLigament(s) (broad, cardinal, uterosacral)\nParametrial (paracervical soft tissue) invasion\n \nFIGO Stage IIB\n\n
\nNo regional lymph node involvement\n\n
\nUnknown; regional lymph node(s) not stated\nRegional lymph node(s) cannot be assessed\nNot documented in patient record\n \nDeath Certificate Only\n\n
\nIsolated tumor cells\n \n Lymph node metastasis less than or equal to 0.2 mm\n\n
\nPelvic lymph nodes\n \n Lymph node metastasis greater than 0.2 mm but not greater than 2.0 mm \n in diameter\n\n
\nPelvic lymph nodes\n \n Lymph node metastasis greater than 2.0 mm in diameter\n\n
\nPelvic lymph nodes\n \n Size of lymph node metastasis unknown\n\n
\nParaaortic lymph nodes\n \n Lymph node metastasis greater than 0.2 mm but not greater than 2.0 mm\n in diameter\n WITH or WITHOUT pelvic lymph nodes\n\n
\nParaaortic lymph nodes\n \n Lymph node metastasis greater than 2.0 mm in diameter\n WITH or WITHOUT pelvic lymph nodes\n\n
\nParaaortic lymph nodes\n \n Size of lymph node metastasis unknown\n WITH or WITHOUT pelvic lymph nodes\n\n
\nRegional lymph node(s), NOS\nLymph node(s), NOS\n\n
\nNo distant metastasis\nUnknown if distant metastasis\n\n
\nDistant lymph node(s)\n \n Inguinal (femoral)\n Mediastinal\n Scalene\n Supraclavicular\n Distant lymph node(s), NOS\n\n
\nDistant metastasis\n \nDistant metastasis WITH or WITHOUT distant lymph node(s)\n \nDistant metastasis, NOS\n \nFIGO Stage IVB\n \n Adnexa\n Bone\n Liver\n Lung\n Peritoneal spread\n Uterine serosa\n Carcinomatosis\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nAny size tumor with extension to\nPharyngeal Tonsil (C111)\n Adenoid\n Nasopharynx (inferior wall, superior surface of soft palate)\n Pharyngeal tonsil (nasopharyngeal tonsil)\n Posterior superior wall (vault)\nSoft Palate (C051, C052)\n Invasion of \n Lamina propria, submucosa, musculature\n Tumor crosses midline\nTongue Base (C019, C024)\nAll sites\n Invasion of \n Lamina propria, submucosa, musculature (intrinsic)\n Tumor crosses midline\n Confined to site of origin\n Localized, NOS\nOropharynx (C090-C091, C098-C099, C100, C102-C104, C108-C109)\n Base of tongue (including Lingual tonsil)\n Tonsil (palatine, NOS)\n Tonsillar pillar/fossa\n Wall (anterior [including vallecula], lateral, posterior)\n\n
\nAny size tumor with extension to\n Nasal cavity\n Oropharynx\n Pterygopalatine fossa\n Soft palate, inferior surface including uvula\nSoft Palate (C051, C052)\n Buccal mucosa (inner cheek)\n Gum (gingiva), upper\n Lateral pharyngeal wall\n Tonsils, including tonsillar pillars and fossae\nTongue Base (C019, C024)\nOropharynx (C090-C091, C098-C099, C100, C102-C104, C108-C109)\n Anterior two-thirds of tongue for base of tongue\n Base of tongue for lingual tonsil\n Floor of mouth\n Glossoepiglottic fold\n Glossopharyngeal fold\n Lateral pharyngeal wall\n Lingual tonsil for base of tongue\n Lower gingiva\n Pharyngoepiglottic fold\n Soft palate, inferior surface or NOS including uvula\n Buccal mucosa\n Sublingual gland\n Tonsil, tonsillar pillars and fossae\n Floor of mouth\n Gum (gingiva)\n Lateral walls (both) through soft palate or base of tongue\n Soft palate (inferior surface including uvula, superior [nasopharyngeal]\n surface, NOS)\nPharyngeal Tonsil (C111)\n\n
\nEpiglottis, lingual surface\n\n
\nEpiglottis, lingual surface plus both lateral walls through soft\n palate or base of tongue\nEpiglottis WITH fixation\n\n
\nOropharynx (C090-C091, C098-C099, C100, C102-C104, C108-C109)\n Paranasal Sinuses\n Soft Palate (C051, C052)\n Hard Palate\n Mandible\n Hypopharynx, NOS\n Larynx, NOS\n Posterior surface of epiglottis\n Pyriform sinus\n Soft tissue of neck\nPharyngeal Tonsil (C111)\n Hard Palate\n Mandible\n\n
\nAll Sites\nOropharynx (C090-C091, C098-C099, C100, C102-C104, C108-C109)\n Hard palate\n Mandible, NOS\nPharyngeal Tonsil (C111)\n Paranasal Sinus\nSoft Palate (C051, C052)\n Hypopharynx\n Maxilla\n Maxilla sinus (antrum)\n Nasal cavity\n Deep (extrinsic) muscle of tongue \n Palatine bone\n Tongue\nTongue Base (C019, C024)\n Hard palate\n Hypopharynx\n Larynx\n Mandible\n Genioglossus\n Geniohyoid\n Hyoglossus\n Mylohyoid\n Palatoglossus\n Styloglossus\n Ramus of mandible\n\n
\nOropharynx (C090-C091, C098-C099, C100, C102-C104, C108-C109)\n Prevertebral fascia/muscle\n\n
\nAll Sites\n Pterygoid plates\n Skull (base, bone, NOS)\nOropharynx (C090-C091, C098-C099, C100, C102-C104, C108-C109)\n Anterior 2/3 tongue\n Parotid gland\nPharyngeal Tonsil (C111)\n Brain\n Cranial nerve involvement\n Hypopharynx\n Infratemporal fossa\n Carotid artery (encasing)\n Orbit (floor, NOS)\n Soft tissues of neck\nSoft Palate (C051, C052)\n Nasopharynx (lateral, NOS)\nTongue Base (C019, C024)\n Skin\n Lateral nasopharynx\n Masseter muscle\n Masticator space \n Cranial nerve V-third division\n Muscles of mastication\n Temporalis muscles\n Parapharyngeal extension (pharyngeal space invasion)\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nLocalized, NOS\nConfined to cervix uteri or uterus, NOS, except corpus uteri, NOS\nFIGO Stage IA, IB, I [NOS]\n\n
\nBladder mucosa (for bullous edema of bladder mucosa, see code 550)\nRectal mucosa\nSigmoid colon\nSmall intestine\n \nFIGO Stage IVA\n \nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\nPrimary tumor cannot be assessed\nNot documented in medical record\nDeath Certificate Only\n\n
\nCorpus uteri, NOS\nConfined to corpus uteri, size, depth and horizontal spread unknown\n\n
\nExtension of metastasis within true pelvis\n \nFallopian tube(s)\nLigaments (broad, round, uterosacral)\nOvary(ies)\nParametrium\nVisceral peritoneum of pelvic organs\nFIGO Stage IIA\n\n
\nCul de sac (rectouterine pouch)\n \nFIGO Stage IIB\nParietal serosa of pelvic cavity\nPelvic wall(s)\nUreter, intra- and extramural\nVagina, NOS\nVaginal wall, NOS\nVulva\n \nDescribed clinically as "frozen pelvis," NOS\n\n
\nInvasion beyond uterus, NOS\nFIGO Stage II [NOS]\n\n
\nInfiltration of abdominal tissues, one of the following sites\n \nBladder wall\nBladder, NOS excluding mucosa\nHydronephrosis or nonfunctioning kidney\nPelvic wall(s)\nRectum, NOS, excluding mucosa\nRectal wall\nUrethra\n\n
\nInfiltration of abdominal tissues (code 550), more than one site\nFIGO Stage IIIB\n\n
\nAbdominal tissues involvement, NOS\nFIGO Stage III [NOS]\n\n
\nBladder wall\nBladder, NOS excluding mucosa\nRectal wall\nRectum, NOS excluding mucosa\n\n
\nNo regional lymph node involvement\n\n
\nIsolated tumor cells in regional lymph node(s) no greater than 0.2 mm\n\n
\nPara-aortic, NOS\nInternal (hypogastric, obturator, NOS)\nParacervical\nParametrial\nSacral, NOS\nLateral (laterosacral)\nMiddle (promontorial) (Gerota's node)\nPresacral\nUterosacral\nFIGO Stage IIIC\n \nAortic\nLateral aortic/lateral lumbar\nPeriaortic\nPelvic, NOS\n \nCommon\nExternal\n\n
\nRegional lymph node(s), NOS\nLymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\nRegional lymph node(s) cannot be assessed\nNot documented in medical record\nDeath Certificate Only\n\n
\nNo distant metastasis\nUnknown if distant metastasis\n\n
\nDistant lymph node(s)\nInguinal, NOS\nInguinofemoral (groin)\nNode of Cloquet or Rosenmuller (highest deep inguinal)\nSuperficial inguinal\nMediastinal\nScalene\nSupraclavicular\nDistant lymph node(s), NOS\n\n
\nDistant metastasis\n \nDistant metastasis WITH or WITHOUT distant lymph node(s)\n \nDistant metastasis, NOS\n \nFIGO Stage IVB\n \nAdnexa\nBone\nLiver\nLung\nPeritoneal spread\nUterine serosa\nCarcinomatosis\n\n
\nDeath Certificate Only\n\n
\nAny size tumor\nSuperficial tumor, NOS\nDeep tumor, NOS\nConfined to site of origin\nLocalized, NOS\n\n
\nAny size tumor\nSuperficial or deep tumor WITH involvement of\nAdjacent (connective) tissue, NOS\nAdjacent organ(s)/structure(s), NOS\nMajor vessel invasion\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\nPrimary tumor cannot be assessed\nNot documented in medical record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nRegional lymph node(s), NOS\nLymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\nRegional lymph node(s) cannot be assessed\nNot documented in medical record\nDeath Certificate Only\n\n
\nNo distant metastasis\nUnknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nBenign or borderline brain\n\n
\nAll site\n Single tumor with no invasion or seeding to other structures\nConfined to site of origin, NOS\nLocalized, NOS\n\n
\nTumor crosses the midline\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\nPrimary tumor cannot be assessed\nNot documented in medical record\nDeath Certificate Only\n\n
\nNot applicable: Information not collected for this schema\n\n
\nNo distant metastasis\nUnknown if distant metastasis\n\n
\nMicroscopic confirmation of tumor cells present in CSF by cytology\n(circulating cells in cerebral spinal fluid)\n\n
\nIntracranial spread beyond a single lesion\nTumor invades or encroaches upon ventricular system\nBrain tumors (C700, C710-C719)\n \nAnterior cranial fossa\nBrain stem\nCerebellum\nCerebrum (cerebral hemisphere)\nContralateral hemisphere\nHypothalamus\nMiddle cranial fossa\n \nPallium\nPosterior cranial fossa\nSuprasellar brain\nTapetum\nThalamus\nCNS tumors (C701, C709, C720-C729)\n \nAdjacent connective tissue\nAdjacent muscle\nBrain for cranial nerve tumor(s)\nAll sites\nSphenoid and frontal sinuses(skull)\nPineal Gland (C753)\n \nAdjacent connective/soft tissue\nCavernous sinus\nInfratentorial and central brain\n \nBone (skull) (see code 45 for other bone involvement)\nMajor blood vessel(s)\nMeninges (e.g., dura)\nMultiple/multifocal tumors\nNerves (cranial, NOS)\n\n
\n"Drop" metastasis\nGross spinal subarachnoid seeding\nVisible metastasis in cervicomedullary (junction)\n\n
\nExtra-neural metastasis\nFurther contiguous extension\nOther specified metastasis\nBrain tumors (C700, C710-C719)\n \nNasal cavity\nNasopharynx\nOther direct extension outside CNS\nPosterior pharynx\nCNS tumors (C701, C709, C720-729)\n \n \nEye\nAll Sites\n \nBlood\nBone (other than skull) (see code 25 for skull)\nBone marrow\nCarcinomatosis\nDistant lymph nodes, NOS\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nAny size tumor confined to one site WITHOUT fixation\n Laryngopharynx\n Postcricoid area\n Posterior pharyngeal wall\n Pyriform sinus\nConfined to hypopharynx\n Localized, NOS\n\n
\nAny size tumor confined to more than one subsite in code 100\n WITHOUT fixation\n\n
\nAny size tumor with extension to\n Hemilarynx WITHOUT fixation\n Oropharynx WITH or WITHOUT fixation\nAny structure listed in code 100 with fixation\n\n
\nEsophageal mucosa\n Fixation of hemilarynx or larynx\n\n
\nCentral compartment soft tissues of neck including\n Mandible\n Medial pterygoid\n Oropharynx\n Prevertebral fascia/muscle(s)\n Soft tissues of neck\n Thyroid cartilage/gland\n Prelaryngeal strap muscle(s)\n Subcutaneous fat\nCricoid cartilage\n Esophageal muscle\n Extrinsic muscle of tongue \n Fixation of oropharynx\n Hard palate\n Hemilarynx\n\n
\nHyoid bone\n\n
\nCarotid artery (encased)\n\n
\nBase of tongue\n Floor of tongue\n Mediastinal structure(s)\n Nasopharynx\nFurther contiguous extension\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nConfined to tissue or organ of origin\nLocalized, NOS\n\n
\nMore than one region of pharynx involved\n Hypopharynx\n Nasopharynx\n Oropharynx\nPharynx and oral cavity involved\nExtension to adjacent structure(s)\nFixation\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension cannot be assessed\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNone\nNo regional lymph node involvement\n\n
\nLevel I\n Middle deep cervical\nLevel IV - Lower jugular\n Jugulo-omohyoid (supraomohyoid)\n Lower deep cervical\n Virchow node\nLevel V - Posterior triangle group\n Posterior cervical\n Level VA - Spinal accessory\n Level VB - Transverse cervical, supraclavicular\nLevel VI - Anterior compartment group\n Level IA - Submental\n Laterotracheal\n Paralaryngeal\n Paratracheal - above suprasternal notch\n Perithyroidal\n Precricoid (Delphian)\n Prelaryngeal\n Pretracheal - above suprasternal notch\n Recurrent laryngeal\nLevel VII - Superior mediastinal group (for other mediastinal\n node(s), see EOD Mets)\n Level IB - Submandibular (submaxillary), sublingual\n Esophageal groove\n Paratracheal - below suprasternal notch\n Pretracheal - below suprasternal notch\nOther groups\n Cervical, NOS\n Deep cervical, NOS\n Facial \n Buccinator (buccal)\n Mandibular\n Nasolabial\nLevel II - Upper jugular\n Internal jugular, NOS\n Parapharyngeal\n Parotid \n Infraauricular\n Intraparotid\n Periparotid\n Preauricular\n Retroauricular (mastoid)\n Retropharyngeal\n Suboccipital\n Jugulodigastric (subdigastric)\n Upper deep cervical\n Level IIA - Anterior\n Level IIB - Posterior\nLevel III - Middle jugular\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNone\n No distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s))\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nLocalized, NOS\n Confined to\n Auditory bone(s) (incus, malleus, stapes)\n Vestibulocochlear organ\n Cochlea\n Semicircular ducts (ampullae, saccule, utricle)\n Septum\n Tympanic membrane (ear drum)\n\n
\nRegional extension, NOS\n Temporal bone\n Adjacent connective tissue \n Auditory tube (Eustachian tube, pharyngotympanic tube)\n Nerve(s)\n Adjacent organ(s)/structure(s) \n External auditory meatus (ear canal)\n Internal carotid artery\n Mastoid antrum\n Nasopharynx\n\n
\nMeninges\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNone\nNo regional lymph node involvement\n\n
\nLevel I\nMiddle deep cervical\nLevel IV - Lower jugular\nJugulo-omohyoid (supraomohyoid)\nLower deep cervical\nVirchow node\nLevel V - Posterior triangle group\nPosterior cervical\nLevel VA - Spinal accessory\nLevel VB - Transverse cervical, supraclavicular\nLevel VI - Anterior compartment group\nLevel IA - Submental\nLaterotracheal\nParalaryngeal\nParatracheal - above suprasternal notch\nPerithyroidal\nPrecricoid (Delphian)\nPrelaryngeal\nPretracheal - above suprasternal notch\nRecurrent laryngeal\nLevel VII - Superior mediastinal group (for other mediastinal node(s), see EOD Mets)\nEsophageal groove\nLevel IB - Submandibular (submaxillary), sublingual\nParatracheal - below suprasternal notch\nPretracheal - below suprasternal notch\nOther groups\nCervical, NOS\nDeep cervical, NOS\nFacial \nBuccinator (buccal)\nMandibular\nNasolabial\nInternal jugular, NOS\nLevel II - Upper jugular\nParapharyngeal\nParotid \nInfraauricular\nIntraparotid\nPeriparotid\nPreauricular\nRetroauricular (mastoid)\nRetropharyngeal\nSuboccipital\nJugulodigastric (subdigastric)\nUpper deep cervical\nLevel IIA - Anterior\nLevel IIB - Posterior\nLevel III - Middle jugular\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNone\n No distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s))\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nConfined to\n Mucosa of maxillary sinus (antrum)\n WITHOUT erosion or destruction of bone\nConfined to maxillary sinus, NOS\nLocalized, NOS\n\n
\nBone erosion or destruction\nHard palate\nMiddle nasal meatus\nNasal cavity\n Floor\n Lateral wall\n Septum\n Turbinates\nPalatine bone\n\n
\nBone of posterior wall of maxillary sinus\n Ethmoid sinuses (anterior, posterior, NOS)\n Floor or medial wall of orbit\n Floor or posterior wall of maxillary sinus\n Maxilla, NOS\n Pterygoid fossa\n Subcutaneous tissues\n\n
\nAnterior orbital contents\n Base of skull, NOS\n Cribriform plate\n Frontal sinus\n Infratemporal fossa\n Orbital contents including eye\n Pterygoid plates\n Skin of cheek\n Sphenoid sinus\n\n
\nBrain\n Soft palate\n Clivus\n Cranial nerves (other than V2, maxillary division of trigeminal nerve)\n Dura\n Middle cranial fossa\n Nasopharynx\n Orbital apex\n Pterygomaxillary fossa\n Temporal fossa\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nAll sites\n Nasopharynx\nEthmoid Sinus (C311)\n Brain\n Clivus\n Cranial nerves (other than V2, maxillary division of trigeminal nerve)\n Dura\n Middle cranial fossa\n Orbital apex\n\n
\nAll sites\nEthmoid Sinus (C311)\n Any structure in code 600 + hard palate\n Further contiguous extension\nNasal Cavity (C300)\n Brain\n Clivus\n Cranial nerves (other than V2, maxillary division of trigeminal nerve)\n Dura\n Middle cranial fossa\n Orbital apex\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nAll sites\n Septum\n Vestibule (edge of naris to mucocutaneous junction)\n Confined to nasal cavity, NOS\nEthmoid Sinus (C311)\n Confined to ethmoid sinus \n WITH or WITHOUT bony invasion (involvement of perpendicular plate\n of ethmoid bone or ethmoid air cells)\n Confined to ethmoid sinus, NOS\n Localized, NOS\nNasal Cavity (C300)\n Invasive tumor confined to one of the following subsites\n WITHOUT bony invasion \n Floor\n Lateral wall, including \n Meatus (superior, middle, inferior)\n Nasal conchae (superior, middle, inferior)\n\n
\nNasal Cavity (C300)\n Confined to one subsite listed in code 100 \n WITH bony invasion\n\n
\nNasal Cavity (C300)\n Confined to two or more subsites listed in code 100 \n WITHOUT bony invasion\n\n
\nNasal Cavity (C300)\n Nasal cavity WITH or WITHOUT bony invasion, one or more subsites \n Floor\n Lateral wall, including \n Meatus (superior, middle, inferior)\n Nasal conchae (superior, middle, inferior)\n Septum\n Turbinates\n Vestibule (edge of naris to mucocutaneous junction)\n Confined to two or more subsites listed in code 100 WITH bony invasion \n Choana\n Ethmoid sinus\n Nasolacrimal duct\nEthmoid Sinus (C311)\n Confined to both ethmoid sinuses \n WITH or WITHOUT bony invasion (involvement of perpendicular plate of\n ethmoid bone or ethmoid air cells)\n\n
\nAll sites\n Medial wall or floor of orbit\n Base of skull, NOS\n Cribriform plate\nNasal Cavity (C300)\n Adjacent organs/structures, NOS\n Hard palate\nEthmoid Sinus (C311)\n Orbital plate\n Maxillary sinus\n\n
\nNasal Cavity (C300)\n Maxillary sinus\n Medial wall or floor of orbit\n Orbital plate\nEthmoid Sinus (C311)\n Hard palate\n\n
\nAll sites\n Frontal sinus\n Pterygoid plates\nEthmoid Sinus (C311)\n Anterior cranial fossa (minimal extension)\n Anterior orbital contents\n Skin of cheek\n Skin of nose\n Sphenoid sinus\n\n
\nNasal Cavity (C300)\n Anterior cranial fossa (minimal extension)\n Anterior orbital contents\n Skin of cheek\n Skin of nose\n Sphenoid sinus\nEthmoid Sinus (C311)\n Any structure in code 500 + hard palate\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nInvasive tumor confined to mucosa of one of the following:\n Frontal sinus\n Sphenoid sinus\nLocalized, NOS\n\n
\nMore than one accessory sinus invaded\nCranial nerves\nHard palate\nMuscles\n Masseter\n Pterygoid\nNasal cavity\n Floor\n Lateral wall\n Nasal cavity, NOS\n Septum\nDestruction of bony wall of sinus\n Turbinates\nNasopharynx\nOrbital contents, including eye\nSoft tissue\nSkin\nBone, cartilage\n Facial bones\n Maxilla\n Orbital structure(s)\n Pterygoid fossa\n Zygoma\nBrain\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNone\nNo regional lymph node involvement\n\n
\nLevel I\n Middle deep cervical\nLevel IV - Lower jugular\n Jugulo-omohyoid (supraomohyoid)\n Lower deep cervical\n Virchow node\nLevel V - Posterior triangle group\n Posterior cervical\n Level VA - Spinal accessory\n Level VB - Transverse cervical, supraclavicular\nLevel VI - Anterior compartment group\n Level IA - Submental\n Laterotracheal\n Paralaryngeal\n Paratracheal - above suprasternal notch\n Perithyroidal\n Precricoid (Delphian)\n Prelaryngeal\n Pretracheal - above suprasternal notch\n Recurrent laryngeal\nLevel VII - Superior mediastinal group (for other mediastinal\n node(s), see EOD Mets)\n Level IB - Submandibular (submaxillary), sublingual\n Esophageal groove\n Paratracheal - below suprasternal notch\n Pretracheal - below suprasternal notch\nOther groups\n Cervical, NOS\n Deep cervical, NOS\n Facial \n Buccinator (buccal)\n Mandibular\n Nasolabial\nLevel II - Upper jugular\n Internal jugular, NOS\n Parapharyngeal\n Parotid \n Infraauricular\n Intraparotid\n Periparotid\n Preauricular\n Retroauricular (mastoid)\n Retropharyngeal\n Suboccipital\n Jugulodigastric (subdigastric)\n Upper deep cervical\n Level IIA - Anterior\n Level IIB - Posterior\nLevel III - Middle jugular\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNone\n No distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s))\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nInvolvement adjacent regions(s) of larynx\n WITH normal or impaired mobility \n Glottis\n Supraglottis\nTumor limited to larynx with vocal cord fixation\nConfined to larynx, NOS\nLocalized, NOS\n\n
\nBase of tongue\n Hypopharynx, NOS\n Paraglottic space\n Postcricoid area\n Pre-epiglottic tissues\n Pyriform sinus (pyriform fossa)\n Thyroid cartilage (inner cortex)\n Vallecula\n\n
\nCarotid artery (encased)\n Styloglossus\nMediastinal structure(s)\nOropharynx\nPrevertebral space\nSkin\nSoft tissues of neck\nStrap muscle(s)\n Omohyoid\n Sternohyoid\n Sternothyroid\nCricoid cartilage\n Thyrohyoid\nThyroid cartilage (outer cortex, NOS)\nThyroid gland\nTrachea\nFurther contiguous extension\nEsophagus\nExtrinsic muscle(s) of tongue\n Genioglossus\n Geniohyoid\n Hyoglossus\n Mylohyoid\n Palatoglossus\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n \n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL ONLY\nMetastasis in any lymph node(s) with clinically overt ENE\n\n
\nMetastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nMetastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nMetastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative\n\n
\nMetastasis in MULTIPLE ipsilateral nodes,\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nMetastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative\n\n
\nMetastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative\n\n
\nMetastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nMetastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII, see\n EOD Regional Nodes)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nInvasion through cortical bone\nMandible, NOS (upper lip)\nMaxilla, NOS (lower lip)\nUpper gingiva (from lower lip)\n\n
\nInternal carotid artery (encased)\n Masticator space\n Pterygoid plates\n Specified bone (other than mandible, maxilla)\n Skull base\nFurther contiguous extension\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nGroup 1 WITH depth of invasion (DOI) less than or equal to 5 mm\nOR unknown depth of invasion\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 5 mm and less than\nor equal to 10mm\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 10mm\n\n
\nGroup 2 WITH depth of invasion (DOI) less than or equal to 5mm\nOR unknown depth of invasion\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 5mm and less than\nor equal to 10mm\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 10mm\n\n
\nTrabecular (mandible, maxilla, NOS)\n\n
\nFloor of mouth\nInferior alveolar nerve\nNose\nSkin of face/neck\nTongue\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\nMediastinal (excluding superior mediastinal node(s), Level VII, see\n EOD Regional Nodes)\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nAnterior 2/3 of tongue\nBone\nCarotid artery (encased)\nMandible\nMediastinal structure(s)\nParotid gland\nPrevertebral space\nFurther contiguous extension\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nInvasive tumor confined to one subsite with normal vocal cord mobility\nConfined to epiglottis, NOS\nConfined to supraglottis, NOS\nLocalized, NOS\nSupraglottis\n Aryepiglottic fold\n Cartilage (arytenoid, corniculate, cuneiform, laryngeal, NOS)\n Epiglottis (infrahyoid, laryngeal [posterior] surface of epiglottis)\n Epiglottis (suprahyoid) (including tip, lingual (anterior) and\n laryngeal surfaces)\n Epilarynx, NOS\n False cords: ventricular bands/cavity/vestibular fold\n\n
\nMucosa of more than one subsite of supraglottis listed in code 100\n and/or glottis\nLimited to larynx, NOS\n\n
\nMucosa of\n Base of tongue\n Pyriform sinus (medial wall)\n Vallecula\n\n
\nTumor limited to larynx with vocal cord fixation\n\n
\nVocal cord fixation of larynx with extension to structures listed in\n code 25 OR\nInvasion of\n Cricoid cartilage\n Hypopharynx, NOS\n Paraglottic space\n Postcricoid area\n Pre-epiglottic space\n Pre-epiglottic tissues\n\n
\nThyroid cartilage (inner cortex) (minor erosion)\n\n
\nFor epiglottis (anterior surface, NOS) primaries only\nBuccal mucosa\nFloor of mouth\nGum (gingiva)\nNasopharynx\nPterygoid muscle\nSoft palate\n\n
\nEsophagus\nStrap muscle(s)\n Omohyoid\n Sternohyoid\n Sternothyroid\n Thyrohyoid\nSkin\nSoft tissues of neck\nThyroid cartilage (outer cortex, NOS)\nThyroid gland\nTrachea\nExtrinsic muscle(s) of tongue\n Genioglossus\n Geniohyoid\n Hyoglossus\n Mylohyoid\n Palatoglossus\n Styloglossus\nOropharynx, NOS\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII, see\n EOD Regional Nodes)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nCarotid artery (encased)\nMediastinal structure(s)\nPrevertebral space\nFurther contiguous extension\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nOne vocal cord with normal vocal cord mobility\n\n
\nBoth vocal cords with normal vocal cord mobility\n\n
\nInvasive tumor with normal vocal cord mobility\nIntrinsic larynx\nLaryngeal commissure(s) (anterior, posterior)\nVocal cord(s) (true cord(s), true vocal cord(s), NOS)\nConfined to glottis, NOS\nLocalized, NOS\n\n
\nImpaired vocal cord mobility\nAdjacent region(s) of larynx involved\nSubglottis\nSupraglottis\n Aryepiglottic fold\n Arytenoid cartilage \n Corniculate tubercle\n Cuneiform tubercle\n Ventricular bands (false vocal cord(s))\n\n
\nLimited to larynx WITH vocal cord fixation\nIntrinsic muscle(s) of larynx\n Aryepiglottic\n Arytenoid\n Cricoarytenoid\n Cricothyroid\n Thyroarytenoid\n Thyroepiglottic\n Vocalis\n\n
\nParaglottic space\n Thyroid cartilage (inner cortex)\n\n
\nBase of tongue\n Hypopharynx, NOS\n Postcricoid area\n Pre-epiglottic space\n Pre-epiglottic tissues\n Pyriform sinus (pyriform fossa)\n Vallecula\n\n
\nCricoid cartilage\nOropharynx, NOS\nSkin\nSoft tissues of neck\nStrap muscle(s)\n Omohyoid\n Sternohyoid\n Sternothyroid\n Thyrohyoid\nThyroid cartilage (outer cortex, NOS)\nThyroid gland\nEsophagus\nTrachea\nExtrinsic muscle(s) of tongue\n Genioglossus\n Geniohyoid\n Hyoglossus\n Mylohyoid\n Palatoglossus\n Styloglossus\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII, see\n EOD Regional Nodes)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nTumor limited to the subglottis\nInvasive tumor with normal vocal cord mobility\nLocalized, NOS\n\n
\nTumor involves adjacent regions(s) of larynx\n Glottis\n Supraglottis\nWITH normal or impaired mobility\nLimited to larynx, NOS\n\n
\nTumor limited to larynx with vocal cord fixation\nInvasion of\n Inner cortex of the thyroid cartilage\n Paraglottic space\n\n
\nBase of tongue\n Hypopharynx, NOS\n Postcricoid area\n Pre-epiglottic tissues\n Pyriform sinus (pyriform fossa)\n Vallecula\n\n
\nCricoid cartilage\nOropharynx\nSkin\nSoft tissues of neck\nStrap muscle(s)\n Omohyoid\n Sternohyoid\n Sternothyroid\n Thyrohyoid\nThyroid cartilage (outer cortex, NOS)\nThyroid gland\nEsophagus\nTrachea\nExtrinsic muscles of tongue\n Genioglossus\n Geniohyoid\n Hyoglossus\n Mylohyoid\n Palatoglossus\n Styloglossus\n\n
\nCarotid artery (encased)\nMediastinal structure(s)\nPrevertebral space\nFurther contiguous extension\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII, see\n EOD Regional Nodes)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: noninvasive, intraepithelial\n\n
\nAny size tumor or thickness\n Mucosa WITH or WITHOUT soft tissue (immediately underlying)\n Confined to site of origin, NOS\n Localized, NOS\n\n
\nDeep soft tissue involvement\n Overlying skin\n\n
\nExtension to other regional sites/structures\n Styloglossus\nWITHOUT further extension to any sites/structures considered very\n advanced disease (see code 600)\nBone\nCartilage\nDeep extrinsic muscle of tongue\n Genioglossus\n Hyoglossus\n Palatoglossus\n\n
\nBrain\nFurther contiguous extension\nCarotid artery\nDura\nLower cranial nerves (IX, X, XI, XII)\nMasticator space\nMediastinal structures\nPrevertebral space\nSkull base\nVery advanced disease, NOS\n\n
\nModerately advanced disease, NOS\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nLevel I\n Middle deep cervical\nLevel IV - Lower jugular\n Jugulo-omohyoid (supraomohyoid)\n Lower deep cervical\n Virchow node\nLevel V - Posterior triangle group\n Posterior cervical\n Level VA - Spinal accessory\n Level VB - Transverse cervical, supraclavicular\nLevel VI - Anterior compartment group\n Level IA - Submental\n Laterotracheal\n Paralaryngeal\n Paratracheal - above suprasternal notch\n Perithyroidal\n Precricoid (Delphian)\n Prelaryngeal\n Pretracheal - above suprasternal notch\n Recurrent laryngeal\nLevel VII - Superior mediastinal group (for other mediastinal\n node(s), see EOD Mets)\n Level IB - Submandibular (submaxillary), sublingual\n Esophageal groove\n Paratracheal - below suprasternal notch\n Pretracheal - below suprasternal notch\nOther groups\n Cervical, NOS\n Deep cervical, NOS\n Facial \n Buccinator (buccal)\n Mandibular\n Nasolabial\nLevel II - Upper jugular\n Internal jugular, NOS\n Parapharyngeal\n Parotid \n Infraauricular\n Intraparotid\n Periparotid\n Preauricular\n Retroauricular (mastoid)\n Retropharyngeal\n Suboccipita\n Jugulodigastric (subdigastric)\n Upper deep cervical\n Level IIA - Anterior\n Level IIB - Posterior\nLevel III - Middle jugular\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII,\n see EOD Regional Nodes)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nCarcinoma in situ\n\n
\nLesion(s) confined to dermis\n Subcutaneous tissue (through entire dermis)\n\n
\nBone erosion (minor or NOS)\n Deep invasion\nSkeletal muscle\nUnderlying cartilage\nPerineural invasion\n\n
\nMaxilla\n Mandible\n Orbital bone\n Temporal bone\n\n
\nGross cortical bone/marrow\n\n
\nSkull base invasion\n Skull base foramen\n\n
\nFurther contiguous extension\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\nMediastinal (excluding superior mediastinal node(s), Level VII)\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, non-invasive, high-grade dysplasia\n (Adeno)carcinoma, noninvasive, in a polyp\n\n
\nAll subsites\n Trachea\nIntrathoracic, upper or mid-portion, esophagus\n Blood vessel(s), major \n Pulmonary artery/vein\n Vena cava\n Carina\n Trachea\nIntrathoracic, lower portion (abdominal), esophagus\n Blood vessel(s) \n Vena cava\n Adjacent structure(s), NOS\nIntrathoracic esophagus (all portions)\n Adjacent rib(s)\n Lung via bronchus\n Mediastinal structure(s), NOS\n Thoracic vertebra(e)\nEsophagus GE Junction\n Liver\n Pancreas\n Small intestine (duodenum [via serosa], ileum, jejunum)\n Spleen\n Aorta\n Transverse colon (including flexures)\nCervical esophagus\n Blood vessel(s) \n Carotid artery\n Subclavian artery\n Carina\n Cervical vertebra(e)\n\n
\nAll subsites\nFurther contiguous extension\n Airway\n Vertebral body\nCervical/upper esophagus\n Lung\n Mainstem bronchus\nEsophagus GE Junction\n Trachea\nStated as unresectable, NOS\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nIntramucosal, NOS\n Lamina propria\n Mucosa, NOS\n Muscularis mucosae\n\n
\nSubmucosa (superficial invasion)\n\n
\nConfined to esophagus, NOS\nLocalized, NOS\n\n
\nMuscularis propria\n\n
\nExtension through wall, NOS\n Invasion through muscularis propria or muscularis, NOS\n Perimuscular tissue invaded\n Subserosal tissue/(sub)serosal fat invaded\n\n
\nAdventitia and/or soft tissue invaded\n Omentum (greater, lesser, NOS)\nPerigastric fat\nEsophagus is described as "FIXED"\nExtension to adjacent (connective) tissue\nWITHOUT perforation of visceral peritoneum covering these structures\nGastric artery\nLigaments\n Gastrocolic\n Gastrohepatic\n Gastrosplenic\n\n
\nAll subsites\n Visceral peritoneum (including perforation)\nCervical esophagus\n Hypopharynx\n Jugular vein\n Larynx\n Thyroid gland\nIntrathoracic esophagus, lower portion (abdominal)\n Blood vessel(s), major \n Gastric artery/vein\n Stomach, cardia (via serosa)\n Azygos vein\n Diaphragm (excluding abdominal/lower esophagus, see code 500)\n Mesothelium\n Pericardium (excluding thoracic/middle esophagus, see code 500)\n Peritoneum, NOS\n Pleura (excluding cervical/upper esophagus, see code 500)\n Serosa (invasion of/or through)\n Tunica serosa\n\n
\nAbdominal/lower esophagus\n Kidney\n Retroperitoneum\n Diaphragm fixed\nCervical/upper esophagus\n Pleura\nThoracic/middle esophagus\n Pericardium\nEsophagus GE Junction\n Abdominal wall\n Adrenal (suprarenal) gland\n\n
\nNo regional lymph node involvement\n\n
\nFor all subsites (excluding GE junction)\n Scalene (inferior deep cervical) (1)\n Supraclavicular (transverse cervical) (1)\n Intrathoracic esophagus, upper or middle, only\n Internal jugular, NOS \n Deep cervical, NOS \n Lower, NOS \n Jugulo-omohyoid (supraomohyoid)\n Middle\n Upper cervical, NOS \n Jugulodigastric (subdigastric)\n Peri-/paraesophageal (8L, 8M)\n Intrabronchial \n Carinal (tracheobronchial) (10R, 10L) (tracheal bifurcation)\n Hilar (bronchopulmonary) (proximal lobar) (pulmonary root)\n Peritracheal\n Left gastric (superior gastric) (17) \n Cardiac (cardial)\n Lesser curvature\n Perigastric, NOS\n Posterior mediastinal (tracheoesophageal)\n Superior mediastinal\nCervical esophagus only\nIntrathoracic esophagus, lower (abdominal) only\n Left gastric (superior gastric) (17) \n Cardiac (cardial)\n Lesser curvature\n Perigastric, NOS\n Posterior mediastinal (3P) (tracheoesophageal)\nEsophagus GE Junction\n Celiac (20) \n Hepatic (excluding hepatoduodenal)\n Left gastric (superior gastric), NOS \n Cervical, NOS \n Cardiac\n Cardioesophageal\n Gastric, left (17)\n Gastropancreatic, left\n Lesser curvature\n Lesser omental\n Pericardial (16)\n Pancreaticosplenic (pancreaticolineal)\n Pancreatoduodenal\n Perigastric, NOS\n Anterior deep cervical (laterotracheal) (recurrent laryngeal)\n Peripancreatic\n Right gastric (inferior gastric), NOS \n Gastrocolic\n Gastroduodenal\n Gastroepiploic (gastro-omental), right or NOS\n Gastrohepatic\n Greater curvature\n Greater omental\n Pyloric, NOS \n Infrapyloric (subpyloric)\n Deep cervical, NOS \n Suprapyloric\n Splenic (lineal), NOS \n Gastroepiploic (gastro-omental), left\n Splenic hilar\nNodule(s) in perigastric fat\n Upper, NOS \n Jugulodigastric (subdigastric)\n Internal jugular, NOS\n\n
\nAll subsites\n Subaortic\n Paratracheal (2R, 2L, 4R, 4L)\n Posterior mediastinal (3P)\n Superior mediastinal\nIntrathoracic esophagus, upper or middle, only\n Aortopulmonary (5) \n Para-aortic (ascending aorta or phrenic)\n Cervical\nLower thoracic (abdominal) esophagus\n Aortopulmonary (5) \n Anterior mediastinal (6)\n Para-aortic (ascending aorta or phrenic)\n Subaortic\n Celiac (20)\n Paratracheal (2R, 2L, 4R, 4L)\n Superior mediastinal\nEsophagus GE Junction\n Paraesophageal, NOS\n Periesophageal, NOS \n Aortopulmonary (5)\n Paraesophageal, lower (8l)\n Diaphragmatic (15)\n Paraesophageal, middle (8m)\n Paratracheal, lower (4L, 4R)\n Paratracheal, upper (2L, 2R)\n Posterior mediastinal (3p)\n Supraclavicular (1)\n Tracheobronchial (hilar) (10L, 10R)\n Mediastinal, NOS\n Pulmonary ligament (9)\n Subcarinal (tracheal carina) (7)\n Cervical esophagus\n Aortopulmonary (5) \n Para-aortic (ascending aorta or phrenic)\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n\n
\nDistant lymph node(s)\n Porta hepatis (portal) (hilar) (in hilus of liver)\n Retropancreatic\n Retroperitoneal\nDistant lymph node(s), NOS\n Common hepatic (18)\n Splenic (19)\nEsophagus GE Junction\n Hepatoduodenal\n Mesenteric, NOS \n Inferior mesenteric\n Superior mesenteric\n Para-aortic\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, non-invasive, high-grade dysplasia\n (Adeno)carcinoma, noninvasive, in a polyp\n\n
\nAll subsites\n Trachea\nIntrathoracic, upper or mid-portion, esophagus\n Blood vessel(s), major \n Pulmonary artery/vein\n Vena cava\n Carina\n Trachea\nIntrathoracic, lower portion (abdominal), esophagus\n Blood vessel(s) \n Vena cava\n Adjacent structure(s), NOS\nIntrathoracic esophagus (all portions)\n Adjacent rib(s)\n Lung via bronchus\n Mediastinal structure(s), NOS\n Thoracic vertebra(e)\nEsophagus GE Junction\n Liver\n Pancreas\n Small intestine (duodenum [via serosa], ileum, jejunum)\n Spleen\n Aorta\n Transverse colon (including flexures)\nCervical esophagus\n Blood vessel(s) \n Carotid artery\n Subclavian artery\n Carina\n Cervical vertebra(e)\n\n
\nAll subsites\nFurther contiguous extension\n Airway\n Vertebral body\nCervical/upper esophagus\n Lung\n Mainstem bronchus\nEsophagus GE Junction\n Trachea\nStated as unresectable, NOS\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nIntramucosal, NOS\n Lamina propria\n Mucosa, NOS\n Muscularis mucosae\n\n
\nSubmucosa (superficial invasion)\n\n
\nConfined to esophagus, NOS\nLocalized, NOS\n\n
\nMuscularis propria\n\n
\nExtension through wall, NOS\n Invasion through muscularis propria or muscularis, NOS\n Perimuscular tissue invaded\n Subserosal tissue/(sub)serosal fat invaded\n\n
\nAdventitia and/or soft tissue invaded\n Omentum (greater, lesser, NOS)\nPerigastric fat\nEsophagus is described as "FIXED"\nExtension to adjacent (connective) tissue\nWITHOUT perforation of visceral peritoneum covering these structures\nGastric artery\nLigaments\n Gastrocolic\n Gastrohepatic\n Gastrosplenic\n\n
\nAll subsites\n Visceral peritoneum (including perforation)\nCervical esophagus\n Hypopharynx\n Jugular vein\n Larynx\n Thyroid gland\nIntrathoracic esophagus, lower portion (abdominal)\n Blood vessel(s), major \n Gastric artery/vein\n Stomach, cardia (via serosa)\n Azygos vein\n Diaphragm (excluding abdominal/lower esophagus, see code 500)\n Mesothelium\n Pericardium (excluding thoracic/middle esophagus, see code 500)\n Peritoneum, NOS\n Pleura (excluding cervical/upper esophagus, see code 500)\n Serosa (invasion of/or through)\n Tunica serosa\n\n
\nAbdominal/lower esophagus\n Kidney\n Retroperitoneum\n Diaphragm fixed\nCervical/upper esophagus\n Pleura\nThoracic/middle esophagus\n Pericardium\nEsophagus GE Junction\n Abdominal wall\n Adrenal (suprarenal) gland\n\n
\nNo regional lymph node involvement\n\n
\nFor all subsites (excluding GE junction)\n Scalene (inferior deep cervical) (1)\n Supraclavicular (transverse cervical) (1)\n Intrathoracic esophagus, upper or middle, only\n Internal jugular, NOS \n Deep cervical, NOS \n Lower, NOS \n Jugulo-omohyoid (supraomohyoid)\n Middle\n Upper cervical, NOS \n Jugulodigastric (subdigastric)\n Peri-/paraesophageal (8L, 8M)\n Intrabronchial \n Carinal (tracheobronchial) (10R, 10L) (tracheal bifurcation)\n Hilar (bronchopulmonary) (proximal lobar) (pulmonary root)\n Peritracheal\n Left gastric (superior gastric) (17) \n Cardiac (cardial)\n Lesser curvature\n Perigastric, NOS\n Posterior mediastinal (tracheoesophageal)\n Superior mediastinal\nCervical esophagus only\nIntrathoracic esophagus, lower (abdominal) only\n Left gastric (superior gastric) (17) \n Cardiac (cardial)\n Lesser curvature\n Perigastric, NOS\n Posterior mediastinal (3P) (tracheoesophageal)\nEsophagus GE Junction\n Celiac (20) \n Hepatic (excluding hepatoduodenal)\n Left gastric (superior gastric), NOS \n Cervical, NOS \n Cardiac\n Cardioesophageal\n Gastric, left (17)\n Gastropancreatic, left\n Lesser curvature\n Lesser omental\n Pericardial (16)\n Pancreaticosplenic (pancreaticolineal)\n Pancreatoduodenal\n Perigastric, NOS\n Anterior deep cervical (laterotracheal) (recurrent laryngeal)\n Peripancreatic\n Right gastric (inferior gastric), NOS \n Gastrocolic\n Gastroduodenal\n Gastroepiploic (gastro-omental), right or NOS\n Gastrohepatic\n Greater curvature\n Greater omental\n Pyloric, NOS \n Infrapyloric (subpyloric)\n Deep cervical, NOS \n Suprapyloric\n Splenic (lineal), NOS \n Gastroepiploic (gastro-omental), left\n Splenic hilar\nNodule(s) in perigastric fat\n Upper, NOS \n Jugulodigastric (subdigastric)\n Internal jugular, NOS\n\n
\nAll subsites\n Subaortic\n Paratracheal (2R, 2L, 4R, 4L)\n Posterior mediastinal (3P)\n Superior mediastinal\nIntrathoracic esophagus, upper or middle, only\n Aortopulmonary (5) \n Para-aortic (ascending aorta or phrenic)\n Cervical\nLower thoracic (abdominal) esophagus\n Aortopulmonary (5) \n Anterior mediastinal (6)\n Para-aortic (ascending aorta or phrenic)\n Subaortic\n Celiac (20)\n Paratracheal (2R, 2L, 4R, 4L)\n Superior mediastinal\nEsophagus GE Junction\n Paraesophageal, NOS\n Periesophageal, NOS \n Aortopulmonary (5)\n Paraesophageal, lower (8l)\n Diaphragmatic (15)\n Paraesophageal, middle (8m)\n Paratracheal, lower (4L, 4R)\n Paratracheal, upper (2L, 2R)\n Posterior mediastinal (3p)\n Supraclavicular (1)\n Tracheobronchial (hilar) (10L, 10R)\n Mediastinal, NOS\n Pulmonary ligament (9)\n Subcarinal (tracheal carina) (7)\n Cervical esophagus\n Aortopulmonary (5) \n Para-aortic (ascending aorta or phrenic)\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n\n
\nDistant lymph node(s)\n Porta hepatis (portal) (hilar) (in hilus of liver)\n Retropancreatic\n Retroperitoneal\nDistant lymph node(s), NOS\n Common hepatic (18)\n Splenic (19)\nEsophagus GE Junction\n Hepatoduodenal\n Mesenteric, NOS \n Inferior mesenteric\n Superior mesenteric\n Para-aortic\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n (Adeno)carcinoma, noninvasive, in a polyp\n\n
\nAbdominal wall\n Adrenal (suprarenal) gland\n Aorta\n Celiac axis\n Kidney\n Retroperitoneum\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nIntramucosal, NOS\nLamina propria\nMuscularis mucosae\nPerimuscular tissue invaded\nMucosa\n WITH or WITHOUT intraluminal extension to esophagus or duodenum\n\n
\nSubmucosa (superficial, NOS)\n WITH or WITHOUT intraluminal extension to esophagus or duodenum\n\n
\nConfined to polyp (head, stalk, NOS)\nImplants inside stomach\nConfined to stomach, NOS\nLocalized, NOS\n\n
\nMuscularis propria (but not through)\n WITH or WITHOUT intraluminal extension to esophagus or duodenum\nLinitis plastica and no other information regarding extension available\n\n
\nThrough muscularis propria or muscularis, NOS\n WITH or WITHOUT intraluminal extension to esophagus or duodenum\nExtension through wall, NOS\nPerimuscular tissue invaded\nSubserosal tissue/(sub)serosal fat invaded\n\n
\nExtension to adjacent (connective) tissue\n WITHOUT perforation of visceral peritoneum covering these structures\nGastric artery\nLigaments\n Gastrocolic\n Gastrohepatic\n Gastrosplenic\nOmentum (greater, lesser, NOS)\nPerigastric fat\n\n
\nMesothelium\n Serosa\n Tunica serosa\n Visceral peritoneum\n\n
\nColon/mesocolon (including transverse and flexures)\n Spleen\n Diaphragm\n Duodenum (via serosa)\n Esophagus (via serosa)\n Ileum\n Jejunum\n Liver\n Pancreas\n Small intestine, NOS\n\n
\nNo regional lymph node involvement\n\n
\nCeliac artery\n Gastropancreatic, left\n Lesser curvature\n Lesser omentum\n Paracardial\nPancreaticosplenic (pancreaticolineal)\nPerigastric, NOS\nPeripancreatic\nPyloric, NOS\n Infrapyloric (subpyloric)\n Suprapyloric\nCommon hepatic artery\nRight gastric (inferior gastric, NOS)\n Gastrocolic\n Gastroduodenal\n Gastroepiploic (gastro-omental), right or NOS\n Gastrohepatic\n Greater curvature\n Greater omentum\n Pancreaticoduodenal\nSplenic (lineal), NOS\n Gastroepiploic (gastro-omental), left\nHepatic, NOS\n Splenic hilar/hilum\nNodule(s) in perigastric fat\nLeft gastric (superior gastric), NOS\n Cardial, NOS\n Cardioesophageal\n Gastric artery\n Gastric, left\n Gastrohepatic\n\n
\nLesser curvature (C165)\n Hepatoduodenal\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), including\n Retroperitoneal\n Distant lymph node(s), NOS\n Hepatoduodenal (all subsites EXCEPT lesser curvature)\n Intra-abdominal\n Mesenteric (inferior, superior, NOS)\n Middle colic\n Pancreaticoduodenal (all subsites EXCEPT greater curvature)\n Para-aortic\n Porta hepatic (portal) (hilar) (in hilus of liver)\n Retropancreatic\n\n
\nCarcinomatosis\nKrukenberg tumor (metastasis to ovary(ies))\nMalignant (positive) peritoneal cytology\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n (Adeno)carcinoma, noninvasive, in a polyp or adenoma\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nIntramucosa, NOS\n Lamina propria\n Mucosa, NOS\n Muscularis mucosae\n\n
\nSubmucosa (superficial invasion)\n\n
\nConfined to polyp (head, stalk, NOS)\n Intraluminal spread to other segments of small intestine or cecum\nConfined to small intestine, NOS\n Localized, NOS\n\n
\nMuscularis propria\n\n
\nExtension through wall, NOS\n Subserosal tissue/(sub)serosal fat invaded\n Through muscularis propria or muscularis, NOS\n Transmural, NOS\n Wall, NOS\n\n
\nAdjacent (connective) tissue(s), NOS (without serosal penetration)\n Fat, NOS\n Mesenteric fat\n Mesentery (adjacent loops of bowel)\n Nonperitonealized perimuscular tissue\n Retroperitoneum\n\n
\nAbdominal wall (via serosa)\n Ampulla of Vater\n Blood vessel(s), major \n Aorta\n Gastroduodenal artery\n Portal vein\n Renal vein\n Superior mesenteric artery or vein\n Vena cava\n Diaphragm\n Extrahepatic bile duct(s)\nAdjacent organ(s)/structure(s)\n Gallbladder\n Hepatic flexure\n Kidney (right or NOS)\n Liver (quadrate lobe, right lobe or NOS)\n Omentum\n Pancreas (pancreatic duct)\n Stomach\n Transverse colon\n Ureter, right\nJejunum and Ileum (C171, C172)\nMesothelium\n Colon including appendix\nOther loops of small intestine\nOther segments of small intestine (via serosa)\nSerosa\nTunica serosa\nVisceral peritoneum\nDuodenum (C170)\n\n
\nJejunum and Ileum (C171, C172)\n Bladder\n Fallopian tube(s)\n Ovary(ies)\n Uterus\nFurther contiguous extension\n\n
\nNo regional lymph node involvement\n\n
\nDuodenum (C170)\nJejunum and ileum (C171, C172)\n Cecal (anterior, posterior, retrocecal) (terminal ileum only)\n Ileocecal (ileocolic) (terminal ileum only)\n Mesenteric, NOS\n Superior mesenteric\n Duodenal\n Gastroduodenal\n Hepatic\n Pancreaticoduodenal (inferior)\n Pericholodochal (common bile duct)\n Pyloric (infrapyloric, subpyloric, NOS)\n Retropancreatic\n Superior mesenteric\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Celiac\n Pericholedochal (jejunum and ileum only)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n (Adeno) carcinoma, noninvasive, in a polyp or adenoma\n\n
\nAbdominal wall\n Adherent to other organs or structures\n Greater omentum\n Retroperitoneum (excluding fat)\n Small intestine\nTumor found in adhesion(s) if microscopic examination performed\n\n
\nAdrenal (suprarenal) gland\n Ovary\n Ureter\n Uretus\nFurther contiguous extension\n Bladder\n Diaphragm\n Fallopian tube\n Fistula to skin\n Gallbladder\n Kidney\n Liver\n Other segment(s) of colon/rectum via serosa\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nLow-grade appendiceal mucinous neoplasm confined by the \n muscularis propria (LAMN)\nAcellular mucin or mucinous epithelium may invade into muscularis\n propria\n\n
\nLamina propria\n Mucosa (intramucosal, NOS)\n Muscularis mucosae\n\n
\nSubmucosa\nConfined to appendix, NOS\n Confined to polyp, NOS\n Localized, NOS\n\n
\nMuscularis propria\n\n
\nExtension through wall, NOS\n Invasion through muscularis propria\n Non-peritonealized pericolic tissues invaded\n Perimuscular tissue invaded\n Subserosa\n Transmural, NOS\n Wall, NOS\n\n
\nAdjacent tissue(s), NOS\n Connective tissue\n Fat, NOS\n Mesenteric fat\n Mesentery\n Mesoappendix\n Pericolic fat\n\n
\nInvasion of/through serosa (mesothelium) (visceral peritoneum)\n\n
\nFor mucinous tumor only\nPeritoneal involvement confined within right lower quadrant WITH\n or WITHOUT further local extension\n\n
\nNo regional lymph node involvement\n\n
\nCecal\n Paracolic/pericolic\n Anterior (prececal) \n Posterior (retrocecal)\n Right colic\nColic, NOS\n Epicolic (adjacent to bowel wall)\n Ileocolic\n Mesenteric, NOS\n Mesocolic, NOS\n\n
\nTumor deposit(s) in subserosa or mesentery\n No regional lymph node metastasis\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nIntraperitoneal acellular mucin\nWITHOUT peritoneal mucinous deposits containing tumor cells or UNKNOWN\n\n
\nIntraperitoneal metastasis\nWITH or WITHOUT peritoneal mucinous deposits containing tumor cells \n\n
\nDistant lymph node(s)\nInferior mesenteric\nSuperior mesenteric\nDistant lymph node(s), NOS\n\n
\nNon-peritoneal metastasis\nWITH or WITHOUT distant lymph nodes or intraperitoneal spread\nIntraperitoneal spread WITH distant lymph nodes\nOther specified distant metastasis\nCarcinomatosis\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nInternal carotid artery (encased)\n Masticator space\n Pterygoid plates\n Skull base\n Specified bone (other than mandible, maxilla)\nFurther contiguous extension\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nGroup 1 WITH depth of invasion (DOI) less than or equal to 5 mm\n OR unknown depth of invasion\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than5 mm and less than \nor equal to 10mm\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 10 mm\n\n
\nGroup 2 WITH depth of invasion (DOI) less than or equal to 5 mm\n OR unknown depth of invasion\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 5 mm and less than\nor equal to 10mm\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 10 mm\n\n
\nLateral pharyngeal wall\n Soft palate, inferior surface\n Tonsillar pillars and fossae\n Tonsils\n\n
\nInvasion through cortical bone (mandible, maxilla, NOS)\n Trabecular bone (mandible, maxilla, NOS)\n Skin of face\nDeep (extrinsic) muscles of tongue\nGenioglossus\nGeniohyoid\nHyoglossus\nMylohyoid\nPalatoglossus\nStyloglossus\nMaxillary sinus (antrum)\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\nMediastinal (excluding superior mediastinal node(s), Level VII, see\n EOD Regional Ndoes)\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n (Adeno)carcinoma in a polyp or adenoma, noninvasive\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nIntramucosal, NOS\n Lamina propria\n Mucosa, NOS\nConfined to, but not through muscularis mucosa\n\n
\nSubmucosa (superficial invasion)\n Rectum: WITH or WITHOUT intraluminal extension to colon and/or\n anal canal/anus\nThrough the muscularis mucosa but not into the muscularis propria\nConfined to polyp (head, stalk, NOS)\n Confined to colon, rectum, rectosigmoid, NOS\n Localized, NOS\n\n
\nMuscularis propria invaded\nRectum: WITH or WITHOUT intraluminal extension to colon and/or\n anal canal/anus\n\n
\nExtension through wall, NOS\n Wall, NOS\n Invasion through muscularis propria or muscularis, NOS\nRectum: WITH or WITHOUT intraluminal extension to colon and/or\n anal canal/anus\nNon-peritonealized pericolic/perirectal tissues invaded\nPericolic/perirectal tissues invaded, NOS (unknown whether non-peritonealized or peritonealized\n Perimuscular tissue invaded\n Subserosal tissue/(sub)serosal fat invaded\n Transmural, NOS\n\n
\nAdjacent (connective) tissue(s), NOS\n Retroperitoneal fat (ascending and descending colon only)\n Fat, NOS\n Gastrocolic ligament (transverse colon and flexures)\n Greater omentum (transverse colon and flexures)\n Mesentery (including mesenteric fat, mesocolon)\n Pericolic fat\n Perirectal fat\n Peritonealized pericolic/perirectal tissues invaded\n Rectovaginal septum (rectum)\n\n
\nMesothelium\n Serosa\n Tunica serosa\nInvasion of/through the visceral peritoneum\n\n
\nAdherent to other organs or structures clinically with no microscopic examination\nGreater omentum\nKidney, right\nLiver, right lobe\nUreter, right\nTransverse colon and flexures (C183, C184, C185)\nBile ducts\nGallbladder\nKidney\nLiver\nPancreas\nTumor found in adhesion(s) if microscopic examination performed\nSpleen\nStomach\nDescending colon (C186)\nGreater omentum\nKidney, left\nPelvic wall\nSpleen\nUreter, left\nSigmoid colon (C187)\nGreater omentum\nAll Colon subsites\nPelvic wall\nRectosigmoid (C199)\nCul de sac (rectouterine pouch)\nPelvic wall/pelvic plexuses\nSmall intestine\nRectum (C209)\nAnus/anal canal\nBladder (males only)\nCul de sac (rectouterine pouch)\nDuctus deferens\nAbdominal wall\nPelvic wall\nProstate\nRectovaginal septum\nRectovesical fascia (males only)\nSeminal vesicle(s)\nSkeletal muscles of pelvic floor\nVagina\nRetroperitoneum (excluding fat)\nSmall intestine\nCecum (C180)\nGreater omentum\nAscending colon (C182)\n\n
\nAll Colon subsites\nUterus\nCecum (C180)\nKidney\nLiver\nUreter\nTransverse colon and flexures\nUreter\nSigmoid colon\nCul de sac (rectouterine pouch)\nUreter\nAdrenal (suprarenal) gland\nRectosigmoid\nBladder\nColon via serosa\nFallopian tube(s)\nOvary(ies)\nProstate\nSkeletal muscles of pelvic floor\nUreter(s)\nVagina\nRectum\nBladder\nBladder (females only)\nBone(s) of pelvis\nCervix\nPerineum, perianal skin\nSacrum\nSacral plexus\nUrethra\nFurther contiguous extension\nDiaphragm\nFallopian tube\nFistula to skin\nGallbladder\nOther segment(s) of colon via serosa\nOvary(ies)\n\n
\nNo regional lymph node involvement and no tumor deposits (TD)\n\n
\nTumor deposits (TD) in the subserosa, mesentery, mesorectal\n or nonperitonealized pericolic or perirectal tissues\n WITHOUT regional nodal metastasis\n\n
\nAll colon subsites\nAnterior cecal (prececal)\nPosterior cecal (retrocecal)\nColic (right)\nIleocolic\nPeriappendiceal\nAscending colon (C182)\nColic (middle-right branch, right)\nIleocolic\nHepatic flexure (C183)\nColic (middle, right)\nColic, NOS\nIleocolic\nTransverse colon (C184)\nColic (middle)\nSplenic flexure (C185)\nColic (left, middle)\nMesenteric (inferior)\nDescending colon (C186)\nColic (left)\nMesenteric (inferior)\nSigmoid\nEpicolic (adjacent to bowel wall)\nSigmoid colon (C187)\nColic (left)\nMesenteric (inferior)\nRectal (superior) (hemorrhoidal)\nRectosigmoid\nSigmoid (sigmoidal) (sigmoid mesenteric)\nSuperior rectal (hemorrhoidal)\nRectosigmoid (C199)\nHemorrhoidal (middle, superior)\nMesenteric (inferior)\nMesenteric, NOS\nMesorectal\nPericolic\nPerirectal\nRectal (middle, superior)\nSigmoid (mesenteric)\nRectum (C209)\nHemorrhoidal (middle, superior)\nIliac (hypogastric, internal, obturator) (see EOD Mets for common, external, NOS)\nMesenteric (inferior)\nMesorectal\nMesocolic, NOS\nPerirectal\nRectal (inferior)\nSacral, NOS \nLateral sacral (laterosacral)\nMiddle sacral (promontorial) (Gerota's node)\nPresacral\nSigmoidal (sigmoid mesenteric)\nParacolic\nPericolic\nCecum (C180)\nCecal, NOS \n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nSINGLE distant lymph node chain\n\n
\nSINGLE distant organ (except peritoneum)\n\n
\nMetastasis to MULTIPLE distant lymph node chains\n WITH or WITHOUT single distant organ (except peritoneum)\n\n
\nMULTIPLE distant organs (excluding peritoneum)\n WITH or WITHOUT distant lymph node(s)\n\n
\nPeritoneal surface metastasis (peritoneum)\n WITH or WITHOUT distant lymph node(s) or distant organ(s)\nCarcinomatosis\n\n
\nDistant lymph node(s), NOS\nNot specified as single or multiple chains\nDistant metastasis, NOS\nNot specified as single or multiple organs, or peritoneum\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n Anal intraepithelial neoplasia III\n Bowen disease\n\n
\nAny size tumor with invasion to\n Localized, NOS\n Intramucosa\n Lamina propria\n Mucosa, NOS\n Muscularis mucosae\n Muscularis propria (internal sphincter)\n Submucosa (superficial invasion)\nIncidental finding of malignancy in hemorrhoid, NOS\nConfined to anus, NOS\n\n
\nAny size tumor with extension to\n Subcutaneous perianal tissue\n Ischiorectal fat/tissue\n Perianal skin\n Perirectal skin\n Rectal mucosa or submucosa\n Rectal wall\n Skeletal muscle(s) \n Anal sphincter (external)\n Levator ani\n\n
\nPerineum\nVulva\n\n
\nBladder\n Broad ligament(s)\n Cervix uteri\n Corpus uteri\n Pelvic peritoneum\n Prostate\n Urethra\n Vagina\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nAnorectal\n Inferior hemorrhoidal\n Inguinal (femoral) (deep, superficial)\n Internal iliac (hypogastric)\n Lateral sacral (laterosacral)\n Mesorectal\n Obturator\n Perirectal\n Superior rectal (hemorrhoidal) (femoral)\n\n
\nExternal iliac node(s) WITHOUT any nodes in code 300\n\n
\nExternal iliac node(s) WITH any nodes in code 300\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIntraepithelial, noninvasive\n\n
\nNo evidence of primary tumor\n\n
\nUnknown, extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nAny size tumor\n Single lesion (one lobe)\n WITHOUT or UNKNOWN vascular invasion\nConfined to liver, NOS\n Localized, NOS\n\n
\nCode 100 WITH vascular invasion\n\n
\nMultiple (satellite) nodules/tumors confined to one lobe\n WITH or WITHOUT vascular invasion\n\n
\nAny size tumor\n More than one lobe involved by contiguous growth (single lesion) \n WITHOUT or UNKNOWN vascular invasion\n\n
\nCode 300 WITH vascular invasion\n\n
\nMultiple (satellite) nodules/tumors in more than one lobe of liver\n or on surface of parenchyma\n WITH or WITHOUT vascular invasion\n\n
\nDiaphragm\nCoronary\nFalciform\nHepatoduodenal\nHepatogastric\nRound (of liver)\nTriangular\nPeritoneum, NOS\nParietal\nVisceral\nMajor vascular invasion, NOS\n Extrahepatic bile duct(s)\n Extrahepatic blood vessel(s)\nHepatic artery\nPortal vein\nVena cava\nGallbladder\n Lesser omentum\n Ligament(s)\n\n
\nPancreas\n Pleura\n Stomach\nFurther contiguous extension\n\n
\nNo regional lymph node involvement\n\n
\nCaval\nHepatic, NOS\nHepatic artery\nHepatic pedicle\nInferior vena cava\nPorta hepatis (portal) (hilar) [in hilus of liver]\nHepatoduodenal ligament\n Periportal\n Portal vein\n\n
\nInferior phrenic nodes\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\nRenal artery\nRetroperitoneal, NOS\nDistant lymph node(s), NOS\nAortic (para-aortic, periaortic)\nCardiac\nCoronary artery\nDiaphragmatic, NOS\nLateral (aortic) (lumbar)\nPericardial (pericardiac)\nPeripancreatic (near head of pancreas only)\nPosterior mediastinal (tracheoesophageal) including juxtaphrenic nodes\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n Intraductal tumor\n Biliary intraepithelial neoplasia grade 3 (BiIIN-3)\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nAny size tumor\nSolitary tumor\n WITHOUT or UNKNOWN intrahepatic vascular invasion\nConfined to intrahepatic bile duct, NOS\n Localized, NOS\n\n
\nCode 100 WITH intrahepatic vascular invasion\n\n
\nMultiple tumors\n WITH or WITHOUT intrahepatic vascular invasion\n\n
\nInvasion into, but not through the visceral peritoneum\n\n
\nInvasion beyond visceral peritoneum into adjacent connective tissues\nWITHOUT invasion of extrahepatic structures/organs\n\n
\nExtrahepatic bile ducts PLUS satellite nodules in more than one lobe\n Vena cava\nHepatic artery (proper)\nGallbladder\nLesser omentum\nLigament(s)\n Coronary\n Falciform\n Hepatoduodenal\n Hepatogastric\n Round (of liver)\nOR multiple tumors with extrahepatic major vascular invasion\n Triangular\nPeritoneum (parietal, NOS)\nRetrohepatic vena cava\nAbdominal wall\nColon\nCommon bile duct\nDiaphragm\nDuodenum\nExtrahepatic structures, NOS\n Retrohepatic vena cava\n\n
\nMultiple (satellite) nodules on surface of liver parenchyma\n Pancreas\n Pleura\n Stomach\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nNo regional lymph node involvement\n\n
\nCommon bile duct\n Porta hepatis\n Portal\n Cystic duct\n Hepatic, NOS\n Hepatic artery\n Hepatic pedicle\n Hepatoduodenal ligament\n Hilar\n Portal vein\n Periportal\n\n
\nPortocaval (portacaval)\n\n
\nLeft liver (segments 2-4) or lobe of liver not stated\n Gastrohepatic\nInferior phrenic\nRight liver (segments 5-8) or lobe of liver not stated\n Periduodenal\n Peripancreatic\n Pancreaticoduodenal\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\nPosterior mediastinal (tracheoesophageal) including juxtaphrenic nodes\nRenal artery\nRetroperitoneal, NOS\nDistant lymph node(s), NOS\nAortocaval\nAortic (para-aortic, periaortic)\nCardiac\nCaval (inferior vena cava)\nCeliac\nDiaphragmatic, NOS\nLateral (aortic) (lumbar)\nPericardial (pericardiac)\n\n
\nDistant lymph node(s)\nLeft liver (segments 2-4) Pancreaticoduodenal\nPeriduodenal\nPeripancreatic\nRight liver (segments 5-8) Gastrohepatic\nInferior phrenic\n\n
\nCarinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nHepatic artery (common, NOS)\n Portal vein (main, NOS)\nTwo or more extrahepatic organs or structures\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nInvasive tumor confined to\n Lamina propria\n Mucosa, NOS\nSubmucosa (superficial invasion)\n\n
\nMuscularis propria (layer)\n\n
\nConfined to gallbladder, NOS\nLocalized, NOS\n\n
\nPerimuscular connective tissue (peritoneal side)\n WITHOUT involvement of serosa (visceral peritoneum)\nPeritoneal side of gallbladder\n\n
\nPerimuscular connective tissue (hepatic side)\n WITH no extension into liver\nHepatic side of gallbladder\n\n
\nPerimuscular tissue, NOS\n UNKNOWN if liver involved\n\n
\nAmpulla of Vater\n Small intestine, NOS\n Branch(es) of hepatic artery (right or left)\n Branch(es) of portal vein (right or left)\n Duodenum\n Extrahepatic bile duct(s)\n Liver, less than or equal to 2 cm OR distance not stated\n Omentum (greater, lesser, NOS)\n Pancreas\n Serosa (visceral peritoneum)\n\n
\nAbdominal wall\n Colon\n Cystic artery/vein\n Diaphragm\n Liver, greater than 2 cm\n Stomach\n\n
\nNo regional lymph node involvement\n\n
\nCeliac artery\n Portal vein\n Retroperitoneal, NOS\n Superior mesenteric\n Cystic duct (Calot's node)\n Hepatic artery\n Node of foramen of Winslow (omental) (epiploic)\n Pancreaticoduodenal\n Pericholedochal (common bile duct)\n Periduodenal\n Peripancreatic (near head of pancreas only)\n Porta hepatis (portal) (periportal) (hilar) (in hilus of liver)\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), including\n Para-aortic\n Pericaval\n Peripancreatic (along body and tail of pancreas only)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nExtrahepatic bile ducts (including common bile duct)\n\n
\nAmpulla of Vater\n Small intestine, NOS\n Stomach, distal or proximal\n Unilateral branches of hepatic artery (right or left)\n Unilateral branches of portal vein (right or left)\n Colon\n Duodenum, NOS\n Invasion of/through serosa\n Liver\n Omentum, greater or lesser\n Pancreas\n Periductal/perimuscular connective tissue\n Serosa (visceral peritoneum) perforated\n\n
\nHepatic artery (common, NOS)\n Portal vein (main, NOS)\nTwo or more extrahepatic organs or structures\n\n
\nAbdominal wall\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nInvasive tumor confined to\nLamina propria\nMucosa, NOS\nSubmucosa (superficial invasion)\n\n
\nCode 100 plus any involvement of gallbladder\n\n
\nMuscularis propria (layer)\n\n
\nCode 200 plus any involvement of gallbladder\n\n
\nConfined to cystic duct, NOS\nLocalized, NOS\n\n
\nPerimuscular connective tissue (peritoneal side)\n WITHOUT involvement of serosa (visceral peritoneum)\nPeritoneal side of gallbladder\n\n
\nPerimuscular connective tissue (hepatic side)\n WITH no extension into liver\nHepatic side of gallbladder\n\n
\nBeyond wall of cystic duct\n Perimuscular tissue, NOS\n UNKNOWN if gallbladder or liver involved\n\n
\nNo regional lymph node involvement\n\n
\nCystic duct (node of the neck of the gallbladder) (Calot's node)\n Porta hepatis (portal) (periportal) (hilar) (in hilus of liver)\n Portal vein\n Hepatic (artery, NOS)\n Hilar (in hepatoduodenal ligament)\n Node of foramen of Winslow (epiploic) (omental)\n Pancreaticoduodenal\n Pericholedochal (common bile duct)\n Periduodenal\n Peripancreatic (near head of pancreas only)\n Periportal\n\n
\nCeliac (axis) artery\n Para-aortic\n Periaortic\n Pericaval\n Superior mesenteric artery\n Superior mesenteric vein\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Peripancreatic (along body and tail of pancreas only)\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n High-grade biliary intraepithelial neoplasia (BilIn-3)\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nInvasive tumor of perihilar (proximal) bile duct(s) confined to\nLamina propria\nMucosa, NOS\nMuscle layer of fibrous tissue\nMuscularis propria\nSubepithelial connective tissue (tunica mucosa)\nSubmucosa (superficial invasion)\nConfined to perihilar bile duct, NOS\n Localized, NOS\n\n
\nAdipose tissue\n Adjacent (connective) tissue, NOS\n Beyond wall of bile duct\n Periductal/fibromuscular connective tissue\n\n
\nAdjacent hepatic parenchyma\n Liver\n\n
\nColon\n Duodenum\n Gallbladder\n Omentum (greater, lesser, NOS)\n Pancreas\n Stomach\n\n
\nUnilateral branches of hepatic artery (right or left)\n Unilateral branches of portal vein (right or left)\n\n
\nHepatic artery (common, NOS)\n Main portal vein or its branches bilaterally\n Portal vein, NOS\n Second-order biliary radicals bilaterally\n Unilateral second-order biliary radicals with contralateral \n vein or hepatic artery involvement\n\n
\nAbdominal wall\n\n
\nFurther contiguous extension\n\n
\nNo regional lymph node involvement\n\n
\nCholedochal\n Periduodenal\n Peripancreatic (near head of pancreas only)\n Periportal\n Portal\n Common bile duct\n Cystic duct (node of the neck of the gallbladder) (Calot's node)\n Hepatic\n Hepatic artery\n Hilar (porta hepatic) (portal) (in hilus of liver)\n Node of foramen of Winslow (omental) (epiploic)\n Pancreaticoduodenal, posterior\n Pericholedochal (node along common bile duct)\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\nCeliac (axis) artery\nPara-aortic\nPeripancreatic (along body and tail of pancreas only)\nPericaval\nSuperior mesenteric artery\nSuperior mesenteric vein\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n High-grade biliary intraepithelial neoplasia (BilIn-3)\n\n
\nInvasive tumor confined to\n Lamina propria\n Mucosa, NOS\n Muscularis propria\n Submucosa (superficial invasion)\nConfined to distal bile duct, NOS\n Localized, NOS\n\n
\nAdjacent (connective) tissue, NOS\n Unilateral branches of portal vein (right or left)\n Adipose tissue\n Beyond wall of bile duct\n Duodenum\n Gallbladder\n Liver including porta hepatis\n Pancreas\n Periductal/fibromuscular connective tissue\n Unilateral branches of hepatic artery (right or left)\n\n
\nColon\n Hepatic artery (common, NOS)\n Main portal vein or its branches bilaterally\n Omentum (greater, lesser, NOS)\n Stomach (distal, proximal)\n\n
\nAbdominal wall\n Celiac (axis) artery\n Superior mesenteric artery\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nCystic duct (node of neck of gallbladder) (Calot's node)\n Porta hepatis (portal) (hilar) (in hilus of liver)\n Hepatic artery (common, NOS)\n Hilar (in hepatoduodenal ligament)\n Node of foramen of Winslow (omental) (epiploic)\n Pancreaticoduodenal (anterior, posterior)\n Pericholedochal (node along common bile duct)\n Periduodenal\n Peripancreatic (near head of pancreas only)\n Periportal\n\n
\nSuperior mesenteric artery\n Superior mesenteric vein\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\nCeliac\nPara-aortic\nPericaval\nPeripancreatic (along body and tail of pancreas only)\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n\n
\nBlood vessel(s) (major)\nCommon hepatic artery\nCeliac (axis) artery\nSuperior mesenteric artery\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown extension\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nLimited to\n Ampulla of Vater\n Sphincter of Oddi\n\n
\nDuodenal submucosa\n Perisphincteric invasion (invasion beyond sphincter of Oddi)\n\n
\nConfined to ampulla, NOS\nLocalized, NOS\n\n
\nMuscularis propria of duodenum (duodenal wall)\nDuodenum, NOS\n\n
\nPancreas (less than or equal to 0.5 cm)\n\n
\nPancreas (greater than 0.5 cm)\nDuodenal serosa\n\n
\nPeriduodenal soft tissue\n Peripancreatic soft tissue\n\n
\nCommon bile duct\n Extrahepatic bile duct(s)\n Gallbladder\n Hepatic flexure of colon\n Lesser omentum\n Liver (including porta hepatis)\n Pancreas, NOS (depth of invasion not stated)\n Stomach (distal, proximal, NOS)\n Transverse colon\n\n
\nNo regional lymph node involvement\n\n
\n1-3 positive regional lymph node(s)\n\n
\n4 or more regional lymph nodes\n\n
\nRegional lymph node(s), NOS\nLymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n At tail of pancreas\n Para-aortic\n Splenic\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n\n
\nLamina propria\n Mucosa, NOS\n Muscularis propria\n Submucosa (superficial invasion)\nConfined to bile duct, NOS\nLocalized, NOS\n\n
\nAmpulla of Vater\n Small intestine\nInvasion of/through serosa\n Beyond wall of bile duct\n Duodenum\n Gallbladder\n Unilateral branches of the right or left hepatic artery OR portal vein\nLiver, less than or equal to 2 cm or UNKNOWN\n Omentum (greater or lesser)\n Pancreas\n Perimuscular connective tissue\n\n
\nAbdominal wall\nFurther contiguous extension\n Colon\n Common hepatic artery\n Cystic artery/vein\n Hepatic artery, NOS\n Liver greater than 2 cm\n Portal vein or its branches bilaterally\n Portal vein, NOS\n Stomach\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nCeliac\n Cystic duct (node of Calot)\n Node of foramen of Winslow (epiploic) (omental)\n Pancreaticoduodenal\n Pericholedochal (common bile duct)\n Periduodenal\n Peripancreatic (near head of pancreas only)\n Porta hepatis (portal) (periportal) (hilar)\n Superior mesenteric\n\n
\nPara-aortic\n Peripancreatic (along body and tail of pancreas only)\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nInternal carotid artery (encased)\n Masticator space\n Pterygoid plates\n Skull base\n Specified bone (other than mandible, maxilla, palatine)\nFurther contiguous extension\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nGroup 1 WITH depth of invasion (DOI) less than or equal to 5 mm\n OR unknown depth of invasion\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 5 mm and\n less than or equal to 10mm\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 10 mm\n\n
\nGroup 2 WITH depth of invasion (DOI) less than or equal to 5 mm\n OR unknown depth of invasion\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 5 mm and\n less than or equal to 10mm\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 10 mm\n\n
\nInvasion through cortical bone (mandible, maxilla, NOS)\nDeep (extrinsic) muscle of tongue\nGenioglossus\nHyoglossus\nPalatoglossus\nStyloglossus\nTongue muscle (intrinsic)\n Trabecular bone (mandible, maxilla, palatine, NOS)\n\n
\nMaxillary sinus/antrum\n Nasal cavity\n Nose\n Skin of face\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII,\n see EOD Regional Nodes)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n High-grade pancreatic intraepithelial neoplasia (PanIn-3)\n Intraductal papillary mucinous neoplasm with high grade dysplasia\n Intraductal tubulopapillary neoplasm with high grade dysplasia\n Mucinous cystic neoplasm with high-grade dysplasia\n\n
\nAny size tumor\n Confined to pancreas\n Localized, NOS\n\n
\nAny size tumor\nHead of pancreas\n Adjacent stomach\n Gastroduodenal artery\n Transverse colon, including hepatic flexure\nBody and/or tail of pancreas\n Spleen\n Splenic artery/vein\n Splenic flexure\nFixation to adjacent structure(s), NOS\nAll sites\n Ampulla of Vater\n Duodenum\n Extrahepatic bile duct(s)\n Portal vein\n Peripancreatic tissue, NOS\n Stomach\n Superior mesenteric vein\n\n
\nAll Sites\n Aortic artery\n Celiac [axis] artery\n Common hepatic artery\n Superior mesenteric artery\nFurther contiguous extension to other major arteries\n\n
\nAll sites\n Retroperitoneum\n Small intestine (excluding duodenum, see code 500)\n Ureter\nFurther contiguous extension to other organs\nHead of pancreas\n Colon (other than transverse colon including hepatic flexure, see\n code 500)\n Omentum\n Spleen\nBody and/or tail of pancreas\n Adrenal gland/suprarenal gland\n Colon (other than splenic flexure)\n Diaphragm\n Gallbladder\n Kidney\n Liver, including porta hepatis\n Mesenteric fat\n Mesentery\n Mesocolon\n Peritoneum\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nAll sites\n Proximal mesenteric (anterior, posterior)\n Retroperitoneal\n Superior mesenteric\n Superior to head and body of pancreas\nPancreas Head\n Common bile duct (pericholedochal)\n Lateral wall (right)\n Portal vein\n Pyloric, NOS\n Pyloric (infrapyloric, retropyloric, subpyloric, suprapyloric)\n Anterior, NOS\nPancreas Body and Tail\n Gastroepiploic (gastro-omental, left)\n Pancreaticosplenic (pancreaticolineal)\n Splenic (artery, hilum, lineal)\n Suprapancreatic\n Common hepatic artery\n Hepatic, NOS\n Inferior to head and body of pancreas\n Lateral aortic (lumbar)\n Pancreaticoduodenal (anterior, posterior)\n Peripancreatic, NOS\n Posterior, NOS\n\n
\nPancreas Body Tail (C251, C252)\n Celiac\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\nPancreas Head (C250)\n Celiac\nPancreas Body Tail (C251, C252)\n Pericholedochal (common bile duct)\n Porta hepatic\n Pyloric (infrapyloric, retropyloric, subpyloric, suprapyloric\n\n
\nDistant lymph node(s)\nPancreas Head (C250)\n Pancreaticosplenic (pancreaticolienal)\n Splenic (lineal), NOS \n Gastroepiploic (gastro-omental), left\n Splenic artery\n Splenic hilum\n Suprapancreatic\nDistant lymph node(s), NOS\n\n
\nSeeding of peritoneum, even if limited to the lesser sac region\nPositive peritoneal cytology\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n\n
\nInvasion of submucosa\n \nLocalized, NOS\n\n
\nAdjacent connective tissue(s)\n Adjacent organ(s)/structure(s)\n \nRegional Extension, NOS\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nIntra-abdominal\n Paracaval\n Pelvic\n Subdiaphragmatic\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\n \nDistant metastasis WITH or WITHOUT distant lymph node(s)\n \nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nAny size tumor\n Invasive tumor confined to \n Intramucosal, NOS\n Lamina propria (including in a polyp)\n Mucosa, NOS\n Muscularis mucosae (including in a polyp)\n Submucosa (superficial invasion) (including in a polyp)\nConfined to stomach, NOS\nLocalized, NOS\n\n
\nAny size tumor\n Invasion of muscularis propria\n\n
\nExtension through wall, NOS\nInvasion through muscularis propria or muscularis, NOS\nPerimuscular tissue invaded\nSubserosal tissue/(sub)serosal fat invaded\n\n
\nExtension to adjacent (connective) tissue\nWITHOUT perforation of visceral peritoneum covering these structures\nGastric artery\nLigament(s)\n Gastrocolic\n Gastrohepatic\n Gastrosplenic\nOmentum (greater, lesser, NOS)\nPerigastric fat\n\n
\nInvasion of/through\nIleum\nJejunum\nLiver\nPancreas\nSmall intestine, NOS\nSpleen\n Mesothelium\n Serosa\n Tunica serosa\n Visceral peritoneum\nColon/mesocolon (including transverse and flexures)\nDiaphragm\nDuodenum (via serosa)\nEsophagus (via serosa)\n\n
\nAorta\nAbdominal wall\nAdrenal (suprarenal) gland\nCeliac (axis) artery\nKidney\nRetroperitoneum\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nCeliac artery\n Gastropancreatic, left\n Lesser curvature\n Lesser omentum\n Paracardial\nPancreaticosplenic (pancreaticolineal)\nPerigastric, NOS\nPeripancreatic\nPyloric, NOS\n Infrapyloric (subpyloric)\n Suprapyloric\nCommon hepatic artery\nRight gastric (inferior gastric, NOS)\n Gastrocolic\n Gastroduodenal\n Gastroepiploic (gastro-omental), right or NOS\n Gastrohepatic\n Greater curvature\n Greater omentum\n Pancreaticoduodenal\nSplenic (lineal), NOS\n Gastroepiploic (gastro-omental), left\nHepatic, NOS\n Splenic hilar/hilum\nNodule(s) in perigastric fat\nLeft gastric (superior gastric), NOS\n Cardial, NOS\n Cardioesophageal\n Gastric artery\n Gastric, left\n Gastrohepatic\n\n
\nFor lesser curvature only\n Hepatoduodenal\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nLiver (including liver parenchymal nodule(s))\n\n
\nDistant lymph node(s)\nRetropancreatic\nRetroperitoneal\nDistant lymph node(s), NOS\n \nHepatoduodenal (all subsites EXCEPT lesser curvature)\nIntra-abdominal\nMesenteric (inferior, superior, NOS)\nMiddle colic\nPancreaticoduodenal (all subsites EXCEPT greater curvature)\nPara-aortic\nPorta hepatic (portal) (hilar) (in hilus of liver)\n\n
\nAt least one extrahepatic site\n \nWITH or WITHOUT distant lymph node(s)\n \nBone\nLung\nOvary(ies)\nPeritoneum\nOther specified distant metastasis (except liver)\n \nCarcinomatosis\n\n
\nLiver WITH other distant metastasis\n(10) + (20 or 30)\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n\n
\nTumor less than or equal to 1 cm AND confined to\n Intramucosal, NOS\n Lamina propria (including in a polyp)\n Mucosa, NOS\n Muscularis mucosae (including in a polyp)\n Submucosa (superficial invasion) (including in a polyp)\nLocalized, NOS\n\n
\nTumor greater than 1 cm\nOR Invades muscularis propria\n\n
\nExtension through wall, NOS\n Invasion through muscularis propria or muscularis, NOS\n Subserosal tissue/(sub)serosal fat invaded\n Transmural, NOS\n Wall, NOS\n\n
\nAdjacent (connective) tissue(s), NOS (without serosal penetration)\n Ampulla of Vater\n Fat, NOS\n Mesenteric fat\n Mesentery (adjacent loops of bowel)\n Nonperitonealized perimuscular tissue\n Pancreas\n Pancreatic duct\n Retroperitoneum\n\n
\nInvasion of/through serosa (mesothelium) (tunica serosa) (visceral\nExtrahepatic bile duct(s)\nGallbladder\nLiver, including porta hepatis\n peritoneum)\nBlood vessel(s) (major)\n Common hepatic artery\n Portal vein\n Superior mesenteric artery\nCeliac (axis) artery\nColon (hepatic flexure, transverse colon)\nCommon bile duct\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown extension\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nDuodenal\n Gastroduodenal\n Hepatic\n Infrapyloric\n Pancreatoduodenal\n Pericholedochal (common bile duct)\n Pyloric (subpyloric)\n Superior mesenteric\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nLiver\n\n
\nDistant lymph node(s)\n Celiac\n Para-aortic\n Distant lymph node(s), NOS\n\n
\nAt least one extrahepatic site\n Bone\n Lung\n Ovary(ies)\n Peritoneum (seeding)\nDistant metastasis (except liver) WITH or WITHOUT distant\n lymph node(s)\nCarcinomatosis\n\n
\nAny combination of codes 10, 20, or 30\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nUnknown extension\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nTumor less than or equal to 1 cm AND confined to\n Intramucosal, NOS\n Lamina propria (including in a polyp)\n Mucosa, NOS\n Muscularis mucosae (including in a polyp)\n Submucosa (superficial invasion) (including in a polyp)\nLimited to ampulla of Vater or extending to sphincter of Oddi\nLocalized, NOS\n\n
\nTumor greater than 1 cm\nOR Invades muscularis propria\n\n
\nExtension through wall, NOS\nInvasion of/through muscularis propria or muscularis, NOS\nSubserosal tissue/(sub)serosal fat invaded\nTransmural, NOS\nWall, NOS\n\n
\nAdjacent (connective) tissue(s), NOS (without serosal penetration)\nAmpulla of Vater\nFat, NOS\nMesenteric fat\nMesentery (adjacent loops of bowel)\nNonperitonealized perimuscular tissue\nPancreas\nPancreatic duct\nRetroperitoneum\n\n
\nPeriduodenal soft tissue\nPeripancreatic soft tissue\n\n
\nInvasion of/through serosa (mesothelium) (tunica serosa) (visceral\nExtrahepatic bile duct(s)\nGallbladder\nLiver, including porta hepatis\nOmentum (lesser)\nStomach (distal, proximal, NOS)\n peritoneum)\nBlood vessel(s) (major)\n Common hepatic artery\n Portal vein\n Superior mesenteric artery\nCeliac (axis) artery\nColon (hepatic flexure, transverse colon)\nCommon bile duct\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nNo regional lymph node involvement\n\n
\nAnterior to ampulla of Vater\nPancreaticoduodenal\nPeripancreatic (excluding nodes at tail of pancreas)\nPeriportal (portal vein)\nProximal mesenteric\nPyloric (infrapyloric, subpyloric)\nRetroperitoneal\nSuperior mesenteric\nInferior to ampulla of Vater\nPosterior to ampulla of Vater\nSuperior to ampulla of Vater\nCeliac\nHepatic\nHepatic artery\nLateral aortic (lumbar)\nNode of foramen of Winslow (epiploic) (omental)\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nLiver\n\n
\nDistant lymph node(s)\n At tail of pancreas\n Para-aortic\n Splenic\n Distant lymph node(s), NOS\n\n
\nAt least one extrahepatic site\n Bone\n Lung\n Ovary(ies)\n Peritoneum (seeding)\nDistant metastasis (except liver) WITH or WITHOUT distant\n lymph node(s)\nCarcinomatosis\n\n
\nAny combination of codes 10, 20, or 30\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nTumor less than or equal to 1 cm AND confined to\n Intramucosal, NOS\n Lamina propria (including in a polyp)\n Mucosa, NOS\n Muscularis mucosae (including in a polyp)\n Submucosa (superficial invasion) (including in a polyp)\nLocalized, NOS\n\n
\nTumor greater than 1 cm\nOR Invades muscularis propria\nInvasion of muscularis, NOS\n\n
\nInvasion through muscularis propria\nExtension through wall, NOS\nSubserosal tissue/(sub)serosal fat invaded\nTransmural, NOS\nWall, NOS\n\n
\nAdjacent (connective) tissue(s), NOS (without serosal penetration)\nFat, NOS\nMesenteric fat\nMesentery (adjacent loops of bowel)\nNonperitonealized perimuscular tissue\nRetroperitoneum\n\n
\nInvasion of/through serosa (mesothelium) (tunica serosa) (visceral \n peritoneum)\nAbdominal wall\nColon (including appendix)\nOther segments of the small intestine via serosa\nRetroperitoneum invaded greater than 2 cm in depth\n\n
\nBladder\nFallopian tube(s)\nOvary(ies)\nUterus\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nCecal (anterior, retrocecal, NOS)\nCecal (posterior) (terminal ileum only)\nIleocecal\nMesenteric, NOS\nSuperior mesenteric\n\n
\nLarge mesenteric masses (greater than 2 cm)\n Lymph node metastasis greater than 2 cm\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nLiver (including liver parenchymal nodule(s))\n\n
\nDistant lymph node(s)\n Pericholedochal\n Distant lymph node(s), NOS\n\n
\nAt least one extrahepatic site\n \nWITH or WITHOUT distant lymph node(s)\n \nBone\nLung\nOvary(ies)\nPeritoneum (seeding)\nOther specified distant metastasis (except Liver)\n \nCarcinomatosis\n\n
\nLiver WITH other distant metastasis\n(10) + (20 or 30)\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n (Adeno)carcinoma, noninvasive, in a polyp or adenoma\n\n
\nAny size tumor\n Perimuscular tissue\n Subserosa\n Transmural, NOS\n Wall, NOS\nExtension to\n Cecum\nConfined to appendix, NOS\nConfined to muscular wall\nPolyp, NOS\nLocalized, NOS\nInvasive tumor confined to (including polyp [head, stalk, NOS])\n Lamina propria\n Mucosa (intramucosal, NOS)\n Muscularis mucosae\n Submucosa\nInvasion through\n Muscularis propria or muscularis, NOS\n Non-peritonealized pericolic tissues\n\n
\nAny size tumor with extension to\n Pericolic fat\n Serosa\n Adjacent tissue(s), NOS\n Connective tissue\n Fat, NOS\n Ileum\n Mesenteric fat\n Mesentery\n Mesoappendix\n Mesocolon\n\n
\nAbdominal wall\nAdherent to other organs or structures, NOS\nGreater omentum\nRetroperitoneum (excluding fat)\nSmall intestine\n\n
\nAdrenal (suprarenal) gland\nOvary\nUreter\nUterus\nFurther contiguous extension\nBladder\nDiaphragm\nFallopian tube\nFistula to skin\nGallbladder\nKidney\nLiver\nOther segment(s) of colon/rectum via serosa\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nCecal \n Paracolic/pericolic\n Anterior (prececal) \n Posterior (retrocecal)\n Right colic\n Colic, NOS\n Epicolic (adjacent to bowel wall)\n Ileocolic\n Mesenteric, NOS\n Mesocolic, NOS\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nLiver (including liver parenchymal nodule(s))\n\n
\nDistant lymph node(s)\n Inferior mesenteric\n Superior mesenteric\n Distant lymph node(s), NOS\n\n
\nAt least one extrahepatic site\n \nWITH or WITHOUT distant lymph node(s)\n \nBone\nLung\nOvary(ies)\nPeritoneum (seeding)\nOther specified distant metastasis (except liver)\n \nCarcinomatosis\n\n
\nLiver WITH other distant metastasis\n(10) + (20 or 30)\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nAny size tumor with invasion of\n Intramucosa, NOS\n Lamina propria\n Mucosa, NOS\n Muscularis mucosae\n Submucosa (superficial invasion)\nConfined to colon, NOS\nLocalized, NOS\n\n
\nMuscularis propria\n WITH invasion of lamina propria or submucosa\n\n
\nExtension through wall, NOS\nWall, NOS\nInvasion through muscularis propria or muscularis, NOS\n Rectum: WITH intraluminal extension to colon and/or anal\n canal/anus\nNon-peritonealized pericolic tissues invaded\nPerimuscular tissue invaded\nSubserosal tissue/(sub)serosal fat invaded WITHOUT\n penetration overlying serosa\nTransmural, NOS\n\n
\nAdjacent (connective) tissue(s), NOS\nFat, NOS\nGastrocolic ligament (transverse colon and flexures)\nGreater omentum (transverse colon and flexures)\nMesentery (including mesenteric fat, mesocolon)\nPericolic fat\nPerirectal fat\nRectovaginal septum (rectum)\nRetroperitoneal fat (ascending and descending colon)\n\n
\nInvasion of/through\n Diaphragm\n Fallopian tube\n Fistula to skin\n Gallbladder\n Other segment(s) of colon via serosa\n Ovary(ies)\n Retroperitoneum (excluding fat)\n Small intestine\n Uterus\nCecum (C180)\n Mesothelium\n Greater omentum\n Kidney\n Liver\n Ureter\nAscending colon (C182)\n Greater omentum\n Kidney, right\n Liver, right lobe\n Ureter, right\nTransverse colon and flexures (C183, C184, C185)\n Serosa\n Bile ducts\n Gallbladder\n Kidney\n Liver\n Pancreas\n Spleen\n Stomach\nDescending colon (C186)\n Greater omentum\n Kidney, left\n Tunica serosa\n Pelvic wall\n Retroperitoneal fat\n Spleen\n Ureter, left\nSigmoid colon (C187)\n Greater omentum\n Pelvic wall\nRectosigmoid (C199)\n Cul de sac (rectouterine pouch)\n Pelvic wall\n Visceral peritoneum\n Small intestine\nRectum (C209)\n Anus\n Bladder (males only)\n Cul de sac (rectouterine pouch)\n Ductus deferens\n Pelvic wall\n Prostate\n Rectovaginal septum\n Rectovesical fat (males only)\nColon subsites\n Seminal vesicle(s)\n Skeletal muscle(s) of pelvic floor\n Vagina\n Abdominal wall\n Adrenal (suprarenal) gland\n Bladder\n\n
\nColon subsites\n Bladder\n Colon via serosa\n Fallopian tube(s)\n Ovary(ies)\n Prostate\n Skeletal muscle(s) of pelvic floor\n Ureter(s)\n Vagina\nRectum\n Bladder (females only)\n Ovary(ies)\n Bone(s) of pelvis\n Cervix\n Perineum, perianal skin\n Sacrum\n Sacral plexus\n Urethra\nFurther contiguous extension\n Uterus\nTransverse colon and flexures\n Ureter\nSigmoid colon\n Cul de sac (rectouterine pouch)\n Ureter\nRectosigmoid\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nColon subsites\n Ileocolic\n Periappendiceal\n Prececal (anterior, NOS)\n Retrocecal (posterior)\nAscending colon (C182)\n Colic (middle-right branch, right)\n Ileocolic\nHepatic flexure (C183)\n Colic (middle, right)\n Ileocolic\n Colic, NOS\nTransverse colon (C184)\n Colic (left, middle)\nSplenic flexure (C185)\n Colic (left, middle)\n Mesenteric (inferior)\nDescending colon (C186)\n Colic (left)\n Mesenteric (inferior)\n Sigmoid\nSigmoid colon (C187)\n Epicolic (adjacent to bowel wall)\n Colic (left)\n Mesenteric (inferior)\n Rectal (superior) (hemorrhoidal)\n Rectosigmoid\n Sigmoid (sigmoidal) (sigmoid mesenteric)\nRectosigmoid (C199)\n Mesenteric (inferior)\n Mesorectal\n Pericolic\n Perirectal\n Mesenteric, NOS\n Rectal (superior) (hemorrhoidal)\n Sigmoid\nRectum (C209)\n Iliac (internal) (hypogastric)\n Mesenteric (inferior)\n Mesorectal\n Perirectal\n Rectal (inferior, superior) (hemorrhoidal)\n Mesocolic, NOS\n Paracolic\n Pericolic\nCecum (C180)\n Colic (right)\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nLiver (including liver parenchymal nodule(s))\n\n
\nDistant lymph node(s)\nIliac (common, external, hypogastric, internal, obturator)\nRectal, inferior\nSuperior mesenteric\nRectum\nColic (left) (rectum)\nIliac (common, external, NOS)\nSuperior mesenteric\nDistant lymph node(s), NOS\nColon\nIliac (common, external, hypogastric, internal, obturator, NOS)\n Inferior mesenteric (cecum, ascending colon, hepatic flexure, transverse colon)\n Para-aortic\n Retroperitoneal\n Superior mesenteric\nRectosigmoid\nHemorrhoidal, inferior (rectosigmoid)\n\n
\nAt least one extrahepatic site\nCarcinomatosis\n \nWITH or WITHOUT distant lymph node(s)\n \nBone\nLung\nOvary(ies)\nPeritoneal nodule(s)\nPeritoneum (seeding)\nOther specified distant metastasis (excluding liver)\n \n\n
\nLiver WITH other distant metastasis\n(10) + (20 or 30)\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive, intraepithelial\n\n
\nAny size tumor\nConfined to pancreas\nLocalized, NOS\n\n
\nPeripancreatic (adipose) tissue\n Peripancreatic fat\n\n
\nBile duct, NOS\n Common bile duct\n Duodenum\n\n
\nAll sites\nBody and/or tail of pancreas\n Spleen\n Splenic artery/vein\n Splenic flexure\n Superior mesenteric vein\nFixation to adjacent structures, NOS\n Ampulla of Vater\n Portal vein\n Stomach\n Superior mesenteric vein\nHead of pancreas\n Adjacent stomach\n Gastroduodenal artery\n Transverse colon, including hepatic flexure\n\n
\nAll Sites\n Aortic artery\n Celiac [axis] artery\n Common hepatic artery\n Superior mesenteric artery\nFurther contiguous extension to other major arteries\n\n
\nAll sites\n Retroperitoneum\n Small intestine (excluding duodenum, see code 500)\n Ureter\nHead of pancreas\n Colon (other than transverse colon including hepatic flexure, see code 500)\n Omentum\n Spleen\nBody and/or tail of pancreas\n Colon (other than splenic flexure)\n Diaphragm\n Adrenal gland/suprarenal gland\nFurther contiguous extension to other organs\n Gallbladder\n Kidney\n Liver, including porta hepatis\n Mesenteric fat\n Mesentery\n Mesocolon\n Peritoneum\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nAll sites\n Peripancreatic, NOS\n Posterior, NOS\n Proximal mesentery (anterior, posterior)\n Pyloric, NOS\n Retroperitoneal\n Superior to the head and body of pancreas\n Superior mesenteric\nPancreas Head\n Lateral wall (right)\n Portal vein\n Anterior, NOS\n Pyloric (infrapyloric, retropyloric, subpyloric, suprapyloric)\nPancreas Body and Tail\n Pancreaticosplenic (pancreaticolineal)\n Splenic (artery, hilum, lineal)\n Suprapancreatic\n Common bile duct (pericholedochal)\n Common hepatic artery\n Gastroepiploic (gastro-omental, left)\n Hepatic, NOS\n Inferior to the head and body of pancreas\n Lateral aortic (lumbar)\n Pancreaticoduodenal (anterior, posterior)\n\n
\nPancreas Body Tail (C251, C252)\n Celiac\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nHepatic\n Liver\n\n
\nDistant lymph nodes\nPancreas Head (C250)\n Celiac\nPancreas Body Tail (C251, C252)\n Pericholedochal (common bile duct)\n Porta hepatic\n Pyloric (infrapyloric, retropyloric, subpyloric, suprapyloric)\n\n
\nDistant lymph nodes\nPancreas Head (C250)\n Pancreaticosplenic (pancreaticolienal)\n Splenic (lineal), NOS \n Gastroepiploic (gastro-omental), left\n Splenic hilum\n Splenic artery\n Suprapancreatic\nDistant lymph nodes, NOS\n\n
\nExtrahepatic sites, including\n Bone\n Lung\n Ovary\n Peritoneum\nCarcinomatosis\nDistant metastasis (except liver) WITH or WITHOUT distant\n lymph node(s)\n\n
\nHepatic and extrahepatic metastasis\nCode 10 (liver) WITH any combination of codes 20-50\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n\n
\nConfined to thymus (encapsulated tumor)\n No mediastinal or pleura involvement\n\n
\nConfined to thymus (encapsulated tumor)\n Mediastinal or pleural involvement\n\n
\nConfined to thymus, NOS\n Unknown if mediastinum or pleural involved\n\n
\nDirect invasion of pericardium\n\n
\nBrachiocephalic vein\n Chest wall\n Extrapericardial pulmonary artery or vein\n Lung\n Phrenic nerve\n Superior vena cava\n\n
\nAorta (ascending, arch, or descending)\n Arch vessels\n Esophagus\n Intrapericardial pulmonary artery\n Myocardium\n Trachea\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nAscending aorta\n Precricoid/delphian\n Pretracheal\n Prevascular\n Supradiaphragmatic\n Cervical (low anterior)\n Mediastinal (lower, NOS)\n Para-aortic\n Paratracheal, NOS\n Peri-thymic\n Peri-thyroid\n Pericardial\n Phrenic (inferior, superior)\n\n
\nHilar\n Internal mammary\n Lower jugular\n Mediastinal (middle)\n Paratracheal (lower, upper)\n Subaortic/aortopulmonary window\n Subcarinal\n Supraclavicular/venous angle: confluence of internal jugular and\n subclavian vein\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nSeparate pleural or pericardial nodule(s)\n\n
\nDistant lymph node(s), NOS\n\n
\nPulmonary intraparenchymal nodule\nOther extrathoracic sites\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nOR WITH or WITHOUT pleural or pericardial nodule(s) metastasis\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nInvasion of or through cortical bone (maxilla)\n Maxilla, NOS\n Maxillary sinus (antrum)\n Trabecular bone (maxilla)\n\n
\nInternal carotid artery (encased)\n Masticator space\n Pterygoid plates\n Skull base\n Specified bone (other than mandible, maxilla)\nFurther contiguous extension\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nGroup 1 WITH depth of invasion (DOI) less than or equal to 5 mm\n OR unknown depth of invasion\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 5 mm and less than\n or equal to 10mm\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 10 mm\n\n
\nGroup 2 WITH depth of invasion (DOI) less than or equal to 5 mm\n OR unknown depth of invasion\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 5 mm and less than\n or equal to 10mm\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 10 mm\n\n
\nDeep (extrinsic) muscle of tongue\n Genioglossus\n Geniohyoid\n Hyoglossus\n Mylohyoid\n Palatoglossus\n Styloglossus\n\n
\nInvasion through cortical bone (mandible, maxilla, NOS)\n Skin of undersurface of chin/neck\n Trabecular bone (mandible, NOS)\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII, see EOD\n Regional Nodes)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nInvasive tumor confined to trachea\nLocalized, NOS\n\n
\nAdjacent connective tissue\n Recurrent laryngeal nerve\n Subclavian artery(ies)\n Vagus nerve\nAdjacent organ(s)/structure(s)\n Cricoid cartilage\n Esophagus\n Pleura, NOS \n Parietal\n Visceral\n Right and left main bronchi\n Arch of aorta\n Sternum\n Thymus\n Thyroid gland\n Vertebral column\n Azygos vein, right\n Brachiocephalic vein\n Carotid sheath\n Common carotid artery(ies)\n Jugular arch\n Phrenic nerves\n Pretracheal fascia\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nMediastinal, NOS\n Posterior (tracheoesophageal)\nParatracheal\nPretracheal\nTracheal, NOS\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, Noninvasive, intraepithelial\nSquamous cell carcinoma in situ (SCIS)\nAdenocarcinoma in situ (AIS): adenocarcinoma with pure lepidic pattern,\n less than or equal to 3 cm in greatest dimension\n\n
\nAny size tumor\n Adjacent rib\n Rib\n Skeletal muscle\n Sternum\n\n
\nHeart\n Inferior vena cava\n Neural foramina\n Vertebra(e) (vertebral body)\n Visceral pericardium\nSeparate tumor nodule(s) in a different ipsilateral lobe\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nTumor proven by presence of malignant cells in sputum or bronchial\n washings but not visualized by imaging or bronchoscopy; "occult" carcinoma\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nMinimally invasive adenocarcinoma\n Adenocarcinoma tumor\n WITH predominantly lepidic pattern measuring less than or equal\n to 3cm in greatest dimension\n WITH invasive component measuring less than or equal to 5mm\n in greatest dimension\n\n
\nSuperficial spreading tumor, any size\n WITH invasive component limited to bronchial wall\n WITH or WITHOUT proximal extension to main stem bronchus\n (these types of tumors are uncommon)\n\n
\nAny size tumor\n Confined to lung, NOS\n Localized, NOS\n\n
\nAny size tumor\n Adjacent ipsilateral lobe (direct tumor invasion)\n Confined to hilus\n Main stem bronchus, NOS (without involvement of the carina) including\n extension from other part of lung\n\n
\nAny size tumor\n Atelectasis/obstructive pneumonitis \n Extends to hilar region, involving part or all of lung\n Pleura, NOS\n Pulmonary ligament\n Visceral pleura (PL1 or PL2)\n\n
\nAny size tumor\n Brachial plexus, inferior branches or NOS\n Chest wall (thoracic wall) (separate lesion-see EOD Mets)\n Pancoast tumor (superior sulcus syndrome), NOS\n Parietal pericardium\n Parietal pleura (PL3)\n Pericardium, NOS\n Phrenic nerve\nSeparate tumor nodule(s) in the same lobe as the primary\n\n
\nTumor limited to the carina\n\n
\nBlood vessel(s) (major)\nNerve(s)\n Cervical sympathetic (Horner's syndrome)\n Recurrent laryngeal (vocal cord paralysis)\n Vagus\nTrachea\n Aorta\n Azygos vein\n Pulmonary artery or vein\n Superior vena cava (SVC syndrome)\nCarina from lung\nCompression of esophagus or trachea not specified as direct extension\nEsophagus\nMediastinum, extrapulmonary or NOS\n\n
\nNo regional lymph node involvement\n\n
\nIPSILATERAL nodes only\nBronchial\nHilar (bronchopulmonary) (proximal lobar) (pulmonary root)\n Intrapulmonary\n Interlobar\n Lobar\n Segmental\nSubsegmental\nPeri/parabronchial\n\n
\nIPSILATERAL nodes only\n Paraesophageal\n Pulmonary ligament\n Subcarinal\n Posterior (tracheoesophageal)\n Superior mediastinal \n Paratracheal (left, right, upper, low, NOS)\n Prevascular\n Retrotracheal\n Periesophageal\n Pericardial\nCarinal (tracheobronchial) (tracheal bifurcation)\nPeritracheal, NOS\n Azygos (lower peritracheal)\nPrecarinal\nPretracheal, NOS\nMediastinal, ipsilateral or NOS\n Anterior\n Aortic (above diaphragm), NOS \n Peri/para-aortic, NOS \n Ascending aorta (phrenic)\n Subaortic (aortic-pulmonary window)\n Inferior mediastinal \n\n
\nIPSILATERAL or CONTRALATERAL\nLow cervical\nProximal root\nPulmonary root\nScalene (inferior deep cervical)\nSternal notch\nSupraclavicular (transverse cervical)\n\n
\nCONTRALATERAL OR BILATERAL\n Inferior mediastinal \n Paraesophageal\n Pulmonary ligament\n Subcarinal\n Posterior (tracheoesophageal)\n Superior mediastinal \n Paratracheal (left, right, upper, low, NOS)\n Prevascular\n Retrotracheal\nBronchial\nHilar (bronchopulmonary) (proximal lobar) (pulmonary root)\nMediastinal\n Anterior\n Aortic (above diaphragm), NOS \n Peri/para-aortic, NOS \n Ascending aorta (phrenic)\n Subaortic (aortic-pulmonary window)\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nPericardial effusion or pleural effusion (malignant) (ipsilateral,\n contralateral, bilateral, NOS)\nPleural tumor foci or nodules on ipsilateral lung (separate from direct\n extension) or contralateral lung\n Pericardial nodules\nContralateral lung/main stem bronchus\n Contralateral main stem bronchus\n Separate tumor nodule(s) in contralateral lung\n\n
\nSingle distant lymph node involved\n Cervical\n Distant lymph node, NOS\n\n
\nSingle extrathoracic metastasis in a single organ\n\n
\nMultiple extrathoracic metastases in a single organ or in multiple organs\nAbdominal organs\nSkin of chest\nSeparate lesion in chest wall or diaphragm\nMultiple distant lymph node(s)\n Cervical\n Distant lymph node(s), NOS\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nIpsilateral parietal pleura with/without involvement of\n Diaphragmatic pleura\n Mediastinal pleura\n Visceral pleura\nConfined to pleura (mesothelioma), NOS\nLocalized, NOS\n\n
\nIpsilateral pleural surfaces all involved\n Diaphragmatic, parietal, mediastinal, and visceral\nWith involvement of at least one of the following\n Confluent visceral pleural tumor (including any\n involvement of interlobar fissure)\n Contiguous lung involvement, NOS\n Diaphragm (Diaphragmatic muscle)\n Lung parenchyma (direct extension)\n Nodule(s) beneath visceral pleural surface (ipsilateral pleura)\n\n
\nIpsilateral pleural surfaces all involved\n Diaphragmatic, parietal, mediastinal, visceral\nWith involvement of at least one of the following \n Adjacent (connective) tissue, NOS\n Endothoracic fascia\n Mediastinal fat (mediastinal tissues)\n Pericardium, non-transmural or NOS\n Solitary focus of tumor extending into the chest wall\n\n
\nIpsilateral pleural surfaces all involved\n Diaphragmatic, parietal, mediastinal, visceral\nWith involvement at least one of the following\n Chest wall (diffuse extension or multifocal masses of tumor)\n WITH or WITHOUT associated rib destruction\n Mediastinal organs (direct extension)\n Pericardium (extension through to the internal surface\n without pericardial effusion)\n Rib\n\n
\nIpsilateral pleural surfaces all involved\n Pericardium (direct extension through to the internal\n surface with pericardial effusion)\n Peritoneum (direct transdiaphragmatic extension of tumor)\n Spine\nFurther contiguous extension\n Diaphragmatic, parietal, mediastinal, visceral\nWith involvement at least one of the following\n Brachial plexus\n Cervical (neck) tissues\n Contralateral pleura (direct contiguous extension)\n Heart muscle\n Intra-abdominal organs\n Myocardium\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nAortic (above diaphragm), NOS\nIntercostal\nInternal mammary (parasternal)\nIntrapulmonary\n Interlobar\n Lobar\n Segmental\n Subsegmental\nMediastinal, NOS (ipsilateral)\n Anterior\n Posterior (tracheoesophageal)\n Ascending aorta (phrenic)\nPericardial\nPeri/parabronchial\nPeri/paraesophageal (below carina)\nPeri/paratracheal (lower [azygos], upper, NOS)\nPretracheal and retrotracheal (precarinal), NOS\nPrevascular\nPulmonary ligament\n Peri/para-aortic\n Subaortic (aortico-pulmonary window)\nCarinal (tracheobronchial) (tracheal bifurcation)\nHilar (ipsilateral)\n Bronchopulmonary\n Proximal lobar\n Pulmonary root\n\n
\nHilar (contralateral, bilateral)\nScalene (ipsilateral, contralateral)\n Inferior deep cervical\nSupraclavicular (ipsilateral or contralateral)\n Transverse cervical\n Bronchopulmonary\n Proximal lobar\n Pulmonary root\nMediastinal (contralateral, bilateral)\n Anterior\n Posterior (tracheoesophageal)\nPeridiaphragmatic (ipsilateral, contralateral)\n Mediastinal\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nMalignant pleural infusion\n\n
\nDistant lymph node\n Cervical\n Distant lymph node(s), NOS\n\n
\nContralateral lung\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\nContralateral pleura/chest wall (discontinuous involvement)\nLung (discontinuous ipsilateral lung tumors)\nMediastinal organs (discontinuous involvement)\nPeritoneum (discontinuous extension of tumor)\nMesothelioma WITH malignant pleural fluid\nPericardial effusion, malignant\nPleural effusion (see note)\nCarcinomatosis\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nConfined to tissue or organ of origin\nLocalized, NOS\n\n
\nAdjacent connective tissue\n Sternum\n Sympathetic nerve trunk(s)\n Thoracic duct\n Thymus\n Trachea\n Vertebra(e)\nAdjacent organ(s)/structure(s)\n Descending aorta\n Esophagus\n Large (named) artery(ies)\n Large (named) vein(s)\n Pericardium (parietal, visceral [pericardium])\n Phrenic nerve(s)\n Pleura (parietal, visceral, NOS)\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nAortic (above diaphragm), NOS\n Segmental\n Subsegmental\n Mediastinal, NOS\n Anterior\n Posterior (tracheoesophageal)\nPeri/parabronchial\nPericardial\nPeri/paraesophageal\nPeri/paratracheal, NOS\n Azygos (lower peritracheal)\n Peri/para-aortic, NOS \nPre- and retrotracheal, NOS:\n Precarinal\nPulmonary ligament\nSubcarinal\n Ascending aorta (phrenic)\n Subaortic (aortico-pulmonary window)\nCarinal (tracheobronchial) (tracheal bifurcation)\nHilar (bronchopulmonary) (proximal lobar) (pulmonary root)\n Intrapulmonary, NOS\n Interlobar\n Lobar\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nAny size tumor\n \nConfined to cortex of bone\n Extension beyond cortex to periosteum (no break in periosteum)\n \nLocalized, NOS\n\n
\nAny size tumor with extension to\n \n Adjacent bone/cartilage\n Beyond periosteum to surrounding tissues, including adjacent\n skeletal muscle(s)\n\n
\nAny size tumor with extension to\n \n Skin\n\n
\nDiscontinuous tumors in the primary bone site\n \nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nLung\n\n
\nDistant lymph node(s), NOS\n\n
\nBone (other than primary site)\n Lung WITH distant lymph node(s) OR other distant sites\nCarcinomatosis\nDistant mets WITH or WITHOUT distant lymph node(s)\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nInvolvement of one vertebral segments\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nInvolvement of two adjacent vertebral segments\n\n
\nInvolvement of three adjacent vertebral segments\n\n
\nInvolvement of four or more adjacent vertebral segments\n\n
\nConfined to spine, NOS (number of segments involved not known)\n Localized, NOS\n\n
\nInvolvement of nonadjacent vertebral segments\n\n
\nExtension beyond periosteum to surrounding tissues, including adjacent\n skeletal muscle(s)\n\n
\nSpinal canal\n\n
\nGross vascular invasion\n Tumor thrombus in great vessels\n\n
\nNo regional lymph node involvement\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nLung\n\n
\nDistant lymph node(s), NOS\n\n
\nBone (other than primary site)\n Lung WITH distant lymph node(s) OR other distant sites\nCarcinomatosis\nDistant mets WITH or WITHOUT distant lymph node(s)\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nAny size tumor\n One pelvic segment involved AND no extraosseous extension\n\n
\nGross tumor thrombus in major pelvic vessels\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCode 100 WITH extraosseous extension\n Beyond periosteum to surrounding tissues, including adjacent\n skeletal muscle(s)\n\n
\nAny size tumor\n Two pelvic segments involved AND no extraosseous extension\n\n
\nCode 300 WITH extraosseous extension\n Beyond periosteum to surrounding tissues, including adjacent\n skeletal muscle(s)\n\n
\nAt least three pelvic segments involved, NOS\n\n
\nCode 500 WITH extraosseous extension\n Beyond periosteum to surrounding tissues, including adjacent\n skeletal muscle(s)\n\n
\nConfined to pelvis, NOS (number of segments involved not known)\n Localized, NOS\n\n
\nSacroiliac joint\n Sacral neuroforamen\n\n
\nEncasement of external iliac vessels\n\n
\nNo regional lymph node involvement\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nLung\n\n
\nDistant lymph node(s), NOS\n\n
\nBone (other than primary site)\n Lung WITH distant lymph node(s) OR other distant sites\nCarcinomatosis\nDistant mets WITH or WITHOUT distant lymph node(s)\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nAny size tumor\n Confined to site of origin\n Localized, NOS\n\n
\nAny size tumor\n Adjacent connective tissue, NOS\n Adjacent organs/structures, NOS\n Bone/cartilage\n\n
\nCentral compartment viscera\nFacial skeleton\nOrbital invasion\nPterygoid muscles\nSkull base/dural invasion\n\n
\nBrain parenchymal invasion\nCarotid artery encasement\nCentral nervous system involvement via perineural spread\nPrevertebral muscle invasion\nFurther contiguous extension\n\n
\nInvasion of adjacent organ(s)/structure(s), NOS\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nHead and Neck subsites\n Facial (buccinator [buccal], nasolabial, NOS)\n Mandibular (submandibular, submaxillary, submental)\n Parotid, NOS (infra-auricular)\nExternal ear and auditory canal\n Mastoid (posterior, retro-auricular) (occipital)\n Preauricular\nFace, Other (cheek, chin, forehead, jaw, nose, and temple)\n Facial, NOS (buccinator [buccal], nasolabial)\n Mandibular (submandibular, submaxillary, submental)\n Parotid (infra-auricular, preauricular)\n Cervical\n Scalp\n Mastoid (posterior, retro-auricular) (occipital)\n Parotid (infra-auricular, preauricular)\n Spinal accessory (posterior cervical)\nNeck\n Axillary\n Mandibular\n Mastoid (posterior, retro-auricular) (occipital)\n Parotid (infra-auricular, preauricular)\n Spinal accessory (posterior cervical)\nLip\n Submental (bilateral or contralateral)\n Supraclavicular (transverse cervical)\n Buccinator (buccal)\n Facial, NOS\n Mandibular (submandibular, submaxillary, submental)\n Nasolabial\n Parotid (infra-auricular, preauricular)\nEyelid/canthus\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nAny size tumor\n Superficial tumor, NOS\n Deep tumor, NOS\n Confined to site of origin\n Localized, NOS\n\n
\nAny size tumor\n Superficial or deep tumor WITH involvement of \n Adjacent (connective) tissue, NOS\n Adjacent organ(s)/structure(s), NOS\n Major vessel invasion\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nArm/Shoulder\n Cervical\n Internal mammary\n Supraclavicular (transverse cervical)\nLower Trunk\n Superficial inguinal (femoral)\n Axillary\n Epitrochlear for hand/forearm\n Spinal accessory (posterior cervical) for shoulder\nLeg/Hip\n Popliteal for heel and calf\n Superficial inguinal (femoral)\nUpper Trunk\n Axillary\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nConfined to organ, NOS\nLocalized, NOS\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nSerosa\nVisceral peritoneum\n\n
\nBeyond serosa (mesentery)\n\n
\nAdjacent (connective) tissue, NOS\nInto tissue beyond organ\n\n
\nONE adjacent organ/structure invaded\nAdjacent organ(s)/structure(s), NOS\n\n
\nMultifocal involvement of TWO sites\n\n
\nMultifocal involvement of THREE to FIVE sites\n\n
\nMultifocal involvement of MORE than FIVE sites\n\n
\nMultifocal involvement, NOS\nUnknown how many structures involved\n\n
\nNo regional lymph node involvement\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nInternal carotid artery (encased)\nMandible\nMasticator space\nPterygoid plates\nSkull base\nSpecified bone (other than maxilla)\nSphenoid bone\nFurther contiguous extension\n\n
\nUnknown; extension not stated\nPrimary tumor cannot be assessed\nNot documented in patient record\nDeath Certificate Only\n\n
\nGroup 1 WITH depth of invasion (DOI) less than or equal to 5 mm\n OR unknown depth of invasion\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 5 mm and less\n than or equal to 10mm\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 10 mm\n\n
\nGroup 2 WITH depth of invasion (DOI) less than or equal to 5 mm\n OR unknown depth of invasion\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 5 mm and less\n than or equal to 10mm\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 10 mm\n\n
\nInvasion through cortical bone (maxilla, NOS)\n Trabecular bone (maxilla, palatine)\n\n
\nDeep (extrinsic) muscle of tongue\nSkin of face\n Genioglossus\n Hyoglossus\n Palatoglossus\n Styloglossus\nFloor of nose\nMaxillary sinus (antrum)\nNasal cavity\nNasopharynx\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII,\n see EOD Regional Nodes)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nConfined to organ, NOS\n Localized, NOS\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nSerosa\n Visceral peritoneum\n\n
\nBeyond serosa (mesentery)\n\n
\nAdjacent (connective) tissue, NOS\n Into tissue beyond organ\n\n
\nONE adjacent organ/structure invaded\n Large (named) artery(ies) or vein(s)\n Pericardium (parietal, visceral pericardium, NOS)\n Phrenic nerve(s)\n Pleura (parietal, visceral, NOS)\n Sternum\n Sympathetic nerve trunk(s)\n Thoracic duct\n Thymus\n Trachea, parietal pleura\n Vertebra(e)\nAdjacent organ(s)/structure(s), NOS\nPleura (C384)\n Chest wall\n Diaphragm\n Endothoracic fascia\n Heart muscle\n Lung involvement, NOS\n Mediastinal organs or tissues\n Pericardium\n Rib\nHeart (C380)\n Ascending aorta\n Parietal pericardium\n Vena cava\nMediastinum (C381-C383, C388)\n Descending aorta\n Esophagus\n\n
\nMultifocal involvement of TWO structures in code 500\n\n
\nMultifocal involvement of THREE to FIVE structures in code 500\n\n
\nMultifocal involvement of MORE than FIVE sites in code 500\n\n
\nMultifocal involvement, NOS\n Unknown how many structures involved\n\n
\nNo regional lymph node involvement\n\n
\nAll sites\n Peri-/tracheal (lower [azygos], upper, NOS)\n Pretracheal and retrotracheal (precarinal), NOS\n Pulmonary ligament\n Subcarinal\nPleura (C384)\n Hilar (bronchopulmonary) (proximal lobar) (pulmonary root)\n Intrapulmonary, NOS:\n Interlobar\n Lobar\n Segmental\n Aortic (above diaphragm), NOS \n Subsegmental\n Peri/parabronchial\n Precarinal\n Peri/para-aortic, NOS \n Ascending aorta (phrenic)\n Subaortic (aortico-pulmonary window)\n Carinal (tracheobronchial) (tracheal bifurcation)\n Mediastinal (anterior, posterior [tracheoesophageal], NOS)\n Pericardial\n Peri-/paraesophageal\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n All Sites \n Distant lymph nodes, NOS\n Pleura \n Contralateral/bilateral hilar (bronchopulmonary) (proximal\n lobar) (pulmonary root)\n Contralateral/bilateral mediastinal\n Scalene (inferior deep cervical), ipsilateral or contralateral\n Supraclavicular (transverse cervical), ipsilateral or \n\n
\nDistant metastasis, NOS\n Pleural effusion\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s) contralateral\n All Sites \n Distant metastasis, NOS\n Pleura \n Cervical (neck) tissues\n Contralateral lung\n Contralateral pleura\n Intra-abdominal organs\n Peritoneum\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nAny size tumor\nConfined to site of origin\n Localized, NOS\n\n
\nAny size tumor\nAdjacent (connective) tissue, NOS\n\n
\nAny size tumor\n Adherent to organs/structure, NOS\n Extension to organs/structures, NOS\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nRegional lymph node metastases\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nPeritoneal nodule(s)\nLiver parenchymal nodule(s)\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nAny size tumor\n Confined to site of origin\n Localized, NOS\n\n
\nAny size tumor with extension to\n Kidney(s)\n Pancreas\n Vena cava\n Vertebra\nPeritoneum (C481, C482, C488)\n Colon (except ascending and descending colon)\n Esophagus\n Gallbladder\n Liver\n Small intestine\nAll sites\n Spleen\n Stomach\n Adjacent connective tissue, NOS\n Adjacent organs/structures, NOS\n Bone/cartilage\nRetroperitoneum (C480)\n Adrenal(s) (suprarenal gland(s))\n Aorta\n Colon (ascending and descending)\n\n
\nPeritoneum (C481, C482, C488)\n Colon (ascending and descending colon)\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nIntra-abdominal\n Paracaval\n Pelvic\n Subdiaphragmatic\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nAny size tumor\n Superficial tumor, NOS\n Deep tumor, NOS\n Confined to site of origin\n Localized, NOS\n\n
\nAny size tumor\n Superficial or deep tumor WITH involvement of \n Adjacent (connective) tissue, NOS\n Adjacent organ(s)/structure(s), NOS\n Major vessel invasion\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nSkin lesion\n Mucosa (e.g., oral cavity, anus, rectum, vagina, vulva)\n Skin and/or connective tissue\n Viscera (e.g., pulmonary, gastrointestinal tract, spleen, other)\n\n
\nMultiple lesions\n Mucosa (e.g., oral cavity, anus, rectum, vagina, vulva)\n Skin and/or connective tissue\n Viscera (e.g., pulmonary, gastrointestinal tract, spleen, other)\n\n
\nMultiple lesions\n Mucosa plus skin and/or connective tissue\n Viscera plus mucosa\n Viscera plus skin and/or connective tissue\n\n
\nMultiple lesions, visceral plus mucosa plus skin and/or connective tissue\n\n
\nMultiple lesions, NOS\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Multiple lesions, NOS\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo lymph node involvement\n (No clinical adenopathy and either pathologically negative or\n no pathological statement)\n\n
\nClinically enlarged palpable lymph node(s) (adenopathy),\n and either pathologically negative nodes or no pathological statement\n\n
\nNo clinically enlarged palpable lymph node(s) (adenopathy) but\n pathologically positive lymph node(s)\n\n
\nBoth clinically enlarged palpable lymph node(s) (adenopathy) and\n pathologically positive lymph node(s)\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNot applicable: Information not collected for this schema\n\n
\nIn situ, intraepidermal, intraepithelial, noninvasive\n\n
\nConfined to site of origin\n Lesion(s) confined to dermis\n Subcutaneous tissue (through entire dermis)\nLocalized, NOS\n\n
\nDirect extension to\n Bone\n Cartilage\n Fascia\n Skeletal muscle\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node metastasis detected on clinical\nAND/OR radiologic examination, (sentinel node) biopsy\n or lymph node dissection\n\n
\nPATHOLOGICAL ONLY\nIn-transit metastasis present\n WITHOUT lymph node metastasis or UNKNOWN\nDiscontinuous from primary tumor\nLocated between primary tumor and draining regional nodal basin\nOR distal to the primary tumor\n\n
\nPATHOLOGICAL ONLY\n Code 700 WITH lymph node metastasis\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL ONLY\nClinical and/or radiologic exam positive nodes\n WITHOUT biopsy or resection of lymph nodes\n\n
\nCLINICAL ONLY\nClinically positive nodes on core biopsy/FNA\n WITHOUT sentinel lymph node biopsy or resection of lymph nodes\n\n
\nPATHOLOGICAL ONLY\nClinically occult nodes\n WITH positive nodes from sentinel node biopsy\n\n
\nPATHOLOGICAL ONLY\nClinically occult nodes\n WITH positive nodes on lymph node resection\n\n
\nPATHOLOGICAL ONLY\nClinically and/or radiologically positive nodes\n WITH positive nodes on biopsy or lymph node resection\n\n
\nPATHOLOGICAL ONLY\nClinically unknown if positive or negative\n WITH positive nodes on biopsy or lymph node resection\n\n
\nCLINICAL ONLY\nIn-transit metastasis present\n WITHOUT lymph node metastasis or UNKNOWN\nDiscontinuous from primary tumor\nLocated between primary tumor and draining regional nodal basin\nOR distal to the primary tumor\n\n
\nCLINICAL ONLY\n Code 600 WITH lymph node metastasis\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n Axillary (lower trunk)\n Femoral (cephalad/caudal) (upper trunk)\n Iliac (leg/hip)\n Supraclavicular (head and neck, arm/shoulder\n\n
\nMetastasis to (excluding direct extension)\n Bone\n Cartilage\n Fascia\n Skeletal muscle\nSkin or subcutaneous tissue beyond regional lymph node(s)\nUnderlying cartilage\nWITH or WITHOUT distant lymph node(s)\n\n
\nLung WITH or WITHOUT metastasis in codes 10 or 20\n\n
\nDistant metastasis to other visceral sites not in codes 10, 20 or 30\n Visceral metastasis, NOS\n WITH or WITHOUT metastasis in codes 10, 20 or 30\nCarcinomatosis\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepidermal, intraepithelial, noninvasive\n (Basement membrane of the epidermis is intact)\n Clark level I\n\n
\nPapillary dermis invaded\n Clark level II\n\n
\nPapillary-reticular dermal interface invaded\n Clark level III\n\n
\nReticular dermis invaded\n Clark level IV\n\n
\nSkin/dermis, NOS\n Localized, NOS\n\n
\nSubcutaneous tissue (through entire dermis)\n Clark level V\n\n
\nBone\nSkeletal muscle\nUnderlying cartilage\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n Regressed melanoma (complete)\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nFour or more clinically occult (detected by SLN biopsy)\n WITHOUT in-transit, satellite, and/or microsatellite metastasis\n\n
\nFour or more positive WITH 1 or greater clinically detected\n AND/OR matted nodes \n WITHOUT in-transit, satellite, and/or microsatellite metastasis\n\n
\nTwo or more clinically occult or detected\n WITH in-transit, satellite, and/or microsatellite metastasis\n WITH or WITHOUT matted nodes\n\n
\nFour or more involved nodes UNKNOWN how detected\n UNKNOWN if matted nodes \n WITHOUT in-transit, satellite, and/or microsatellite metastasis\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nOne clinically occult (detected by SLN biopsy)\n WITHOUT in-transit, satellite, and/or microsatellite metastasis\n\n
\nOne clinically detected node\n WITHOUT in-transit, satellite, and/or microsatellite metastasis\n\n
\nNo clinically occult or detected nodes\n WITH in-transit, satellite, and/or microsatellite metastasis \n WITH or WITHOUT involved lymph nodes\n\n
\nOne involved node UNKNOWN how detected\n WITHOUT in-transit, satellite, and/or microsatellite metastasis\n\n
\nTwo or three clinically occult (detected by SLN biopsy)\n WITHOUT in-transit, satellite, and/or microsatellite metastasis\n\n
\nTwo or three involved nodes WITH 1 or greater clinically detected\n WITHOUT in-transit, satellite, and/or microsatellite metastasis\n\n
\nOne clinically occult or detected node\n WITH in-transit, satellite, and/or microsatellite metastasis\n\n
\nTwo or three involved nodes UNKNOWN how detected\n WITHOUT in-transit, satellite, and/or microsatellite metastasis\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n Axillary (lower trunk)\n Femoral (cephalad/caudal) (upper trunk)\n Iliac (leg/hip)\n\n
\nBone\nSkeletal muscle (excluding direct extension)\nSkin or subcutaneous tissue beyond regional lymph nodes\nUnderlying cartilage\nWITH or WITHOUT distant lymph node(s) (code 10)\n\n
\nLung WITH or WITHOUT metastasis in codes 10 or 20\n\n
\nDistant metastasis to non-CNS visceral sites\nVisceral metastasis, NOS\nWITH or WITHOUT metastasis to sites in codes 10, 20 or 30\nCarcinomatosis\n\n
\nCNS Metastasis\nWITH or WITHOUT metastasis in codes 10, 20, 30, or 50\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nCarcinoma in situ, noninvasive\n Intraepithelial Bowen disease; intraepidermal\n\n
\nLesion(s) confined to dermis\n Subcutaneous tissue (through entire dermis)\n\n
\nUnderlying cartilage and/or skeletal muscle\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nSkin of trunk (C445) (includes contralateral and bilateral)\nfor contralateral or bilateral nodes)\nSkin of upper limb and shoulder (C446)\nAxillary\nCervical\nEpitrochlear for hand/forearm\nInternal mammary (parasternal)\nSpinal accessory for shoulder\nSupraclavicular (transverse cervical)\nSkin of lower limb and hip (C447)\nFemoral (superficial inguinal)\nUpper trunk \nInguinal\nPopliteal for heel and calf\nAxillary\nCervical\nInternal mammary\nSupraclavicular\nLower trunk \nSuperficial inguinal (femoral) (lower trunk only)\n(C446-C449: Single, Ipsilateral, Multiple. See EOD Mets\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: noninfiltrating; intraepithelial\n Intraductal WITHOUT infiltration\n Lobular neoplasia, grade 3 (LIN 3)\n\n
\nDiagnosis of inflammatory carcinoma\nUlceration of skin of breast\n WITH a clinical description of inflammation, erythema, edema,\n peau d'orange, etc.,\n involving greater than one-third (33%) or more of the skin of the \n breast\n WITH or WITHOUT dermal lymphatic infiltration\nEn cuirasse\nLenticular nodule(s)\nSatellite nodule(s)\n\n
\nStated as "Inflammatory carcinoma" with no other information\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nPaget disease of nipple WITHOUT underlying tumor\n\n
\nPaget disease of nipple WITH underlying DCIS tumor\n\n
\nAny size tumor\nConfined to breast tissue and fat including nipple and/or areola\n Localized, NOS\nEXCLUDES: skin invasion of breast, nipple and areola (see code 200)\n\n
\nAny size tumor\nand/or areola\nAttachment or fixation to pectoral muscle(s) or underlying tumor\n Deep fixation\n Invasion of\nPectoral fascia or muscle(s)\nSubcutaneous tissue\nLocal infiltration of dermal lymphatics adjacent to primary tumor\ninvolving skin by direct extension\nSkin infiltration of primary breast including skin of nipple \n\n
\nInvasion of (or fixation to)\nChest wall\nIntercostal or serratus anterior muscle(s)\nRib(s)\n\n
\nExtensive skin involvement\nSatellite nodule(s)\nSkin edema\nUlceration of skin of breast\n WITHOUT a stated diagnosis of inflammatory carcinoma\n WITH or WITHOUT dermal lymphatic filtration\nEdema of skin\nEn cuirasse\nErythema\nInflammation of skin\nLenticular nodule(s)\nPeau d'orange ("pigskin")\n\n\nDiagnosis of inflammatory carcinoma\nUlceration of skin of breast\n WITH a clinical description of inflammation, erythema, edema, peau\nd'orange, etc.,\n involving less than or equal to one-third (33%) of the skin of the\nbreast or percentage not stated\n WITH or WITHOUT dermal lymphatic infiltration\nEn cuirasse\nSatellite nodule(s)\nSkin edema\n\n
\n300 + (400 OR 450)\n\n
\nNo clinical regional lymph node involvement\n\n
\nCLINICAL assessment only\nFixed/matted axillary (level I and II) (ipsilateral)\n\n
\nCLINICAL assessment only\nInternal mammary node(s), ipsilateral\n WITHOUT axillary (level I and II) lymph node(s), ipsilateral\n\n
\nInfraclavicular lymph node(s) (subclavicular) (level III \n axillary node(s)) (apical), ipsilateral\n WITH or WITHOUT axillary (level I and II) nodes(s)\n WITHOUT internal mammary node\n\n
\nInternal mammary node(s), ipsilateral, clinically apparent\n including infraclavicular\n (On imaging or clinical exam)\n WITH axillary (level I, II, or III) lymph node(s), ipsilateral\n\n
\nSupraclavicular node(s), ipsilateral\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nPATHOLOGICAL assessment only\nITCs only (malignant cell clusters no larger than 0.2 mm) in \n regional lymph node(s)\n\n
\nPATHOLOGICAL assessment only\nPositive molecular findings by reverse transcriptase polymerase \n chain reaction (RT-PCR), no ITCs detected\n\n
\nNo regional lymph node involvement pathologically\n (lymph nodes removed and pathologically negative)\n WITHOUT ITCs or ITC testing unknown\n\n
\nMicrometastasis, less than or equal to 2 mm\n Axillary (level I and II) lymph node(s), ipsilateral\n Detected by IHC or H&E (At least one micrometastasis greater than 0.2mm\n or more than 200 cells)\nMicrometastasis, NOS\n\n
\nCLINICAL assessment only\nClinically positive movable axillary (level I and II) lymph node(s)\n ipsilateral\n Positive needle core biopsy/FNA\n\n
\nPATHOLOGICAL assessment only\nPositive axillary (level I and II) lymph node(s), ipsilateral\n WITH more than micrometastasis\n (At least one metastasis greater than 2 mm, or size of\n metastasis not stated)\nWITHOUT internal mammary lymph node(s) or not stated\n\n
\nPATHOLOGICAL assessment only\nInternal mammary node(s), ipsilateral, positive on sentinel node\n biopsy but not clinically apparent\n (No positive imaging or clinical exam)\n WITHOUT axillary lymph node(s), ipsilateral\n\n
\nPATHOLOGICAL assessment only\nInternal mammary node(s), ipsilateral, positive on sentinel node\n biopsy not clinically apparent\n (No positive imaging or clinical exam)\n WITH axillary lymph node(s), ipsilateral\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nNo clinical or radiographic evidence of distant mets\nTumor cells found in circulating blood, bone marrow or other distant\n lymph node tissue less than or equal to 0.2mm\n\n
\nDistant lymph node(s)\n Axillary (contralateral or bilateral)\n Cervical, NOS\n Fixed/matted axillary (level I and II) (contralateral or bilateral)\n Infraclavicular (subclavicular) (contralateral or bilateral)\n Internal mammary (parasternal) (contralateral or bilateral)\n Intramammary (contralateral or bilateral)\n Supraclavicular (transverse cervical) (contralateral or bilateral)\n Distant lymph node(s), NOS\n\n
\nSkin over\nContralateral (opposite) breast-if stated as metastatic\nLung\nOvary\nSatellite nodule(s) in skin other than primary breast\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n Axilla\n Contralateral (opposite) breast\n Sternum\n Upper abdomen\nFurther contiguous extension\nDistant metastasis\nAdrenal (suprarenal) gland\nBone other than adjacent rib\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepidermal, intraepithelial, preinvasive, noninvasive\n Bowen disease\n\n
\nBladder mucosa\nPerineal body\nRectal mucosa\nUrethra:\n \nUpper/proximal two-thirds\nFIGO Stage IIIA based on extension\n\n
\nFixed to pubic bone (pelvic bone)\n \nFurther contiguous extension\n \nFIGO Stage IVA based on extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\nPrimary tumor cannot be assessed\nNot documented in medical record\n \nDeath Certificate Only\n\n
\nVulva only: Stromal invasion less than or equal to 1 mm\n \nUNKNOWN or NO perineum involvement\nInvasive carcinoma confined to\n \nMusculature\nSubmucosa\nVulva including skin\nFIGO Stage IA\n\n
\nVulva only: Stromal invasion not known\n \nUNKNOWN or NO perineum involvement\nConfined to vulva, NOS\nLocalized, NOS\n \nFIGO Stage I [NOS]\n\n
\nVulva and perineum: Stromal invasion less than or equal to 1 mm\n\n
\nVulva and perineum: Stromal invasion not known\n\n
\nVulva only: Stromal invasion greater than 1 mm\nConfined to\n Musculature\n Submucosa\n Vulva including skin\nFIGO Stage IB\n\n
\nVulva and perineum only: Stromal invasion greater than 1 mm\n\n
\nAdjacent perineal structures\n Lower/distal third of urethra\n Lower/distal third of vagina\nAnus\nPerianal skin\nUrethra, NOS\nVagina, NOS\nFIGO Stage II\n\n
\nBladder wall or bladder, NOS excluding mucosa\n Rectal wall or rectum, NOS excluding mucosa\n Vagina\n Upper/proximal two-thirds\n\n
\nNo regional lymph node involvement\n\n
\nUnknown; regional lymph node(s) not stated\nRegional lymph node(s) cannot be assessed\nNot documented in medical record\n \nDeath Certificate Only\n\n
\nIsolated tumor cells in regional lymph node(s) less than\nor equal to 0.2 mm OR\nSingle cells or clusters of cells less than or equal to 200 cells\nin a single lymph node cross section\n\n
\nNon-fixed, non-ulcerated or UNKNOWN if fixed or ulcerated,\nlymph node involvement and size of metastasis greater than 0.2 mm\nbut less than or equal to 2.0 mm\n\n
\nNon-fixed, non-ulcerated or UNKNOWN if fixed or ulcerated,\nlymph node involvement and size of metastasis greater than 2.0 mm\nbut less than or equal to 5 mm\n \nFIGO Stage IIIA\n\n
\nNon-fixed, non-ulcerated or UNKNOWN if fixed or ulcerated,\nlymph node involvement and size of metastasis greater than 5 mm\n \nFIGO Stage IIIB\n\n
\nNon-fixed, non-ulcerated or UNKNOWN if fixed or ulcerated,\nlymph node involvement with extranodal extension (ENE)\n \nFIGO Stage IIIC\n\n
\nNon-fixed, non-ulcerated or UNKNOWN if fixed or ulcerated,\nlymph node involvement\n \nFIGO Stage III\n\n
\nFixed or ulcerated lymph node involvement\n \nFIGO Stage IVA based on lymph node involvement\n\n
\nRegional lymph node(s), NOS\nLymph node(s), NOS\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\nCommon iliac\nExternal iliac\nInternal iliac (hypogastric) Obturator\n Obturator\nPelvic, NOS\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\nFIGO Stage IVB, IV (NOS)\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nGroup 1 WITH depth of invasion (DOI) less than or equal to 5 mm\n OR unknown depth of invasion\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 5 mm and less\n than or equal to 10mm\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 10 mm\n\n
\nGroup 2 WITH depth of invasion (DOI) less than or equal to 5 mm\n OR unknown depth of invasion\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 5 mm and less\n than or equal to 10mm\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 10 mm\n\n
\nInvasion of or through cortical bone\nGenioglossus\nHyoglossus\nPalatoglossus\nStyloglossus\nMaxillary sinus (antrum)\n Nasal cavity\n Skin of cheek (WITH or WITHOUT ulceration)\n Tongue\nBone, NOS\nCartilage (mandible, maxilla, NOS)\nCortical bone (mandible, maxilla, NOS)\nMandible, NOS\nMaxilla, NOS\nPalatine, NOS\nTrabecular bone (mandible, maxilla, palatine, NOS)\nDeep (extrinsic) muscle of tongue\n\n
\nInternal carotid artery (encased)\n Masticator space\n Pterygoid plates\n Skull base\n Specified bone (other than maxilla, mandible, palatine)\nFurther contiguous extension\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\nMediastinal (excluding superior mediastinal node(s), Level VII\n see EOD Regional Nodes)\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepidermal, intraepithelial, noninvasive\n\n
\nAny size tumor confined to vagina\n Musculature involved\n Submucosa (stroma) (vagina)\nLocalized, NOS\nFIGO Stage I\n\n
\nAny size tumor invading\n \n Cervix\nCul de sac (rectouterine pouch)\nParametrium\nParavaginal soft tissue\nRectovaginal septum\nVesicovaginal septum\nVulva\n\n
\nTumor invading paravaginal soft tissues, NOS (size unknown)\nFIGO Stage II\n\n
\nExtension to lower third of the vagina (from proximal vagina)\nSkeletal portions of bony pelvis\n \nRectal wall or rectum, NOS excluding mucosa\n \nBladder wall or bladder, NOS (excluding mucosa)\n "Frozen pelvis" (clinically diagnosed)\n Hydronephrosis or nonfunctioning kidney\n Pelvic sidewall\nFascia\nMuscle\nNeurovascular structures\n\n
\nFIGO Stage III (NOS)\n\n
\nBladder mucosa (excluding bullous edema)\n Rectal mucosa\n Urethra\nExtension beyond true pelvis\nFurther contiguous extension\nFIGO Stage IVA\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nIsolated tumor cells no greater than 0.2 mm\n\n
\nUpper two thirds of vagina\nSacral\nLower third of vagina (ipsilateral and bilateral)\nFemoral [superficial inguinal]\nInguinal, NOS\nIliac (common, external, NOS)\nInternal iliac (hypogastric)\nMiddle sacral (promontorial) (Gerota's node)\nObturator\nPara-aortic\nParametrial\nPelvic, NOS\nPresacral\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\nObturator\nPara-aortic\nParametrial\nPelvic, NOS\nPresacral\nSacral\nUpper two thirds of vagina\nInguinal, NOS\nSuperficial inguinal (femoral)\n All Sites\nAortic (lateral [lumbar], para-aortic, periaortic, NOS)\nRetroperitoneal, NOS\nDistant lymph node(s), NOS\nLower third of vagina\nIliac (common, external, NOS)\nInternal iliac (hypogastric)\nMiddle sacral (promontorial) (Gerota's node)\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive, preinvasive\nCancer in situ WITH endocervical gland involvement\n \nCervical intraepithelial neoplasia (CIN) Grade III\n\n
\nInvasion beyond uterus, NOS\n \nFIGO Stage II [NOS]\n\n
\nBladder wall\n \nFIGO Stage IIIA\n Bladder, NOS excluding mucosa\n Bullous edema of bladder mucosa\n Lower third of vagina\n Rectal wall\n Rectum, NOS excluding mucosa\n Ureter, intra- and extramural\n Vagina, lower third (not extending to pelvic wall)\n Vulva\n\n
\nDescribed clinically as frozen pelvis\n Hydronephrosis or nonfunctioning kidney\n Pelvic wall(s)\n \nFIGO Stage IIIB\n\n
\nFallopian tube(s)\n Ovary(ies)\n Urethra\n \nFIGO Stage III [NOS]\n\n
\nBladder mucosa (for bullous edema of bladder mucosa, see code 550)\n Rectal mucosa\n Sigmoid colon\n Small intestine\n \nFIGO Stage IVA\n \nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nMeasured stromal invasion 3.0 mm or less\nAND horizontal spread of 7.0 mm or less\n \nFIGO Stage IA1\n\n
\nMeasured stromal invasion 3.1 mm to 5.0 mm\n AND horizontal spread of 7.0 mm or less\n \nFIGO Stage IA2\n\n
\nStromal invasion 5.0 mm or less measured from the base of the epithelium\nAND horizontal spread of 7.0 mm or less\n \nFIGO Stage IA [NOS]\n\n
\nClinically visible lesion (macroscopic), including superficial invasion\n\n
\nLocalized, NOS\n Confined to cervix uteri or uterus, NOS, except corpus uteri, NOS\n (Not clinically visible or unknown if clinically visible)\n \nFIGO Stage IB\n\n
\nCorpus uteri, NOS\n Confined to corpus uteri, size, depth and horizontal spread unknown\n \nFIGO Stage I [NOS]\n\n
\nAny size tumor WITHOUT parametrial (paracervical soft tissue) invasion\n Cul de sac (rectouterine pouch)\nUpper two-thirds of vagina including fornices\nVagina, NOS\nVaginal wall, NOS\n\n
\nLigament(s) (broad, cardinal, uterosacral)\n Parametrial (paracervical soft tissue) invasion\n \nFIGO Stage IIB\n\n
\nNo regional lymph node involvement\n\n
\nIsolated tumor cells\n\n
\nAortic\nParametrial\nPelvic, NOS\nSacral, NOS\n Lateral (laterosacral)\n Middle (promontorial) (Gerota's node)\n Presacral\n Uterosacral\n Lateral aortic\n Para-aortic\n Periaortic\nIliac, NOS\n Common\n External\n Internal (hypogastric) (obturator), NOS\nParacervical\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Inguinal\n Mediastinal\n Scalene\n Supraclavicular\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis, NOS\nFIGO Stage IVB\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive, preinvasive\nEndometrial intraepithelial neoplasia (EIN) (8380/2)\n\n
\nAdnexa (direct extension or metastasis)\nFallopian tube(s)\nOvary(ies)\nSerosa, NOS\nTunica serosa (visceral peritoneum of corpus, serosa covering the corpus)\nTunica serosa of corpus\nFIGO Stage IIIA\n\n
\nBladder, NOS (excluding mucosa)\nVisceral peritoneum of pelvic organs excluding serosa of corpus\nVulva\nDescribed clinically as "frozen pelvis", NOS\nFIGO Stage IIIB\nLigaments (broad, round, uterosacral)\nParametrium, NOS\nParietal serosa of pelvic wall\nPelvic wall(s)\nRectal wall\nRectum, NOS excluding mucosa\nUreter\nVagina (direct extension or metastasis)\n\n
\nFIGO Stage III [NOS]\n\n
\nAbdominal serosa (visceral or parietal peritoneum of abdomen)\nFIGO Stage IVA\nAbdominal structures (other, NOS)\nAbdominal tissue (infiltration)\nBladder mucosa (excluding bullous edema)\nBowel mucosal\nCul de sac (rectouterine pouch or Pouch of Douglas)\nSigmoid colon\nSmall intestine\nFurther contiguous extension\n\n
\nFIGO Stage IV [NOS]\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\nPrimary tumor cannot be assessed\nNot documented in medical record\nDeath Certificate Only\n\n
\nEndometrial intraepithelial carcinoma (EIC) (8380/2)\nSerous endometrial intraepithelial carcinoma (SEIC) (8441/2)\n\n
\nConfined to endometrium (stroma)\nInvasion of inner half of myometrium\nFIGO Stage IA\n\n
\nCode 100 + Endocervical glandular involvement\n\n
\nInvasion of outer half of myometrium\nFIGO Stage IB\n\n
\nCode 200 + Endocervical glandular involvement\n\n
\nInvasion of myometrium, NOS\nInvasive cancer confined to corpus uteri\nLocalized, NOS\nFIGO Stage I [NOS]\n\n
\nCode 300 + Endocervical glandular involvement\n\n
\nCervical stroma invasion\nCervix uteri, NOS\n \nTumor invading the stromal connective tissue of the cervix but not extending beyond the uterus\nFIGO Stage II\n\n
\nNo regional lymph node involvement\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nIsolated tumor cells in regional lymph node(s) no greater than 0.2 mm\n\n
\nPelvic\n Greater than 0.2 mm but not greater than 2.0 mm in diameter\n\n
\nPelvic\n Greater than 2.0 mm in diameter\n\n
\nPelvic\n Diameter of metastasis not known\n\n
\nPara-aortic\n Greater than 0.2 mm but not greater than 2.0 mm in diameter\n\n
\nPara-aortic\n Greater than 2.0 mm in diameter\n\n
\nPara-aortic\n Diameter of metastasis not known\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Deep inguinal, NOS \n Node of Cloquet or Rosenmuller (highest deep inguinal)\n Inguinal, NOS\n Superficial inguinal (femoral)\n Distant lymph node(s), NOS\n\n
\nDistant metastasis\n Bone\n Intraperitoneal disease\n Liver\n Lung\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\nFIGO Stage IVB\n\n
\nDeath Certificate Only\n\n
\nConfined to endometrium (stroma)\nInvasion of myometrium, NOS\nInvasive cancer tumor confined to corpus uteri\nTunica serosa of the visceral peritoneum (serosa covering the corpus)\nLimited to uterus, NOS\nLocalized, NOS\nFIGO Stage IA, IB, I [NOS]\n\n
\nInvasion of organs in code 700 plus infiltration of any abdominal tissues\nExtension to bowel mucosa or bladder (excluding bullous edema)\nCul de sac (rectouterine pouch)\nFIGO Stage IVA, IV [NOS]\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCervical stromal invasion\n Cervix uteri, NOS, but not beyond the uterus\n Endocervical glandular involvement only\n\n
\nExtension or metastasis within true pelvis\n Adnexa, NOS \n Fallopian tube(s)\n Ligaments (broad, round, uterosacral)\n Ovary(ies)\n Parametrium\n Visceral peritoneum of pelvic organs excluding serosa of corpus uteri\nFIGO Stage IIA\n\n
\nParietal serosa of pelvic cavity\n Pelvic wall(s)\n Ureter\n Vagina\n Vulva\nDescribed clinically as "frozen pelvis", NOS\nFIGO Stage II B\n\n
\nExtension beyond uterus, within pelvis, NOS\nFIGO Stage II (NOS)\n\n
\nInfiltration of abdominal tissues, one of the following sites\n Abdominal serosa (visceral or parietal peritoneum of abdomen)\n Sigmoid colon\n Small intestine\n Other abdominal structures\nFIGO Stage IIIA\n\n
\nInfiltration of abdominal tissues (code 550), more than one site\nFIGO Stage IIIB\n\n
\nAbdominal tissues involvement, NOS\nFIGO Stage III (NOS)\n\n
\nInvasion of\n Bladder wall\n Bladder, NOS excluding mucosa\n Rectal wall\n Rectum, NOS excluding mucosa\n\n
\nNo regional lymph node involvement\n\n
\nIsolated tumor cells in regional lymph node(s) no greater than 0.2 mm\n\n
\nAortic (lateral [lumbar], Periaortic, NOS)\n Presacral\n Sacral\n Uterosacral\n Iliac (common, external, internal [hypogastric], NOS)\n Lateral (laterosacral)\n Middle (promontorial) (Gerota's node)\n Obturator\n Para-aortic\n Paracervical\n Parametrial\n Pelvic, NOS\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Deep inguinal, NOS\n Node of Cloquet or Rosenmuller (highest deep inguinal)\n Inguinal, NOS\n Superficial inguinal (femoral)\n Distant lymph node(s), NOS\n\n
\nDistant metastasis\n Bone\n Intraperitoneal disease\n Liver\n Lung\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\nFIGO Stage IVB\n\n
\nDeath Certificate Only\n\n
\nConfined to endometrium (stromal)\nFIGO Stage IA\n\n
\nParietal serosa of pelvic cavity\nPelvic wall(s)\nUreter\nVagina\nVulva\nDescribed clinically as "frozen pelvis", NOS\nFIGO Stage IIB\n\n
\nExtension beyond uterus, within pelvis, NOS\nFIGO Stage II (NOS)\n\n
\nInfiltration of abdominal tissues, one of the following sites\nAbdominal serosa (visceral or parietal peritoneum of abdomen)\nSigmoid colon\nSmall intestine\nOther abdominal structures\nFIGO Stage IIIA\n\n
\nInfiltration of abdominal tissues (see code 550), more than one site\nFIGO Stage IIIB\n\n
\nAbdominal tissues involvement, NOS\nFurther contiguous extension\nFIGO Stage III [NOS]\n\n
\nBladder wall\n Bladder, NOS excluding mucosa\n Rectal wall\n Rectum, NOS excluding mucosa\n\n
\nInvasion of organs in code 700 plus infiltration of any abdominal tissues\nExtension to bowel mucosa or bladder (excluding bullous edema)\nCul de sac\nFIGO Stage IVA, IV [NOS]\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nConfined to endometrium or endocervix (glandular, or glandular and stromal)\n\n
\nTumor invades less than one-half of myometrium\n Invasion of inner half of myometrium\nFIGO Stage IB\n\n
\nInvasion of less than one-half of myometrium\n WITH involvement of endocervix\n\n
\nTumor invades one-half or more of myometrium\n Invasion of outer half of myometrium\nFIGO Stage IC\n\n
\nInvasion of one-half or more of myometrium\n WITH involvement of endocervix\n\n
\nInvasive cancer confined to corpus uteri\n Invasion of myometrium, NOS\n Tunica serosa of visceral peritoneum (serosa covering the corpus)\nLocalized, NOS\n\n
\nInvasion of myometrium, NOS WITH involvement of endocervix\nCervix uteri, NOS, but not beyond uterus\n\n
\nExtension or metastasis within true pelvis\nAdnexa, NOS \nFallopian tube(s)\nLigaments (broad, round, uterosacral)\nOvary(ies)\nParametrium\nVisceral peritoneum of pelvic organs excluding serosa of corpus uteri\nFIGO Stage IIA\n\n
\nNo regional lymph node involvement\n\n
\nIsolated tumor cells in regional lymph node(s) no greater than 0.2 mm\n\n
\nAortic (lateral [lumbar], Periaortic, NOS)\n Presacral\n Sacral\n Uterosacral\n Iliac (common, external, internal [hypogastric], NOS)\n Lateral (laterosacral)\n Middle (promontorial) (Gerota's node)\n Obturator\n Para-aortic\n Paracervical\n Parametrial\n Pelvic, NOS\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Deep inguinal, NOS \n Node of Cloquet or Rosenmuller (highest deep inguinal)\n Inguinal, NOS\n Superficial inguinal (femoral)\n Distant lymph node(s), NOS\n\n
\nDistant metastasis\n Bone\n Intraperitoneal disease\n Liver\n Lung\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\nFIGO Stage IVB\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive, preinvasive\n Limited to tubal mucosa\n\n
\nTumor involves one or both ovaries\nPelvic extension, NOS(below pelvic brim)\nFIGO Stage II [NOS]\n\n
\nMicroscopic peritoneal implants beyond pelvis\n Includes peritoneal surface/capsule of liver\nFIGO Stage IIIA\n\n
\nMacroscopic peritoneal implants beyond pelvis\n Less than or equal to 2 cm in diameter\n Includes peritoneal surface of liver\nFIGO Stage IIIB\n\n
\nMacroscopic peritoneal implants beyond pelvis\n Greater than 2 cm in diameter\n Includes peritoneal surface of liver (liver capsule) \n Includes tumor extension to liver and spleen WITHOUT parenchymal\n involvement of either organ\nFIGO Stage IIIC\n\n
\nOne or both ovaries involved\nWITH confirmed peritoneal metastasis outside of the pelvis (unknown\n whether microscopic or macroscopic)\nPeritoneal implants, NOS\nFurther contiguous extension\nFIGO Stage III [NOS]\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nLimited to one ovary (capsule intact) AND\n No tumor on fallopian tube surface AND\n No malignant cells in ascites or peritoneal washings\nFIGO Stage IA\n\n
\nLimited to both ovaries (capsule(s) intact) AND\n No tumor on fallopian tube surface AND\n No malignant cells in ascites or peritoneal washings\nFIGO Stage IB\n\n
\nLimited to one or both ovaries\n WITH surgical spill\nFIGO Stage IC1\n\n
\nLimited to one or both ovaries\n WITH capsule ruptured before surgery OR\n WITH tumor on ovarian surface or fallopian tube surface\nFIGO Stage IC2\n\n
\nMalignant cells in ascites or peritoneal washings\nFIGO Stage IC3\n\n
\nLimited to one or both ovary(ies)\n UNKNOWN if capsule(s) ruptured\n UNKNOWN if tumor on ovarian surface or fallopian tubes\n UNKNOWN if cells in ascites or peritoneal washings\nLocalized\nFIGO Stage I [NOS]\n\n
\nExtension to or implants on\n Adnexa\n Fallopian tube(s)\n Uterus, NOS\nFIGO Stage IIA\n\n
\nExtension to or implants to other pelvic tissues\nRectosigmoid\nRectum\nSigmoid colon (including sigmoid mesentery)\nUreter (pelvic portion)\nFIGO Stage IIB\nAdjacent peritoneum\nBladder\nBladder serosa\nCul de sac (rectouterine pouch)\nLigament(s) (broad, ovarian, round, suspensory)\nMesovarium\nParametrium\nPelvic wall\n\n
\nNo regional lymph node involvement\n\n
\nIsolated tumors cells no greater than 0.2 mm\n\n
\nLymph node metastasis less than or equal to 10 mm\nFIGO Stage IIIA1i\n\n
\nLymph node metastasis greater than 10 mm\nFIGO Stage IIIA1ii\n\n
\nLymph node metastasis, size unknown\nFIGO Stage IIIAI\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nPleural effusion with positive cytology\nFIGO Stage IVA\n\n
\nDistant lymph node(s)\n Inguinal\n Distant lymph node(s)\nWITH or WITHOUT pleural effusion with positive cytology\n\n
\nExtra-abdominal organs\n Liver parenchymal\n Spleen parenchymal\n Transmural involvement of intestine\nCarcinomatosis (involvement of multiple parenchymal organs OR\ndiffuse involvement of multiple non-abdominal organs)\nWITH or WITHOUT distant lymph node(s) OR pleural effusion with\n positive cytology\nFIGO Stage IVB\n\n
\nDistant metastasis, NOS\nFIGO Stage IV [NOS]\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive, preinvasive\n Limited to tubal mucosa\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nConfined to peritoneum, NOS\n\n
\nExtension to or implants on\n Adnexa\n Fallopian tube(s)\n Ovary(ies)\n Uterus, NOS\nFIGO Stage IIA\n\n
\nExtension to or implants to other pelvic tissues\nRectum\nSigmoid colon (including sigmoid mesentery)\nUreter (pelvic portion)\nFIGO Stage IIB\nBladder\nBladder serosa\nCul de sac (rectouterine pouch)\nLigament(s) (broad, ovarian, round, suspensory)\nMesovarium\nParametrium\nPelvic wall\nRectosigmoid\n\n
\nMicroscopic peritoneal implants beyond pelvis\n Includes peritoneal surface/capsule of liver\n Omentum\n Small intestine\nFIGO Stage IIIA\n\n
\nMacroscopic peritoneal implants beyond pelvis\n Less than or equal to 2 cm in diameter\n Includes peritoneal surface of liver\nFIGO Stage IIIB\n\n
\nMacroscopic peritoneal implants beyond pelvis\n Greater than 2 cm in diameter\n Includes peritoneal surface of liver (liver capsule) \n Includes tumor extension to liver and spleen WITHOUT parenchymal\n Involvement of either organ\nFIGO Stage IIIC\n\n
\nOne or both ovaries or fallopian tubes involved\nOR primary peritoneal cancer\nWITH microscopic confirmed peritoneal metastasis outside of the pelvis\nPeritoneal implants, NOS\nFurther contiguous extension\nFIGO Stage III [NOS]\n\n
\nNo evidence of primary tumor\n\n
\nNo regional lymph node involvement\n\n
\nIsolated tumors cells no greater than 0.2 mm\n\n
\nLymph node metastasis less than or equal to 10 mm\nFIGO Stage IIIA1i\n\n
\nLymph node metastasis greater than 10 mm\nFIGO Stage IIIA1ii\n\n
\nLymph node metastasis, size unknown\nFIGO Stage IIIAI\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nPleural effusion with positive cytology\nFIGO Stage IVA\n\n
\nDistant lymph node(s)\n Inguinal\n Distant lymph node(s)\nWITH or WITHOUT pleural effusion with positive cytology\n\n
\nExtra-abdominal organs\n Liver parenchymal\n Spleen parenchymal\n Transmural involvement of intestine\nCarcinomatosis (involvement of multiple parenchymal organs OR\ndiffuse involvement of multiple non-abdominal organs)\nWITH or WITHOUT distant lymph node(s) OR pleural effusion with\n positive cytology\nFIGO Stage IVB\n\n
\nDistant metastasis, NOS\nFIGO Stage IV [NOS]\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive, preinvasive\n Limited to tubal mucosa\n\n
\nTumor involves one or both fallopian tubes\nPelvic extension, NOS(below pelvic brim)\nFIGO Stage II [NOS]\n\n
\nMicroscopic peritoneal implants or microscopic peritoneal carcinomatosis beyond pelvis (above pelvic brim)\n Includes peritoneal surface/capsule of liver\n Omentum\n Small intestine\nFIGO Stage IIIA\n\n
\nMacroscopic peritoneal implants or macroscopic peritoneal carcinomatosis beyond pelvis\n Less than or equal to 2 cm in diameter\n Includes peritoneal surface of liver\n Omentum\n Small Intestine\nFIGO Stage IIIB\n\n
\nMacroscopic peritoneal implants or macroscopic peritoneal carcinomatosis beyond pelvis (above pelvic brim)\n Greater than 2 cm in diameter\n Includes peritoneal surface of liver (liver capsule) \n Includes tumor extension to liver and spleen WITHOUT parenchymal\n Involvement of either organ\nFIGO Stage IIIC\n\n
\nOne or both fallopian tubes involved\nWITH confirmed peritoneal metastasis or peritoneal carcinomatosis outside of the pelvis (above pelvic brim)\nUNKNOWN if microscopic or macroscopic\nPeritoneal implants, NOS\nFurther contiguous extension\nFIGO Stage III [NOS]\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nLimited to one fallopian tube AND\n No tumor on fallopian tube surface AND\n No malignant cells in ascites or peritoneal washings\nFIGO Stage IA\n\n
\nLimited to both fallopian tubes AND\n No tumor on fallopian tube surface AND\n No malignant cells in ascites or peritoneal washings\nFIGO Stage IB\n\n
\nLimited to one or both fallopian tubes\n WITH surgical spill\nFIGO Stage IC1\n\n
\nLimited to one or both fallopian tubes\n WITH capsule ruptured before surgery OR\n WITH tumor on ovarian surface or fallopian tube surface\nFIGO Stage IC2\n\n
\nMalignant cells in ascites or peritoneal washings\nFIGO Stage IC3\n\n
\nLimited to one or both fallopian tube(s), NOS\n UNKNOWN if capsule(s) ruptured\n UNKNOWN if tumor on ovarian surface or fallopian tubes\n UNKNOWN if cells in ascites or peritoneal washings\nLocalized\nFIGO Stage I (NOS)\n\n
\nExtension to or implants on\n Adnexa\n Corpus uteri\n Ovary(ies)\n Uterus, NOS\nFIGO Stage IIA\n\n
\nExtension to or implants to other pelvic tissues\n Adjacent peritoneum\n Broad ligament, ipsilateral\n Cul de sac (rectouterine pouch)\n Mesosalpinx, ipsilateral\n Rectosigmoid\n Sigmoid\nFIGO Stage IIB\n\n
\nNo regional lymph node involvement\n\n
\nIsolated tumors cells no greater than 0.2 mm\n\n
\nLymph node metastasis less than or equal to 10 mm\nFIGO Stage IIIA1i\n\n
\nLymph node metastasis greater than 10 mm\nFIGO Stage IIIA1ii\n\n
\nLymph node metastasis, size unknown\nFIGO Stage IIIAI\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nPleural effusion with positive cytology\nFIGO Stage IVA\n\n
\nDistant lymph node(s)\n Inguinal\n Distant lymph node(s)\nWITH or WITHOUT pleural effusion with positive cytology\n\n
\nExtra-abdominal organs\nFIGO Stage IVB\n Liver parenchymal\n Spleen parenchymal\n Transmural involvement of intestine\nCarcinomatosis (involvement of multiple parenchymal organs OR\ndiffuse involvement of multiple non-abdominal organs)\n Excludes peritoneal carcinomatosis\nWITH or WITHOUT distant lymph node(s) OR pleural effusion with positive\n cytology\n\n
\nDistant metastasis, NOS\nFIGO Stage IV (NOS)\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n\n
\nConfined to tissue or organ of origin\n Localized, NOS\n\n
\nCorpus uteri\n Fallopian tube for ligaments\n Mesosalpinx, ipsilateral\n Ovary, ipsilateral\n Peritoneum\n Uterus, NOS\n\n
\nCervix uteri\n Cul de sac (rectouterine pouch)\n Omentum\n Ovary, contralateral\n Rectosigmoid\n Sigmoid\n Small intestine\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nAortic, NOS\nInguinal\n Lateral sacral (laterosacral)\n Pelvic, NOS\n Retroperitoneal, NOS\nLateral (lumbar)\nPara-aortic\nPeriaortic\nIliac, NOS\nCommon\nExternal\nInternal (hypogastric) Obturator\nObturator\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ; noninvasive; intraepithelial\n\n
\nConfined to tissue or organ of origin\nLocalized, NOS\n\n
\nAdjacent connective tissue\n Round ligament(s)\n Uterus, NOS\n Vagina\nAdjacent organ(s)/structure(s)\n Adnexa\n Broad ligament(s)\n Cervix uteri\n Corpus uteri\n Fallopian tube(s)\n Ovary(ies)\n Parametrium\n\n
\nOther organ(s) of pelvis\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nGroup 1 WITH depth of invasion (DOI) less than or equal to 5 mm\n OR unknown depth of invasion\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 5 mm and less\n than or equal to 10mm\n\n
\nGroup 1 WITH depth of invasion (DOI) greater than 10 mm\n\n
\nGroup 2 WITH depth of invasion (DOI) less than or equal to 5 mm\n OR unknown depth of invasion\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 5 mm and less\n than or equal to 10mm\n\n
\nGroup 2 WITH depth of invasion (DOI) greater than 10 mm\n\n
\nBone, NOS\nMaxillary antrum (sinus)\nNasal cavity\nSkin of face/neck\nTongue\n Cartilage (mandible, maxilla, NOS)\n Cortical bone (mandible, maxilla, NOS)\nTrabecular bone (mandible, maxilla, palatine, NOS)\nDeep (extrinsic) muscle of tongue\n Genioglossus\n Hyoglossus\n Palatoglossus\n Styloglossus\n\n
\nInternal carotid artery (encased)\nMasticator space\nPterygoid plates\nSkull base\nSpecified bone (other than mandible, maxilla, palatine)\nFurther contiguous extension\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII, see\n EOD Regional Nodes)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nConfined to placenta\nLocalized, NOS\nFIGO Stage 1\n\n
\nCervix\n Corpus uteri\n Uterus, NOS\n\n
\nAdjacent connective tissue, NOS\nOther genital structure(s) by DIRECT EXTENSION or NOS\n Broad ligament(s)\n Fallopian tube(s)\n Genital structure(s), NOS\n Ovary(ies)\n Vagina\nFIGO Stage II\n\n
\nOther genital structure(s) by METASTASIS\nFurther contiguous extension\n Broad ligament(s)\n Cervix uteri\n Corpus uteri\n Fallopian tube(s)\n Genital structure(s), NOS\n Ovary(ies)\n Uterus, NOS\n Vagina\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nAortic, NOS\nParametrial\nPelvic, NOS\nSacral\n Lateral (laterosacral)\n Middle (promontorial) (Gerota's node)\n Presacral\n Uterosacral\n Lateral (lumbar)\n Para-aortic\n Peri-aortic\nIliac, NOS\n Common\n External\n Internal (hypogastric), NOS \n Obturator\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nLung\nFIGO Stage III\n\n
\nDistant lymph node(s)\n Superficial inguinal (femoral)\nDistant lymph node(s), NOS\n\n
\nOther distant metastasis WITH or WITHOUT lung metastasis or\n distant lymph node(s)\nCarcinomatosis\nFIGO Stage IV\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepidermal, intraepithelial, noninvasive\n Bowen disease\n Carcinoma in situ (Penile intraepithelial neoplasia III [PeIN III])\n Erythroplasia of Queyrat\n\n
\nCorpus cavernosum (including tunica albuginea)\n WITHOUT urethral invasion OR UNKNOWN if urethral invasion\n\n
\nCode 500 WITH urethral invasion\n\n
\nMuscle, NOS\n Bulbospongiosus\n Ischiocavernosus\n Superficial transverse perineal\nProstate\nPubic bone\nScrotum\nSkin (abdominal, perineum)\n\n
\nFurther contiguous extension\n Testis\n\n
\nNo evidence of primary tumor\n\n
\nUnknown extension\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNoninvasive localized squamous cell carcinoma\n Noninvasive verrucous carcinoma\n\n
\nVerrucous carcinoma, NOS\n\n
\nLimited to penis\n WITHOUT perineural and/or lymphovascular invasion\n WITH low grade (i.e., grade 1-2) or UNKNOWN grade\n\n
\nCode 100 with high grade (i.e., grade 3 or sarcomatoid)\n\n
\nLimited to penis\n WITH perineural and/or lymphovascular invasion\n WITH or WITHOUT high grade (i.e., grade 3 or sarcomatoid)\n\n
\nLimited to penis\n UNKNOWN perineural and/or lymphovascular invasion\nConfined to penis, NOS\nLocalized, NOS\n\n
\nCorpus spongiosum (including tunica albuginea)\n WITHOUT urethral invasion or UNKNOWN if urethral invasion\n\n
\nCode 400 WITH urethral invasion\n\n
\nNo regional lymph node involvement\n\n
\nCLINICAL ONLY\n Palpable mobile unilateral inguinal lymph node\n\n
\nCLINICAL ONLY\n Palpable mobile greater than or equal to 2 unilateral inguinal nodes\n Bilateral inguinal lymph nodes\n\n
\nCLINICAL ONLY\n Palpable fixed inguinal nodal mass\n Pelvic lymphadenopathy (unilateral or bilateral)\n\n
\nPATHOLOGICAL ONLY\n Positive inguinal lymph nodes WITHOUT extranodal extension\n\n
\nPATHOLOGICAL ONLY\n Extranodal extension of any lymph nodes\n OR pelvic lymph node metastases\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: noninvasive; intraepithelial\n\n
\nLocalized, NOS\n Not known if clinically apparent or inapparent\n\n
\nBladder neck, microscopic invasion\n Extraprostatic extension (beyond prostatic capsule), unilateral,\n bilateral or NOS\n WITHOUT invasion of the seminal vesicles\nExtension to periprostatic tissue WITHOUT invasion of the seminal vesicles\n\n
\nTumor invades seminal vesicle(s)\n\n
\nExtraprostatic tumor that is not fixed\n WITHOUT invasion of adjacent structures\n Periprostatic extension, NOS (unknown if seminal vesicle(s) involved)\n Extraprostatic extension, NOS (unknown if seminal vesicle(s) involved)\n Through capsule, NOS\n\n
\nBladder neck\n Ureter(s)\n Bladder, NOS\n External sphincter\n Extraprostatic urethra (membranous urethra)\n Fixation, NOS\n Levator muscles\n Rectovesical (Denonvillier's) fascia\n Rectum\n Skeletal muscle\n\n
\nExtension to or fixation to pelvic wall or pelvic bone\n "Frozen pelvis", NOS\nFurther contiguous extension including\nOther organs\nPenis\nSigmoid colon\nSoft tissue other than periprostatic\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\n Death Certificate Only\n\n
\nIncidental histologic finding (for example, on TURP) in 5 percent or\n less of tissue resected\n (clinically inapparent)\n\n
\nIncidental histologic finding (for example, on TURP) in more than 5\n percent of tissue resected\n (clinically inapparent)\n\n
\nTumor identified by needle biopsy (clinically inapparent/not palpable)\n Example - for elevated PSA\n\n
\nIncidental histologic finding (for example, on TURP), number of foci\n or percent of involved tissue not specified\n (clinically inapparent/not palpable)\n\n
\nInvolves one-half of one side or less\n (clinically apparent/palpable)\n\n
\nMore than one-half of one side but not both sides\n (clinically apparent/palpable)\n\n
\nInvolves both lobes/sides\n (clinically apparent/palpable)\n\n
\nConfined to prostate, unknown lobe involvement\n (clinically apparent/palpable)\n\n
\nNone\n No regional lymph node involvement\n\n
\nHypogastric\nPresacral\n Iliac, NOS\nExternal\nInternal (hypogastric) (obturator), NOS\nPelvic, NOS\n Periprostatic\n Sacral, NOS\nLateral (laterosacral)\nMiddle (promontory) (Gerota's node)\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\n Death Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Supraclavicular (transverse cervical)\n Distant lymph node(s), NOS\nAortic (lateral [lumbar], para-aortic, periaortic, NOS)\n Cervical\n Common iliac\n Inguinal (deep, NOS)\n Node of Cloquet or Rosenmuller (highest deep inguinal)\nSuperficial (femoral)\nRetroperitoneal, NOS\n Scalene (inferior deep cervical)\n\n
\nBone WITH or WITHOUT distant lymph node(s)\n\n
\nOther metastatic site(s) WITH or WITHOUT bone and/or distant lymph node(s)\nCarcinomatosis\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n Intratubular germ cell neoplasia\n Germ cell neoplasia in situ\n\n
\nNo evidence of primary tumor\n\n
\nUnknown extension\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nFOR PURE SEMINOMAS ONLY\n Tumor less than 3 cm, limited to the testis \n WITHOUT lymphovascular invasion or unknown if lymphovascular invasion\n\n
\nFOR PURE SEMINOMAS ONLY\n Tumor greater than or equal to 3 cm, limited to the testis \n WITHOUT lymphovascular invasion or unknown if lymphovascular invasion\n\n
\nTumor limited to testis WITHOUT lymphovascular invasion or unknown\n Localized, NOS\n if lymphovascular invasion\n Body of testis\n Rete testis\n Surface implants (surface of tunica vaginalis)\n Tunica albuginea\n Tunica vaginalis involved\n Tunica, NOS\n Confined to testis, NOS\n\n
\nTumor limited to testis (including rete testis invasion)\n WITH lymphovascular invasion\n\n
\nEpididymis\n Hilar soft tissue\n Mediastinum (of testis)\n Visceral mesothelial layer\n\n
\nSpermatic cord, ipsilateral\n Vas deferens\n\n
\nDartos muscle, ipsilateral\n Scrotum, ipsilateral\n\n
\nPenis\nScrotum, contralateral\nUlceration of scrotum\nFurther contiguous extension\n\n
\nCLINICAL or PATHOLOGICAL\n No regional lymph node involvement\n\n
\nCLINICAL ONLY\n Metastasis in lymph node(s), all less than 2 cm\n\n
\nPATHOLOGICAL ONLY\n Metastasis in lymph node(s), all less than 2 cm\n\n
\nCLINICAL ONLY\n Metastasis lymph node(s) between 2 cm and 5 cm\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a lymph node, between 2 cm and 5 cm\n\n
\nPATHOLOGICAL ONLY\n Extranodal extension of lymph nodes present\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 5 cm in greatest dimension\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n WITHOUT previous scrotal or inguinal surgery OR UNKNOWN if\n previous scrotal or inguinal surgery \n External iliac\n Pelvic, NOS\n\n
\nDistant lymph node(s)\n WITHOUT previous scrotal or inguinal surgery OR UNKNOWN if\n previous scrotal or inguinal surgery \n Inguinal, NOS\n Deep, NOS\n Node of Cloquet or Rosenmuller (highest deep inguinal)\n Superficial (femoral)\n Retroperitoneal specified as above the diaphragm\n Distant lymph node(s), NOS\n\n
\nLung\n\n
\nOther distant site(s) WITH or WITHOUT distant lymph node(s) and/or lung\nCarcinomatosis\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: intraepithelial, noninvasive\n\n
\nConfined to tissue or organ of origin\nSubcutaneous tissue\nLocalized, NOS\n\n
\nAdjacent connective tissue\n Tunica vaginalis (from other site)\nAdjacent organ(s)/structure(s)\n Epididymis (from other site)\n Penis\n Prostate\n Seminal vesicle (from other site)\n Skeletal muscle (scrotum only)\n Spermatic cord (vas deferens) (from other site)\n Testis\n\n
\nOther organ(s) and structure(s) in male pelvis\n Bladder\n Bone (axial or appendicular skeleton) (scrotum only)\n Rectum\n Underlying cartilage (scrotum only)\n Urethra\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nIliac , NOS\n External\n Internal (hypogastric), NOS \n Obturator\nInguinal , NOS\n Deep inguinal, NOS \n Node of Cloquet or Rosenmuller (highest deep inguinal)\n Superficial inguinal (femoral)\nPelvic , NOS\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nAny size tumor\n Invasion of renal capsule\n Invasive cancer confined to kidney cortex and/or medulla\n Pelvicalyceal system\n Renal pelvis or calyces involved\n Separate focus of tumor in renal pelvis/calyx\nConfined (limited) to the kidney, NOS\nLocalized, NOS\n\n
\nBlood vessel(s) (major)\n Gerota's fascia\nPerinephric tissue invasion WITHOUT extension beyond the\n Gerota's fascia\n Extrarenal portion of renal vein or segmental (muscle\n containing branches)\n Hilar blood vessel\n Perirenal vein\n Renal artery\n Renal vein, NOS\n Tumor thrombus in a renal vein, NOS\nInvasion of perirenal and/or renal sinus fat but not beyond\n\n
\nInferior vena cava (IVC) below diaphragm\n\n
\nIVC above diaphragm or invades wall of IVC\n\n
\nTumor extends into major veins (excluding ipsilateral adrenal gland)\nNot beyond Gerota's fascia (see code 600)\nIVC, NOS\n\n
\nExtension beyond Gerota's fascia to\n Quadratus lumborum muscle\n Retroperitoneal soft tissue\n Tail of pancreas\n Ureter (ipsilateral), including implant(s)\n Adrenal gland (ipsilateral) (contiguous metastasis)\n Ascending colon from right kidney\n Beyond Gerota's fascia, NOS\n Descending colon from left kidney\n Diaphragm\n Duodenum from right kidney\n Peritoneum\n Psoas muscle\n\n
\nAorta\n Liver from right kidney\n Ribs\n Spleen from left kidney\n Stomach\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nNo regional lymph node involvement\n\n
\nAortic, NOS\n Pericaval\n Precaval\n Retrocaval\nRenal hilar\nRetroperitoneal, NOS\n Lateral (lumbar)\n Para-aortic\n Periaortic\n Preaortic\n Retroaortic\nCaval, NOS\n Interaortocaval\n Paracaval\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nExtension to\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n Adrenal gland \n Ipsilateral, noncontiguous\n Contralateral\n Contralateral kidney\n Contralateral ureter\n Liver\n Spleen\nCarcinomatosis\n\n
\nDeath Certificate Only\n\n
\nNoninvasive papillary carcinoma\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\nPrimary tumor cannot be assessed\nNot documented in patient record\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive (flat, sessile)\n\n
\nSubepithelial connective tissue (lamina propria,\n submucosa) of renal pelvis only OR\nSubepithelial connective tissue (lamina propria,\n submucosa) of ureter only\nConfined to renal pelvis, NOS\nConfined to ureter, NOS\nLocalized, NOS\n\n
\nRenal pelvis and ureter (unifocal or multifocal)\n Subepithelial connective tissue \n Renal pelvis from ureter\n Ureter from renal pelvis\n Distal ureter from proximal ureter\nExtension to bladder from ureter\n Subepithelial connective tissue of distal ureter and/or bladder\n\n
\nMuscularis of renal pelvis only OR\nMuscularis of ureter only\n\n
\nCode 200 + 300\nRenal pelvis and ureter (unifocal or multifocal)\n Muscularis \n Distal ureter from proximal ureter\n Renal pelvis from ureter\n Ureter from renal pelvis\nExtension to bladder from ureter\n Muscularis of distal ureter and/or bladder\n\n
\nInvasion beyond muscularis into\n Peripelvic fat (renal pelvis)\n Periureteric fat (ureter)\n Retroperitoneal soft/connective tissue\nFor renal pelvis only\n Ipsilateral kidney parenchyma and kidney, NOS\n\n
\nDuodenum (from right renal pelvis or right ureter)\nIpsilateral adrenal (suprarenal) gland\nMajor blood vessel(s)\n Aorta\n Renal artery/vein\n Vena cava (inferior)\nPsoas muscle (ureter)\nTumor thrombus in a renal vein, NOS\n\n
\nAscending colon (from right renal pelvis or right ureter)\nUterus (ureter)\nSpleen (from left renal pelvis or left ureter)\nFurther contiguous extension\nBladder (wall or mucosa) from renal pelvis\nColon, NOS\nDescending colon (from right renal pelvis or right ureter)\nIpsilateral kidney parenchyma from ureter\nLiver (from right renal pelvis or right ureter)\nPancreas\nPerirenal (perinephric) fat (via kidney)\nProstate (ureter)\n\n
\nNo regional lymph node involvement\n\n
\nSINGLE regional lymph node, less than or equal to 2 cm\n\n
\nSINGLE lymph node greater than 2 cm\n\n
\nMultiple lymph nodes\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nPapillary\n Non-infiltrating\n Transitional cell carcinoma, stated to be non-invasive\n Transitional cell carcinoma, with inferred description of non-invasion\n\n
\nExtension to distal ureter\n Deep muscle or extension through wall of bladder and/or distal ureter\n\n
\nMuscle (muscularis propria) invaded, NOS of bladder only\n\n
\nExtension to distal ureter\n Muscle (muscularis propria) invaded, NOS of bladder and/or distal ureter\n\n
\nExtension to perivesical fat/tissues (MICROSCOPIC) including\n Adventitia\n Distal periureteral tissue\n Periprostatic tissue\n Peritoneum\n Serosa (mesothelium) (to/through)\n Tunica serosa (to/through)\n\n
\nExtravesical mass\nExtension to perivesical fat/tissues (MACROSCOPIC) including\n Adventitia\n Distal periureteral tissue\n Periprostatic tissue\n Peritoneum\n Serosa (mesothelium) (to/through)\n Tunica serosa (to/through)\n\n
\nExtension to perivesical fat/tissues, NOS, including\n Adventitia\n Distal periureteral tissue\n Periprostatic tissue\n Peritoneum\n Serosa (mesothelium) (to/through)\n Tunica serosa (to/through)\n\n
\nExtravesical tumor with extension to\nVagina\nVas deferens\n Parametrium\nProstate, NOS\nProstatic stroma\nRectovesical/Denonvilliers' fascia\nSeminal vesicle\nUreter (excluding distal ureter)\nUrethra (including prostatic urethra)\nUterus\n\n
\nExtravesical tumor with extension to\n Large intestine\n Rectum (male)\n Small intestine\n\n
\nBladder is "fixed"\n\n
\nExtravesical tumor with extension to\n Abdominal wall\n Bone\n Colon\n Pelvic wall\n Pubic bone\n Rectum (female)\nFurther contiguous extension\n\n
\nNonpapillary\n Carcinoma in situ, NOS\n Sessile (flat) (solid) carcinoma in situ\n Transitional cell carcinoma in situ\n\n
\nExtravesical tumor, NOS\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nConfined to mucosa, NOS\n\n
\nLamina propria\n Stroma\n Subepithelial connective tissue\n Submucosa\n Subserosa\n Tunica propria\n\n
\nLocalized, NOS\n\n
\nExtension to distal ureter\n Subepithelial connective tissue of bladder and/or distal ureter\n\n
\nMuscle (muscularis propria) of bladder only\n Superficial muscle - inner half\n\n
\nExtension to distal ureter\n Superficial muscle of bladder and/or distal ureter\n\n
\nMuscle (muscularis propria) of bladder only\n Deep muscle--outer half\nExtension through full thickness of bladder wall\n BUT still contained within bladder wall\n\n
\nNo regional lymph node involvement\n\n
\nSINGLE regional lymph node (excluding common iliac)\n\n
\nMULTIPLE regional lymph nodes (excluding common iliac)\n\n
\nCommon iliac lymph node(s)\n WITH or WITHOUT other regional lymph node(s)\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nIntraaortacaval\n Paracaval\n Superior mesenteric\nDistant lymph node(s), NOS\n\n
\nOther specified distant metastasis\n WITH or WITHOUT distant lymph node(s)\nCarcinomatosis\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nNon-invasive papillary carcinoma\n\n
\nCarcinoma in situ\n\n
\nSubepithelial connective tissue (lamina propria, submucosa) invaded\nLocalized, NOS\n\n
\nMuscularis involved\n\n
\nCorpus spongiosum\n Periurethral muscle (sphincter muscle)\n\n
\nBladder neck\n Corpus cavernosum\n Vagina (anterior, NOS)\n\n
\nAdjacent organ(s), NOS\n Bladder wall\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nSINGLE lymph node involved\n\n
\nMULTIPLE lymph nodes involved\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nNon-invasive papillary carcinoma\n\n
\nCarcinoma in situ involving (WITHOUT stromal invasion)\n Periurethral or prostatic ducts\n Prostatic urethra\n\n
\nSubepithelial connective tissue (lamina propria, submucosa) invaded\nLocalized, NOS\n\n
\nProstate (prostatic stroma)\n Prostatic ducts\n\n
\nBladder neck\n Periprostatic fat (beyond prostate capsule)\n\n
\nAdjacent organ(s), NOS\n Bladder wall\n Extraprostatic invasion bladder wall\n Rectal wall\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nSINGLE lymph node involved\n\n
\nMULTIPLE lymph nodes involved\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nAny size tumor\n Invasive tumor confined to gland/duct of origin\n Multiple foci confined to substance of parotid gland\n Confined to parotid gland, NOS\n Confined to salivary gland, NOS\n Confined to submandibular gland, NOS\n Localized, NOS\n\n
\nAny size tumor\n Extraparenchymal extension, NOS\n Microscopic extraparenchymal extension ONLY to periglandular\n soft/connective tissue\n\n
\nMacroscopic extraparenchymal extension to periglandular soft/connective\n Mylohyoid\n Styloglossus\nFacial artery or vein\nMaxillary artery\nPharyngeal mucosa (parotid gland only)\nSkeletal muscle\n Digastric\n Masseter (parotid gland only)\n Pterygoid\n Sternocleidomastoid (parotid gland only)\n tissue\n Stylohyoid\n Extension to another major salivary gland (parotid, sublingual, \n submandibular, submaxillary)\n submaxillary)\nDeep extrinsic muscles (submandibular gland only)\n Genioglossus\n Geniohyoid\n Hyoglossus\n\n
\nSpinal accessory nerve\n\n
\nEar canal\nSkin overlying gland (parotid gland only)\nExternal auditory meatus (parotid gland only)\nMandible\nMastoid/mastoid process (parotid gland only)\nNerves\n Auricular (parotid gland only)\n Facial (7th nerve) (submandibular and salivary gland only)\n Lingual (submandibular and salivary gland only)\nPeriosteum of mandible\n\n
\nExternal auditory meatus (submandibular and salivary gland only)\nNerves\n Facial (7th nerve) (parotid gland only)\n Lingual (parotid gland only)\nSkin overlying gland (submandibular and salivary gland only)\n\n
\nInternal carotid artery (encased)\n Jugular vein (parotid gland only)\n\n
\nPterygoid plates\n Skull (base, NOS)\nFurther contiguous extension\n\n
\nNo regional lymph node involvement\n\n
\nPATHOLOGICAL ONLY\n Metastasis in MULTIPLE ipsilateral, contralateral, or bilateral nodes\n Extranodal extension (ENE) positive for any node\n\n
\nPATHOLOGICAL ONLY\n Single contralateral node (any size)\n Extranodal extension (ENE) positive\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a SINGLE ipsilateral lymph node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nPATHOLOGICAL ONLY\n Metastasis in SINGLE ipsilateral node\n 3 cm or smaller in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in SINGLE ipsilateral node\n Larger than 3 cm but not larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in MULTIPLE ipsilateral nodes\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative or unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in bilateral or contralateral lymph node(s)\n No nodes larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL or PATHOLOGICAL\n Metastasis in a lymph node larger than 6 cm in greatest dimension\n Extranodal extension (ENE) negative OR unknown\n\n
\nCLINICAL ONLY\n Metastasis in any lymph node(s) with clinically overt ENE\n\n
\nPATHOLOGICAL ONLY\n Metastasis in a SINGLE ipsilateral node\n Larger than 3 cm in greatest dimension\n Extranodal extension (ENE) positive\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s)\n Mediastinal (excluding superior mediastinal node(s), Level VII)\n Distant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive (flat, sessile)\n Noninvasive papillary, polypoid or verrucous carcinoma\n\n
\nLamina propria\n Muscularis\n Subepithelial connective tissue\n Submucosa\nLocalized, NOS\n\n
\nBeyond prostate capsule\n Bladder neck\n Corpus cavernosum\n Corpus spongiosum\n Periurethral muscle (sphincter)\n Prostate\n Vagina, anterior or NOS\n\n
\nOther adjacent organ(s), including\n Bladder (excluding bladder neck)\n Seminal vesicle(s)\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nIliac, NOS\nPelvic, NOS\nSacral, NOS\n Presacral\n Common\n External\n Internal (hypogastric), NOS \n Obturator\nInguinal, NOS\n Deep inguinal, NOS \n Node of Cloquet or Rosenmuller (highest deep inguinal)\n Superficial (femoral)\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepidermal, intraepithelial, noninvasive\n Bowen disease\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nLesion(s) confined to dermis\n Minimal infiltration of dermis\n Subcutaneous tissue (through entire dermis)\n Underlying orbicularis muscle\nLocalized, NOS\n\n
\nEyelid margin\n Tarsal plate\n Tarsus\n\n
\nFull eyelid thickness\n\n
\nBulbar conjunctiva\n Intraorbital structures, NOS\n Ocular structures\n Sclera\n Soft tissues of orbit\n\n
\nBone/periosteum of orbit\n Bony walls of orbit (invades or evades through)\n Lacrimal sac\n Skeletal muscle (except orbicularis muscle in eyelid)\n Underlying cartilage\n\n
\nBrain\n Central nervous system (CNS)\n Nasal cavity\n Nasolacrimal duct\n Other craniofacial structures\n Paranasal sinus\nFurther contiguous structures, NOS\n\n
\nAdjacent structure(s), NOS\n\n
\nNo evidence of primary tumor\n\n
\nNo regional lymph node involvement\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nSINGLE ipsilateral lymph node (less than or equal to 3 cm in\n greatest dimension)\nbased on clinical evaluation or imaging findings\n\n
\nSINGLE ipsilateral lymph node (less than or equal to 3 cm in\n greatest dimension)\nbased on lymph node biopsy\n\n
\nSINGLE ipsilateral lymph node (less than or equal to 3 cm in\n greatest dimension)\nunknown how determined\n\n
\nSINGLE ipsilateral lymph node (greater than 3 cm in greatest\n dimension) or\nMULTIPLE ipsilateral lymph nodes based on clinical evaluation\n or imaging findings\n\n
\nSINGLE ipsilateral lymph node (greater than 3 cm in greatest \n dimension) or\nMULTIPLE ipsilateral lymph nodes based on lymph node biopsy\n\n
\nSINGLE ipsilateral lymph node (greater than 3 cm in greatest \n dimension) or\nMULTIPLE ipsilateral lymph nodes, unknown how determined\n\n
\nSupraclavicular, NOS\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nMetastatic skin lesions with or without distant lymph node(s)\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s), NOS\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\nCIN III (conjunctival intraepithelial neoplasia III)\nSIN III (squamous intraepithelial neoplasia III)\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nTumor confined to one subsite of conjunctiva\n Bulbar conjunctiva\n Forniceal conjunctiva\n Palpebral conjunctiva\n Tarsal conjunctiva\nTumor confined to conjunctiva, NOS\n WITHOUT invasion of adjacent structures\nLocalized, NOS\n\n
\nCornea (3, 6, 9, or 12 o'clock hours)\n Intraocular compartments\n Intraocular extension\n\n
\nMore than one subsite of conjunctiva involved\nAdjacent extraocular extension, excluding orbit\n Anterior eyelid lamella\n Caruncle\n Eyelid margin (lower and/or upper)\n Lacrimal punctum and canaliculi (lower and/or upper)\n Plica\n Posterior eyelid lamella\n\n
\nOrbital soft tissues WITHOUT bone invasion\n\n
\nBone\nBone of orbit\n\n
\nAdjacent paranasal sinuses\n\n
\nBrain\nSinus\nFurther coniguous extension\n\n
\nOrbit, NOS\n\n
\nNo regional lymph node involvement\n\n
\nCervical, NOS\nMandibular, NOS\n Submandibular (submaxillary)\nParotid, NOS\n Infra-auricular\n Preauricular\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certicate Only\n\n
\nIn situ, intraepithelial, noninvasive\n Melanoma confined to the conjunctival epithelium (in situ)\n\n
\nCLINICAL assessment only\n Caruncular tumor\n AND greater than 1 quadrant of nonbulbar conjunctiva (forniceal\n palpebral, tarsal) involved\n\n
\nCLINICAL assessment only\nTumor(s) of nonbulbar (forniceal, palpebral, tarsal) involved, NOS\n WITH corneal extension\nPATHOLOGICAL assessment only\nInvolvement of caruncle WITH extension to cornea\n\n
\nInvasion of globe\n\n
\nInvasion of eyelid\n\n
\nInvasion of orbit\n\n
\nInvasion of\n Lacrimal sac\n Nasolacrimal duct\n Paranasal sinuses\n\n
\nInvasion of sinus, NOS\n\n
\nLocal invasion, NOS\n\n
\nInvasion of the central nervous system\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nCLINICAL assessment only\nLess than or equal to one quadrant involved\nPATHOLOGICAL assessment only\nBulbar conjunctiva tumor with invasion of substantia propria, less than or\n equal to 2.0 mm in thickness\n\n
\nUnknown; extension note stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL assessment only\nGreater than 1 quadrant and less than or equal to 2 quadrants involved\nPATHOLOGICAL assessment only\nBulbar conjunctiva tumor with invasion of substantia propria,\n greater than 2.0 mm in thickness\n\n
\nCLINICAL assessment only\n Greater than 2 quadrants and less than or equal to 3 quadrants involved\n\n
\nCLINICAL assessment only\n Greater than 3 quadrants involved\n\n
\nTumor(s) of bulbar conjunctiva, NOS\n Localized, NOS\n\n
\nCLINICAL assessment only\nNoncaruncular tumor\n AND less than or equal to 1 quadrant of nonbulbar conjunctiva involved\nPATHOLOGICAL assessment only\nNonbulbar conjunctiva tumor with invasion of substantia propria, less\n than or equal to 2.0 mm in thickness\n WITH or WITHOUT involvement of caruncle\n\n
\nCLINICAL assessment only\nNoncaruncular tumor\n AND greater than 1 quadrant of nonbulbar conjunctiva (forniceal,\n palpebral, tarsal) involved\nPATHOLOGICAL assessment only\nNonbulbar conjunctiva tumor with invasion of substantia propria,\n greater than 2.0 mm in thickness\n WITH or WITHOUT involvement of caruncle\n\n
\nCLINICAL assessment only\nCaruncular tumor\n AND less than or equal to 1 quadrant of nonbulbar conjunctiva (forniceal,\n palpebral, tarsal) involved\n\n
\nNo regional lymph node involvement\n\n
\nCervical, NOS\nMandibular, NOS\n Submandibular (submaxillary)\nParotid, NOS\n Infra-auricular\n Postauricular\n Preauricular\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nTumor confluent with or extending into ciliary body, choroid or both\n WITH scleral extension\n\n
\nTumor WITH extrascleral extension\n LESS than or equal to 5 mm in diameter\n\n
\nTumor WITH extrascleral extension\n MORE than 5 mm in diameter\n\n
\nTumor WITH extrascleral extension\n Measurement of diameter not specified\nAdjacent extraocular extension\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nLimited to iris not more than 3 clock hours in size\n\n
\nLimited to iris more than 3 clock hours in size\n\n
\nLimited to iris WITH melanomalytic (secondary) glaucoma\n\n
\nLimited to iris, NOS\nLocalized, NOS\n\n
\nTumor confluent with or extending into ciliary body\n WITHOUT secondary glaucoma\n\n
\nTumor confluent with or extending into ciliary body AND choroid\n WITHOUT secondary glaucoma\n\n
\nTumor confluent with or extending into ciliary body, choroid or both\n WITH secondary glaucoma\n\n
\nTumor confluent with or extending into ciliary body, choroid or both\n Presence of secondary glaucoma unknown\n\n
\nNo regional lymph node involvement\n\n
\nCervical, NOS\nMandibular, NOS\n Submandibular (submaxillary)\nParotid, NOS\n Infra-auricular\n Preauricular\n\n
\nDiscrete tumor deposit(s) in orbit not contiguous to the eye\n WITHOUT positive regional lymph node(s)\n\n
\nPositive regional lymph node(s)\n Unknown if discrete tumor deposit(s) in orbit\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nSize of distant metastasis less than 3 cm\n\n
\nSize of distant metastasis 3.1 cm to 8 cm\n\n
\nSize of distant metastasis greater than 8.1 cm\n\n
\nSize of distant metastasis unknown\nDistant lymph node(s), NOS\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: intraepithelial, noninvasive\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nAny tumor size category\n UNKNOWN if ciliary body involvement OR extraocular extension\nLocalized, NOS\n\n
\nAny tumor size category\n WITHOUT ciliary body involvement AND extraocular extension\n\n
\nAny tumor size category\n WITH ciliary body involvement\n\n
\nAny tumor size category\n WITH extraocular extension less than or equal to 5 mm in largest diameter\nNONE or UNKNOWN if ciliary body involvement\n\n
\nAny tumor size category\n WITH ciliary body involvement\n AND extraocular extension less than or equal to 5 mm in largest diameter\n\n
\nExtraocular extension GREATER than 5 mm\n\n
\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nNo regional lymph node involvement\n\n
\nCervical, NOS\nMandibular, NOS\n Submandibular (submaxillary)\nParotid, NOS\n Infra-auricular\n Preauricular\n\n
\nDiscrete tumor deposit(s) in orbit not contiguous to the eye\n WITHOUT positive regional lymph node(s)\n\n
\nPositive regional lymph node(s)\n Unknown if discrete tumor deposit(s) in orbit\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nSize of distant metastasis less than or equal to 3 cm\n\n
\nSize of distant metastasis 3.1 cm to 8 cm\n\n
\nSize of distant metastasis greater than or equal to 8.1 cm\n\n
\nSize of distant metastasis unknown\nDistant lymph node(s), NOS\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nCLINICAL diagnosis only\nIntraretinal tumor(s) with subretinal fluid\n Equal to but not greater than 3 millimeter (mm)\n AND Location not closer than 1.5 mm to optic disk or fovea\n\n
\nCLINICAL diagnosis only\nAdvanced intraocular tumor(s) WITH\n Phthisis or pre-phthisis bulbi\n\n
\nPATHOLOGICAL diagnosis only\nIntraocular tumor(s) WITH significant local invasion\n Massive choroidal invasion (greater than 3 mm [0.3 cm] in\n largest diameter)\n OR multiple foci or focal choroidal involvement (greater than 3 mm)\n OR full-thickness choroidal involvement\n\n
\nCLINICAL diagnosis only\nAdvanced intraocular tumor(s) WITH invasion of\n Anterior chamber\n Choroid\n Ciliary body\n Iris\n Lens\n Pars plana\n Zonules\n\n
\nPATHOLOGICAL diagnosis only\nIntraocular tumor(s) WITH significant local invasion\n Retrolaminar invasion of optic nerve head\n NOT involving transected end of optic nerve\n\n
\nCLINICAL diagnosis only\nAdvanced intraocular tumor(s) WITH\n Raised intraocular pressure with neovascularization\n AND/OR buphthalmos\n\n
\nPATHOLOGICAL diagnosis only\nIntraocular tumor(s) WITH significant local invasion\n Any partial-thickness involvement of sclera within inner two thirds\n\n
\nCLINICAL diagnosis only\nAdvanced intraocular tumor(s) WITH\n Hyphema AND/OR massive vitreous hemorrhage\n\n
\nPATHOLOGICAL diagnosis only\nAdvanced intraocular tumor(s) WITH\n Full-thickness invasion into outer third of sclera\n AND/OR invasion into or around emissary channels\n\n
\nCLINICAL diagnosis only\nAdvanced intraocular tumor(s) WITH\n Aseptic orbital cellulitis\n\n
\nCLINICAL OR PATHOLOGICAL\n Advanced intraocular tumor(s) WITH significant local invasion\n\n
\nCLINICAL diagnosis only\nIntraretinal tumor(s) with subretinal fluid\n Greater than 3 millimeter (mm)\n AND Location closer than 1.5 mm from disc or fovea\n\n
\nCLINICAL diagnosis only\nExtraocular tumor(s) involving orbit\n Radiologic evidence of retrobulbar optic nerve involvement\n OR thickening of optic nerve and/or orbital tissues\n\n
\nCLINICAL diagnosis only\nExtraocular tumor(s) involving orbit, including optic nerve\n WITH proptosis AND/OR an orbital mass\n\n
\nCLINICAL diagnosis only\n Extraocular tumor(s) involving orbit, including optic nerve, NOS\n\n
\nPATHOLOGICAL diagnosis only\n Extraocular muscle\n Eyelids\nEvidence of extraocular tumor\n Tumor at transected end of optic nerve\n Tumor in the meningeal spaces around optic nerve\nFull-thickness invasion of sclera WITH invasion of\n Adjacent adipose tissue\n Bone\n Conjunctiva\n Episclera\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nCLINICAL diagnosis only\nIntraretinal tumor(s) with subretinal fluid =5 mm from the base of any tumor\nTumor confined to retina, NOS\nLocalized, NOS\n\n
\nPATHOLOGICAL diagnosis only\nIntraocular tumor(s) WITHOUT any\n Local invasion\n Focal choroidal invasion\n Pre- or intralaminar involvement of the optic nerve head\nTumor confined to retina, NOS\nLocalized, NOS\n\n
\nCLINICAL diagnosis only\nIntraocular tumor(s) WITH\n Subretinal fluid greater than 5 mm [0.5 cm] from base of tumor\n WITH or WITHOUT retinal detachment\n\n
\nCLINICAL diagnosis only\nIntraocular tumor(s) WITH\n Vitreous seeding and/or subretinal seeding\n WITH or WITHOUT retinal detachment\n\n
\nPATHOLOGICAL diagnosis only\nIntraocular tumor(s) WITH local invasion\n Concomitant focal choroidal invasion\n AND pre- or intralaminar involvement of optic nerve head\n\n
\nPATHOLOGICAL diagnosis only\nIntraocular tumor(s) WITH local invasion\nStromal invasion iris\n AND/OR trabecular meshwork\n AND/OR Schlemm's canal\n\n
\nCLINICAL or PATHOLOGICAL\nIntraocular tumor(s) WITH local invasion, NOS\nIntraocular tumor(s) with retinal detachment, vitreous seeding, or\n subretinal seeding, NOS\n\n
\nNo regional lymph node involvement\n\n
\nCervical, NOS\nMandibular, NOS\n Submandibular (submaxillary)\nParotid, NOS\n Infra-auricular\n Preauricular\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nDistant metastasis to any organ EXCEPT CNS\nCarcinomatosis\nCode 10 + 30\n\n
\nCNS parenchyma\nCerebrospinal fluid\nAny combination of codes 10, 30 and 50\n\n
\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ, intraepithelial, noninvasive\n\n
\nTumor of any size\n WITH or WITHOUT extraglandular extension into the orbital soft tissue\n No periosteal or orbital bone involvement or UNKNOWN if involved\nLocalized, NOS\n\n
\nTumor of any size\n Periosteal involvement only\n\n
\nTumor of any size\n Periosteal and bone involvement\n\n
\nInvolvement of adjacent structures, including\n Brain\n Cavernous sinus\n Orbital bone\n Periosteum\n Pterygoid fossa\n Sinuses\n Superior orbital fissure\n Temporal fossa\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nCervical, NOS\nMandibular, NOS\n Submandibular (submaxillary)\nParotid, NOS\n Infra-auricular\n Preauricular\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n\n
\nConfined to lacrimal sac\n \nLocalized, NOS\n\n
\nAdjacent bone\n Globe (eyeball)\n Optic nerve\n Orbital soft tissues\n Periosteum\n\n
\nAdjacent structures, NOS\n Brain\n Pterygoid fossa\n Sinus\n Temporal fossa\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nCervical\nMandibular, NOS\n Submandibular (submaxillary)\nParotid, NOS\nInfra-auricular\nPreauricular\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n
\nIn situ: Noninvasive; intraepithelial\n\n
\nAny size tumor confined to orbit\n No invasion of bony walls or globe\n Confined to orbit (including soft tissues)\n Localized, NOS\n\n
\nInvasion of\n Bony walls\n Orbital tissues (excluding orbit primary site)\nDiffuse invasion of orbital tissue and bony walls\n\n
\nInvasion of globe or periorbital structures, including:\n Adjacent paranasal sinuses\n Conjunctiva\n Cranium\n Globe\n\n
\nCentral nervous system\nEyelids\nNasal cavity\nTemporal fossa\nFurther contiguous extension\n\n
\nNo evidence of primary tumor\n\n
\nUnknown; extension not stated\n Primary tumor cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo regional lymph node involvement\n\n
\nCervical, NOS\nMandibular, NOS\n Submandibular (submaxillary)\nParotid, NOS\n Infra-auricular\n Preauricular\n\n
\nRegional lymph node(s), NOS\n Lymph node(s), NOS\n\n
\nUnknown; regional lymph node(s) not stated\n Regional lymph node(s) cannot be assessed\n Not documented in patient record\nDeath Certificate Only\n\n
\nNo distant metastasis\n Unknown if distant metastasis\n\n
\nDistant lymph node(s), NOS\n\n
\nCarcinomatosis\nDistant metastasis WITH or WITHOUT distant lymph node(s)\nDistant metastasis, NOS\n\n
\nDeath Certificate Only\n\n