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Health care providers should administer Tdap during each pregnancy,
first dose as a precaution). The recommended schedule is 0, 4 weeks, and
6 to 12 months. Tdap should replace 1 dose of Td, preferably during the
third trimester (between 27-36 weeks gestation) of pregnancy.
The Advisory Committee on Immunization Practices (ACIP)
states that although no evidence exists that tetanus and diphtheria
toxoids are teratogenic, waiting until the second trimester of pregnancy
to administer a routine Td booster is a reasonable precaution for
minimizing any concern about the theoretical possibility of such
reactions.
preferably during the third trimester (between 27-36 weeks gestation),
although Tdap may be given at any time during pregnancy. If Tdap is not
administered during pregnancy, Tdap should be administered immediately
postpartum.
Pregnant women who have never been vaccinated against tetanus should
receive 3 doses of vaccine containing tetanus and reduced diphtheria
toxoids (again waiting until the second trimester of pregnancy for the
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