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Adults who have never been vaccinated against tetanus, diphtheria, or
tetanus and diphtheria toxin to avoid unnecessary repeat of the
vaccination series. If tetanus and diphtheria antitoxin levels are each
>0.1 IU/mL, previous vaccination with tetanus and diphtheria toxoid
vaccine is presumed, and a single dose of Td or Tdap may be given, as
indicated, for booster immunization.
Adults who received an incomplete vaccination series against tetanus and
diphtheria should be vaccinated with the number of doses of Tdap and/or
Td needed to complete the 3-dose primary series of tetanus and diphtheria
toxoid-containing vaccines. A single dose of Tdap can be used in the
pertussis (no dose of pediatric DTP/DTaP/DT or Td) should receive a
series.
series of three vaccinations containing tetanus and diphtheria toxoids.
The preferred schedule is a single dose of Tdap, followed by a dose of Td
>3 weeks after Tdap and another dose of Td 6-12 months later. However,
Tdap can substitute for any one of the doses of Td in the 3-dose primary
series. Alternatively, in situations in which the adult probably received
vaccination against tetanus and diphtheria but cannot produce a record,
vaccine providers may consider serologic testing for antibodies to
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