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This test is a specific immunological test that measures the level of Immunoglob
ulin E (IgE) antibodies against cobalt in a person's blood serum. IgE antibodies
are produced by the immune system in response to exposure to certain allergens
or substances, and their presence indicates an allergic reaction. This test is
used to help diagnose occupational asthma or other respiratory allergic conditio
ns caused by exposure to cobalt, which is a low molecular weight agent commonly
found in various industrial and manufacturing settings.[PMID 7939614]
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