DBIA2888    ICR (2888)

The diagnosis date refers to the first diagnosis of this
cancer by any recognized medical practitioner.

The Topography section of the International
Classification of Diseases for Oncology (ICD-O, 1990) is used for coding the
Primary Site of all cancers reported to SEER.

Histology is a six-digit code consisting of three parts:

A  Histologic type (4 digits)
B  Behavior (1 digit)
C  Grading or differentiation; or for lymphomas and leukemias
designation of T-cell, B-cell, and null cell (1 digit)

"Grade or Differentiation" of the tumor describes the
tumor's resemblance to normal tissue.  Well differentiated (grade I) is the
most like normal tissue.

SIZE OF TUMOR is the largest dimension, or the diameter
of the primary tumor, and is always recorded in millimeters.

CLINICAL STAGE GROUP defines the anatomic extent of
disease based on the previously coded T, N, and M elements.

CLINICAL T evaluates the primary tumor and reflects tumor
size and/or       extension.

CLINICAL N identifies the absence or presence of regional
lymph node metastases and describes the extent of regional lymph node
metastases.

CLINCIAL M records the presence or absence of distant
metastases.

PATHOLOGIC T evaluates the primary tumor and identifies
tumor size and/or extension.

PATHOLOGIC N identifies the absence or presence of
regional lymph node      metastases and describes the extent of regional lymph
node metastases.

PATHOLOGIC M records the presence or absence of distant
metastases.

PATHOLOGIC STAGE GROUP defines the anatomic extent of
disease based on the T, N, and M elements.

SURGERY OF PRIMARY SITE DATE is the date that
cancer-directed surgery was performed.

RADIATION DATE is the date the first course of radiation
therapy was started.

RADIATION is the type of radiation administered to the
primary site or any metastatic site.

CHEMOTHERAPY DATE is the date the first course of
chemotherapy was started.

CHEMOTHERAPY is the type of chemotherapy administered as
the first course of treatment.

HORMONE THERAPY DATE is the date hormone therapy was
started.

HORMONE THERAPY is the type of hormone therapy the
patient received as part of the first course of treatment.

IMMUNOTHERAPY DATE is the date immunotherapy was started.

IMMUNOTHERAPY (BRM) is the type of immunotherapy the
patient received as part of the first course of treatment.

RADIATION TREATMENT VOLUME is intended primarily to
provide a simple expression of the most common radiation volumes treated.

NON CANCER-DIRECTED SURGERY is a surgical procedure
performed to diagnose/stage disease (exploratory) or for relief of symptoms
(palliative).

INTENT OF RADIATION is the intent of the radiation
treatment.  This item is useful in assessing the appropriateness of the
treatment and correlating the outcome with the original intent of the
treatment.

NON CANCER-DIRECTED SURG DATE is the date that non
cancer-directed surgery was performed.

SURGERY OF PRIMARY SITE modifies, controls, removes, or
destroys proliferating cancer tissue.

RADIATION COMPLETION STATUS indicates whether the
patient's radiation therapy was completed as outlined in the initial treatment
plan.

ABSTRACT STATUS is the status of the abstract data entry.

PROTOCOL ELIGIBILITY STATUS is the eligibility status of
the patient to be entered into a protocol.

PROTOCOL PARTICIPATION records whether the patient was
enrolled in and treated on a protocol.

REGIONAL DOSE:cGy is used to code the dominant or most
clinically significant dose delivered.