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Global: ^PS(51.26

Package: Pharmacy Data Management

Global: ^PS(51.26

Information

FileMan FileNo	FileMan Filename	Package
51.26	PHARMACOGENOMIC GENES	Pharmacy Data Management

Description

Per VHA Directive 2005-044, this file has been "locked down" by Data Standardization (DS). The file definition (i.e. data dictionary) shall not be modified. All additions, changes and deletions to entries in the file shall be done by Enterprise Reference Terminology (ERT) using the Master File Server (MFS), provided by Common Services (CS). Creating and/or editing locally defined fields in the file are not permitted. Use of locally defined fields that were created prior to the VHA Directive's 2005-044 effective date shall not be supported. This file contains a list of standard genes, associated synonyms, and a corresponding vendor gene for every standard gene. The associated vendor gene will be used for the pharmacogenomic order checks provided by the vendor. Updates cannot be made at a local facility.

Pointed To By FileMan Files, Total: 1

Package	Total	FileMan Files
Pharmacy Data Management	1	PHARMACOGENOMIC GENES(#51.26)[99.97]

Pointer To FileMan Files, Total: 2

Package	Total	FileMan Files
Pharmacy Data Management	2	PHARMACOGENOMIC GENES(#51.26)[99.97] PHARMACOGENOMIC PHENOTYPES(#51.28)[#51.263(.01)]

Fields, Total: 8

Field #	Name	Loc	Type	Details
.01	NAME	0;1	FREE TEXT	**********************REQUIRED FIELD********************** INPUT TRANSFORM: `K:$L(X)>25!($L(X)<1)!'(X'?1P.E) X` `MAXIMUM LENGTH: 25` LAST EDITED: `APR 23, 2025` HELP-PROMPT: `Enter the name of the Gene. The answer must be 1-25 characters in length.` DESCRIPTION: `This is the name of the Gene. This field, in addition to the synonyms also in this file, will enable the software to derive a vendor gene to be used in the pharmacogenomic order check for medication orders.` PRE-LOOKUP: `I $G(DIC(0))["L",'$D(XUMF) K X D EN^DDIOL("Entries must be edited via the Master File Server (MFS).","","!?5")` DELETE TEST: `1,0)= D:'$D(XUMF) EN^DDIOL("Entries must be inactivated via the Master File Server(MFS).","","!?5") I '$D(XUMF)` LAYGO TEST: `1,0)= D:'$D(XUMF) EN^DDIOL("Entries must be added via the Master File Server(MFS).","","!?5") I $D(XUMF)` `WRITE AUTHORITY: ^` FIELD INDEX: `B (#1767) REGULAR IR LOOKUP & SORTING` `Short Descr: This cross reference sets the global PS(51.26,"B",X,DA)="".` `Description: This is the "B" cross reference on the NAME (#01) Field. This cross reference, along with the Synonym and Name cross references, will be used when converting a Gene from a lab test to a First DataBank Gene, enabling` `successful pharmacogenomic order checking.` `Set Logic: S ^PS(51.26,"B",$E(X,1,25),DA)=""` `Kill Logic: K ^PS(51.26,"B",$E(X,1,25),DA)` `Whole Kill: K ^PS(51.26,"B")` `X(1): NAME (51.26,.01) (Subscr 1) (Len 25) (forwards)`
1	FIRST DATABANK GENE	0;2	FREE TEXT	INPUT TRANSFORM: `K:$L(X)>25!($L(X)<1) X` `MAXIMUM LENGTH: 25` LAST EDITED: `APR 23, 2025` HELP-PROMPT: `Enter the name of the First Databank Gene. The answer must be 1-25 characters in length.` DESCRIPTION: `This field provides the mapping from the lab test Gene to the First DataBank Gene. The First DataBank Gene will be used when processing the pharmacogenomic order checks provided by First DataBank.` FIELD INDEX: `C (#1768) REGULAR IR LOOKUP & SORTING` `Short Descr: This cross reference sets the global PS(51.26,"C",X,DA)="".` `Description: This is the "C" cross reference on the FIRST DATABANK GENE (#1) Field. This cross reference, along with the Synonym and Name cross references, will be used when converting a Gene from a lab test to a corresponding First` `DataBank Gene, enabling successful pharmacogenomic order checking.` `Set Logic: S ^PS(51.26,"C",$E(X,1,25),DA)=""` `Kill Logic: K ^PS(51.26,"C",$E(X,1,25),DA)` `Whole Kill: K ^PS(51.26,"C")` `X(1): FIRST DATABANK GENE (51.26,1) (Subscr 1) (Len 25) (forwards)`
2	SYNONYM	1;0	Multiple #51.262	51.262 DESCRIPTION: `This multiple contains a list of synonyms for the NAME field, which is the name of the Gene.`
3	STANDARD PHENOTYPE	2;0	POINTER Multiple #51.263	51.263 DESCRIPTION: `This multiple contains a list of Phenotypes that are appropriate for the Gene.`
99.97	REPLACED BY VHA STANDARD TERM	VUID;3	POINTER TO PHARMACOGENOMIC GENES FILE (#51.26)	PHARMACOGENOMIC GENES(#51.26) LAST EDITED: `APR 22, 2025` HELP-PROMPT: `Enter the VHA standard term that replaces this term.` DESCRIPTION: `This field is populated when one Term/Concept replaces another Term/Concept. This field is controlled by standardization and should only be changed by standardization processes. This field contains a pointer to a VHA` `standard term that replaces this entry.` CROSS-REFERENCE: `51.26^AREPLACETERM` `1)= S ^PS(51.26,"AREPLACETERM",$E(X,1,30),DA)=""` `2)= K ^PS(51.26,"AREPLACETERM",$E(X,1,30),DA)` `This cross-reference can be used to identify the replacement entries associated with a Term/Concept.`
99.98	MASTER ENTRY FOR VUID	VUID;2	SET	'0' FOR NO; '1' FOR YES; LAST EDITED: `APR 22, 2025` HELP-PROMPT: `Enter '1' for 'Yes' if this entry is the Master entry for this VUID.` DESCRIPTION: `This field identifies the Master entry for a VUID associated with a Term/Concept.` RECORD INDEXES: `AMASTERVUID (#1766)`
99.99	VUID	VUID;1	FREE TEXT	INPUT TRANSFORM: `K:$L(X)>20!($L(X)<1) X` `MAXIMUM LENGTH: 20` LAST EDITED: `APR 22, 2025` HELP-PROMPT: `Enter the VHA Unique ID (VUID) that represents this VHA wide term.` DESCRIPTION: `This number represents the VHA Unique ID (VUID). It is a unique meaningless integer assigned to reference terms VHA wide.` RECORD INDEXES: `AMASTERVUID (#1766)`
99.991	EFFECTIVE DATE/TIME	TERMSTATUS;0	DATE Multiple #51.2699	51.2699 DESCRIPTION: `This multiple field contains the history of changes to the status of this reference term, along with the date/time of each change.`

Found Entries, Total: 48

NAME: ABCB1	NAME: ABCG2	NAME: ADRA2A	NAME: ANKK1	NAME: APOE	NAME: BCHE	NAME: CACNA1S	NAME: COMT
NAME: CYP1A2	NAME: CYP2B6	NAME: CYP2C	NAME: CYP2C19	NAME: CYP2C8	NAME: CYP2C9	NAME: CYP2D6	NAME: CYP3A4
NAME: CYP3A5	NAME: CYP4F2	NAME: DPYD	NAME: F2	NAME: F5	NAME: G6PD	NAME: GRIK4	NAME: HLA-A 31:01
NAME: HLA-A 33:03	NAME: HLA-B 13:01	NAME: HLA-B 15:02	NAME: HLA-B 15:11	NAME: HLA-B 38:02	NAME: HLA-B 40:01	NAME: HLA-B 57:01	NAME: HLA-B 58:01
NAME: HLA-B 59:01	NAME: HTR2A	NAME: HTR2C	NAME: IFNL4	NAME: MTHFR	NAME: MT-RNR1	NAME: NAT2	NAME: NUDT15
NAME: OPRM1	NAME: RYR1	NAME: SLCO1B1	NAME: TPMT	NAME: UGT1A1	NAME: UGT2B15	NAME: VKORC1	NAME: IFNL3

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